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Cancer Chemotherapy and Pharmacology

Issue 2/2008

Content (25 Articles)

Original Article

Further mechanistic unravelling of the influence of the cell cycle effects on the radiosensitising mechanism of vinflunine, in vitro

Cindy Simoens, Bea Pauwels, Jan B. Vermorken, Greet G. O. Pattyn, Hilde A. J. Lambrechts, Fabienne Breillout, Filip Lardon

Original Article

Tritherapy with fluorouracil/leucovorin, irinotecan and oxaliplatin (FOLFIRINOX): a phase II study in colorectal cancer patients with non-resectable liver metastases

M. Ychou, F. Viret, A. Kramar, F. Desseigne, E. Mitry, R. Guimbaud, J. R. Delpero, M. Rivoire, F. Quénet, G. Portier, B. Nordlinger

Original Article

The relative bioavailability of gefitinib administered by granular formulation

Mireille V. Cantarini, Chris J. Bailey, Barbara Collins, Robert P. Smith

Original Article

Phase II study of rubitecan in recurrent or metastatic head and neck cancer

Francesco Caponigro, Giacomo Cartenì, Jean Pierre Droz, Amalia Milano, Wayne B. Davis, Patricia Pollard

Original Article

Effect of dalteparin and radiation on survival and thromboembolic events in glioblastoma multiforme: a phase II ECOG trial

H. Ian Robins, Anne O’Neill, Mark Gilbert, Mark Olsen, Ronald Sapiente, Brian Berkey, Minesh Mehta

Original Article

Effect of N-acetylcysteine route of administration on chemoprotection against cisplatin-induced toxicity in rat models

D. Thomas Dickey, Leslie L. Muldoon, Nancy D. Doolittle, Darryl R. Peterson, Dale F. Kraemer, Edward A. Neuwelt

Original Article

A phase I study of docetaxel with ketoconazole modulation in patients with advanced cancers

Wei-Peng Yong, Ling-Zhi Wang, Lai-San Tham, Chiung-Ing Wong, Soo-Chin Lee, Ross Soo, Norita Sukri, How-Sung Lee, Boon-Cher Goh

Original Article

Randomized phase II study of cisplatin and 5-FU continuous infusion (PF) versus cisplatin, UFT and vinorelbine (UFTVP) as induction chemotherapy in locally advanced squamous cell head and neck cancer (LA-SCHNC)

Fernando Rivera, M. Eugenia Vega-Villegas, Marta López-Brea, Dolores Isla, Marta Mayorga, Piedad Galdós, Antonio Rubio, Adolfo Del Valle, Fe García-Reija, Belen García-Montesinos, Julio Rodríguez-Iglesias, Jose Mayordomo, Julio Rama, Ramón Saiz-Bustillo, Jaime Sanz-Ortiz

Original Article

Pemetrexed and cisplatin in patients with advanced gastric cancer: a Korean cancer study group multicenter phase II study

Yeul Hong Kim, Hyun Cheol Chung, Won Ki Kang, Sook Ryun Park, Chul Soo Kim, Tae-Yue Kim, Sang Won Shin, Byung-Joo Park, Soo Jin Cha, Yung-Jue Bang

Original Article

Changes of cytokines in cirrhosis patients with advanced hepatocellular carcinoma treated by intra-arterial chemotherapy

Hidenari Nagai, Daisuke Miyaki, Teppei Matsui, Masahiro Kanayama, Katsuya Higami, Kouichi Momiyama, Takashi Ikehara, Manabu Watanabe, Yasukiyo Sumino, Kazumasa Miki

Original Article

Multicenter phase-II trial of irinotecan plus oxaliplatin [IROX regimen] in patients with poor-prognosis cancer of unknown primary: a hellenic cooperative oncology group study

E. Briasoulis, G. Fountzilas, A. Bamias, M. A. Dimopoulos, N. Xiros, G. Aravantinos, E. Samantas, H. Kalofonos, T. Makatsoris, N. Mylonakis, P. Papakostas, D. Skarlos, I. Varthalitis, N. Pavlidis

Original Article

Liposomal pegylated doxorubicin plus vinorelbine combination as first-line chemotherapy for metastatic breast cancer in elderly women ≥65 years of age

Raffaele Addeo, Vincenzo Faiola, Rosario Guarrasi, Liliana Montella, Bruno Vincenzi, Elena Capasso, Gregorio Cennamo, Maria Saveria Rotundo, Pierosandro Tagliaferri, Michele Caraglia, Salvatore Del Prete

Original Article

Temozolomide in combination with fotemustine in patients with metastatic melanoma

Faruk Tas, Hakan Camlica, Erkan Topuz

Original Article

Irinotecan plus cisplatin and dexamethasone (ICD) combination chemotherapy for patients with diffuse large B-cell lymphoma previously treated with Rituximab plus CHOP

Hye Jin Kang, Won Seog Kim, Cheolwon Suh, Yeon Hee Park, Bong Seog Kim, Young Jin Yuh, Baek-Yeol Ryoo

Original Article

Antiproliferative effects of rapamycin as a single agent and in combination with carboplatin and paclitaxel in head and neck cancer cell lines

Nasredine Aissat, Christophe Le Tourneau, Aïda Ghoul, Maria Serova, Ivan Bieche, François Lokiec, Eric Raymond, Sandrine Faivre

Original Article

Extracellular signal-regulated kinase phosphorylation due to menadione-induced arylation mediates growth inhibition of pancreas cancer cells

Shinji Osada, Fumio Sakashita, Yosiki Hosono, Kenichi Nonaka, Yasuharu Tokuyama, Hidenori Tanaka, Yoshiyuki Sasaki, Hiroyuki Tomita, Shuji Komori, Satoshi Matsui, Takao Takahashi

Open Access Original Article

Erufosine, a novel alkylphosphocholine, in acute myeloid leukemia: single activity and combination with other antileukemic drugs

Michael Fiegl, Lars H. Lindner, Matthias Juergens, Hansjoerg Eibl, Wolfgang Hiddemann, Jan Braess

Original Article

Syndrome of inappropriate secretion of antidiuretic hormone after chemotherapy with vinorelbine

Hiroaki Kuroda, Masafumi Kawamura, Tai Hato, Kazunori Kamiya, Masahiro Kawakubo, Yotaro Izumi, Masazumi Watanabe, Hirohisa Horinouchi, Koichi Kobayashi

Erratum

Syndrome of inappropriate secretion of antidiuretic hormone after chemotherapy with vinorelbine

Hiroaki Kuroda, Masafumi Kawamura, Tai Hato, Kazunori Kamiya, Masahiro Kawakubo, Yotaro Izumi, Masazumi Watanabe, Hirohisa Horinouchi, Koichi Kobayashi, Mitsuo Nakayama

Clinical Trial Report

Phase I trial of PEG-interferon and recombinant IL-2 in patients with metastatic renal cell carcinoma

Saby George, Thomas E. Hutson, Tarek Mekhail, Laura Wood, James Finke, Paul Elson, Robert Dreicer, Ronald M. Bukowski

Clinical Trial Report

Phase I clinical trial of intrathecal gemcitabine in patients with neoplastic meningitis

Ronald J. Bernardi, Lisa Bomgaars, Elizabeth Fox, Frank M. Balis, Merrill J. Egorin, Theodore F. Lagattuta, Alberta Aikin, Patricia Whitcomb, Jamie Renbarger, Frank S. Lieberman, Stacey L. Berg, Susan M. Blaney

Short Communication

Concentrations of the DNA methyltransferase inhibitor 5-fluoro-2′-deoxycytidine (FdCyd) and its cytotoxic metabolites in plasma of patients treated with FdCyd and tetrahydrouridine (THU)

Jan H. Beumer, Robert A. Parise, Edward M. Newman, James H. Doroshow, Timothy W. Synold, Heinz-Josef Lenz, Merrill J. Egorin

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Keynote webinar | Spotlight on antibody–drug conjugates in cancer

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