Issue 1/2018
Content (24 Articles)
The promise and challenges of exploiting the proton-coupled folate transporter for selective therapeutic targeting of cancer
Larry H. Matherly, Zhanjun Hou, Aleem Gangjee
Advances in ovarian cancer therapy
Alexander J. Cortez, Patrycja Tudrej, Katarzyna A. Kujawa, Katarzyna M. Lisowska
Determination of the absolute oral bioavailability of niraparib by simultaneous administration of a 14C-microtracer and therapeutic dose in cancer patients
L. van Andel, H. Rosing, Z. Zhang, L. Hughes, V. Kansra, M. Sanghvi, M. M. Tibben, A. Gebretensae, J. H. M. Schellens, J. H. Beijnen
Correction to: Determination of the absolute oral bioavailability of niraparib by simultaneous administration of a 14C-microtracer and therapeutic dose in cancer patients
L. van Andel, H. Rosing, Z. Zhang, L. Hughes, V. Kansra, M. Sanghvi, M. M. Tibben, A. Gebretensae, J. H. M. Schellens, J. H. Beijnen
Therapeutic potential of the metabolic modulator Metformin on osteosarcoma cancer stem-like cells
Daniela I. Paiva-Oliveira, Sara R. Martins-Neves, Antero J. Abrunhosa, Carlos Fontes-Ribeiro, Célia M. F. Gomes
Randomized phase III trial comparing surgery alone to UFT + PSK for stage II rectal cancer (JFMC38 trial)
Kiyotaka Okuno, Toru Aoyama, Koji Oba, Noboru Yokoyama, Nobuhisa Matsuhashi, Katsuyuki Kunieda, Yoji Nishimura, Hiroki Akamatsu, Takaya Kobatake, Satoshi Morita, Takaki Yoshikawa, Junichi Sakamoto, Shigetoyo Saji
A drug–drug interaction study to assess the effect of the CYP1A2 inhibitor fluvoxamine on the pharmacokinetics of dovitinib (TKI258) in patients with advanced solid tumors
Vincent A. de Weger, Sanjay Goel, Roger von Moos, Jan H. M. Schellens, Nicholas Mach, Eugene Tan, Suraj Anand, Jeffrey W. Scott, Ulrik Lassen
Phase II study of nedaplatin and irinotecan as adjuvant chemotherapy for completely resected non-small cell lung cancer
Shuji Murakami, Haruhiro Saito, Tetsuro Kondo, Hiroyuki Ito, Fumihiro Oshita, Kouzo Yamada
Population pharmacokinetics of nintedanib, an inhibitor of tyrosine kinases, in patients with non-small cell lung cancer or idiopathic pulmonary fibrosis
Ulrike Schmid, Karl-Heinz Liesenfeld, Angele Fleury, Claudia Dallinger, Matthias Freiwald
A phase II study of biweekly gemcitabine and carboplatin in completely resected stage IB-IIIA non-small cell lung cancer
Reiko Sakurai, Yoshio Tomizawa, Akihiro Yoshii, Yosuke Miura, Hiroaki Tsurumaki, Kyoichi Kaira, Noriaki Sunaga, Osamu Kawashima, Takeshi Hisada, Masanobu Yamada, Ryusei Saito
Efficacy of combination chemotherapy using irinotecan and nedaplatin for patients with recurrent and refractory endometrial carcinomas: preliminary analysis and literature review
Morikazu Miyamoto, Masashi Takano, Mika Kuwahara, Hiroaki Soyama, Kento Kato, Hiroko Matuura, Takahiro Sakamoto, Kazuki Takasaki, Tadashi Aoyama, Tomoyuki Yoshikawa, Kenichi Furuya
DPYD*2A and MTHFR C677T predict toxicity and efficacy, respectively, in patients on chemotherapy with 5-fluorouracil for colorectal cancer
Noor Ahmed Nahid, Mohd Nazmul Hasan Apu, Md. Reazul Islam, Samia Shabnaz, Surid Mohammad Chowdhury, Maizbha Uddin Ahmed, Zabun Nahar, Md. Siddiqul Islam, Mohammad Safiqul Islam, Abul Hasnat
The extent of ground-glass attenuation is a risk factor of chemotherapy-related exacerbation of interstitial lung disease in patients with non-small cell lung cancer
Takeshi Masuda, Chihiro Hirano, Yasushi Horimasu, Taku Nakashima, Shintarou Miyamoto, Hiroshi Iwamoto, Shinichiro Ohshimo, Kazunori Fujitaka, Hironobu Hamada, Noboru Hattori
Relationship between LAT1 expression and resistance to chemotherapy in pancreatic ductal adenocarcinoma
Bolag Altan, Kyoichi Kaira, Akira Watanabe, Norio Kubo, Pinjie Bao, Gantumur Dolgormaa, Erkhem-Ochir Bilguun, Kenichiro Araki, Yoshikatsu Kanai, Takehiko Yokobori, Tetsunari Oyama, Masahiko Nishiyama, Hiroyuki Kuwano, Ken Shirabe
Pharmacokinetic and toxicodynamic evaluation of oxaliplatin-induced neuropathy and hematological toxicity in rats
Yukako Ito, Shinji Kobuchi, Risa Shimizu, Yosuke Katsuyama
Dose and schedule modification are required for long-term continuation of sunitinib in Japanese patients with advanced pancreatic neuroendocrine tumors
Lingaku Lee, Tetsuhide Ito, Hisato Igarashi, Masami Miki, Nao Fujimori, Ken Kawabe, Robert T. Jensen, Yoshihiro Ogawa
Persistent cytarabine and daunorubicin exposure after administration of novel liposomal formulation CPX-351: population pharmacokinetic assessment
Mina Nikanjam, Edmund V. Capparelli, Jeffrey E. Lancet, Arthur Louie, Gary Schiller
Pharmacokinetics and safety of panitumumab in a patient with chronic kidney disease
L. L. Krens, J. M. Baas, H. J. Guchelaar, H. Gelderblom
Pharmacogenetic study of the impact of ABCB1 single-nucleotide polymorphisms on lenalidomide treatment outcomes in patients with multiple myeloma: results from a phase IV observational study and subsequent phase II clinical trial
Ingrid Jakobsen Falk, Johan Lund, Henrik Gréen, Astrid Gruber, Evren Alici, Birgitta Lauri, Cecilie Blimark, Ulf-Henrik Mellqvist, Agneta Swedin, Karin Forsberg, Conny Carlsson, Mats Hardling, Lucia Ahlberg, Kourosh Lotfi, Hareth Nahi
Mass balance, metabolic disposition, and pharmacokinetics of a single oral dose of regorafenib in healthy human subjects
Michael Gerisch, Frank-Thorsten Hafner, Dieter Lang, Martin Radtke, Konstanze Diefenbach, Adriaan Cleton, John Lettieri
The earlier, the better: the effects of different administration timepoints of sorafenib in suppressing the carcinogenesis of VEGF in rats
Nan Li, Bin Chen, Run Lin, Ni Liu, Hai-tao Dai, Ke-yu Tang, Jian-yong Yang, Yong-hui Huang
Asparaginase Erwinia chrysanthemi effectively depletes plasma glutamine in adult patients with relapsed/refractory acute myeloid leukemia
Ashkan Emadi, Jennie Y. Law, Erin T. Strovel, Rena G. Lapidus, Linda J. B. Jeng, Myounghee Lee, Miriam G. Blitzer, Brandon A. Carter-Cooper, Danielle Sewell, Isabella Van Der Merwe, Sunita Philip, Mohammad Imran, Stephen L. Yu, Hongxia Li, Philip C. Amrein, Vu H. Duong, Edward A. Sausville, Maria R. Baer, Amir T. Fathi, Zeba Singh, Søren M. Bentzen
Correction to: Phase II study of bi-weekly temozolomide plus bevacizumab for adult patients with recurrent glioblastoma
Michael A. Badruddoja, Marjorie Pazzi, Abhay Sanan, Kurt Schroeder, Kevin Kuzma, Thomas Norton, Thomas Scully, Daruka Mahadevan, Michael Malek Ahmadi
Correction to: Innovative intraoral cooling device better tolerated and equally effective as ice cooling
Java Walladbegi, Martin Gellerstedt, Anncarin Svanberg, Mats Jontell