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Cancer Chemotherapy and Pharmacology

Issue 1/2007

Content (18 Articles)

Original Article

Phase II trial of a 2-h infusion of gemcitabine plus carboplatin as first-line chemotherapy for advanced non-small-cell lung cancer

N. Xu, P. Shen, X. C. Zhang, L. F. Yu, H. Y. Bao, G. M. Shi, S. Huang, J. Chen, H. B. Mou, W. J. Fang

Original Article

A combination therapy with transarterial chemo-lipiodolization and systemic chemo-infusion for large extensive hepatocellular carcinoma invading portal vein in comparison with conservative management

Jeong Won Jang, Si Hyun Bae, Jong Young Choi, Hyun Jong Oh, Min Soo Kim, So Yeon Lee, Chang Wook Kim, U Im Chang, Soon Woo Nam, Sang Bok Cha, Young Joon Lee, Ho Jong Chun, Byung Gil Choi, Jae Young Byun, Seung Kew Yoon

Original Article

Phase II study of docetaxel and cisplatin combination chemotherapy in metastatic gastric cancer

Keon Woo Park, Jin Seok Ahn, Young Suk Park, Jeeyun Lee, Jung Hoon Kang, Joon Oh Park, Ho Yeong Lim, Young-Hyuck Im, Won Ki Kang, Keunchil Park, Soon Il Lee

Original Article

Thalidomide and celecoxib as potential modulators of irinotecan’s activity in cancer patients

Miguel Villalona-Calero, Larry Schaaf, Gary Phillips, Gregory Otterson, Kevin Panico, Wenrui Duan, Barbara Kleiber, Manisha Shah, Donn Young, Wan-Hong Wu, John Kuhn

Original Article

Early intervention with epoetin beta prevents severe anaemia in patients with solid tumours receiving platinum-based chemotherapy: results of the NeoPrevent study

Javier de Castro, Amalio Ordóñez, Dolores Isla, Alfredo Sánchez, Antonio Arrivi, José Luis Manzano, Manuel González Barón

Original Article

A pharmacokinetic and safety study of a novel polymeric paclitaxel formulation for oral application

S. A. Veltkamp, C. Alderden-Los, A. Sharma, H. Rosing, J. H. Beijnen, J. H. M. Schellens

Original Article

A phase I–II study of bi-weekly gemcitabine and irinotecan as second-line chemotherapy in non-small cell lung cancer after prior taxane + platinum-based regimens

Christos Kosmas, Nicolas Tsavaris, Konstantinos Syrigos, Angelos Koutras, George Tsakonas, Thomas Makatsoris, Nicolas Mylonakis, Athanasios Karabelis, George P. Stathopoulos, Haralambos P. Kalofonos

Original Article

Novel tetrahydroisoquinolin-ethyl-phenylamine based multidrug resistance inhibitors with broad-spectrum modulating properties

Veronika Jekerle, Werner Klinkhammer, Raymond M. Reilly, Micheline Piquette-Miller, Michael Wiese

Original Article

Amifostine and glutathione prevent ifosfamide- and acrolein-induced hemorrhagic cystitis

C. K. L. P. Batista, J. M. S. C. Mota, M. L. P. Souza, B. T. A. Leitão, M. H. L. P. Souza, G. A. C. Brito, F. Q. Cunha, R. A. Ribeiro

Original Article

A phase I clinical and pharmacokinetic study of the multi-drug resistance protein-1 (MRP-1) inhibitor sulindac, in combination with epirubicin in patients with advanced cancer

R. O’Connor, M. O’Leary, J. Ballot, C. D. Collins, P. Kinsella, D. E. Mager, R. D. Arnold, L. O’Driscoll, A. Larkin, S. Kennedy, D. Fennelly, M. Clynes, J. Crown

Original Article

Fatality involving vinblastine overdose as a result of a complex medical error

Małgorzata Kłys, Tomasz Konopka, Mariusz Ścisłowski, Piotr Kowalski

Original Article

Monocyte fructose 1,6-bisphosphatase and cytidine deaminase enzyme activities: potential pharmacodynamic measures of calcitriol effects in cancer patients

Josephia R. Muindi, Yibing Peng, John W. Wilson, Candace S. Johnson, Robert A. Branch, Donald L. Trump

Original Article

Pharmacokinetics and tumor uptake of a derivatized form of paclitaxel associated to a cholesterol-rich nanoemulsion (LDE) in patients with gynecologic cancers

Maria L. N. Dias, Jesus P. Carvalho, Debora G. Rodrigues, Silvia R. Graziani, Raul C. Maranhão

Original Article

Combination therapy of human pancreatic cancer implanted in nude mice by oral fluoropyrimidine anticancer agent (S-1) with interferon-alpha

Kotaro Miyake, Kunihiro Tsuchida, Hiromu Sugino, Satoru Imura, Yuji Morine, Masahiko Fujii, Mitsuo Shimada

Clinical Trial Report

A phase I study of the safety and pharmacokinetics of edotecarin (J-107088), a novel topoisomerase I inhibitor, in patients with advanced solid tumors

Herbert I. Hurwitz, Roger B. Cohen, J. Patrick McGovren, Samit Hirawat, William P. Petros, Yutaka Natsumeda, Tomoko Yoshinari

Webinar | 19-02-2024 | 17:30 (CET)

Keynote webinar | Spotlight on antibody–drug conjugates in cancer

Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.

Dr. Véronique Diéras
Prof. Fabrice Barlesi
Developed by: Springer Medicine