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Annals of Hematology
Published in: Annals of Hematology 5/2015

01-05-2015 | Letter to the Editor

Calreticulin mutations are not present in patients with myeloproliferative chronic myelomonocytic leukemia

Authors: Lurdes Zamora, Ulrich Germing, Marta Cabezón, Esther Schuler, Montserrat Arnan, Silvia Marcé, Rosa Coll, Helena Pomares, Carolin Brings, Laura Palomo, Jennifer Schmeneau, David Gallardo, Fuensanta Millá, Evarist Feliu, Blanca Xicoy

Published in: Annals of Hematology | Issue 5/2015

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Excerpt

Dear Editor, …
Literature
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Vardiman JW, Bennett JM, Bain BJ, Baumann I, Thiele J, Orazi A (2008) Myelodysplastic/myeloproliferative neoplasm, unclassifiable. In: Swerdlow SH, Campo E, Harris NL, Jaffe ES, Pileri SA, Stein H, et al.(Edt) WHO classification of tumors of haematopoietic and lymphoid tissues. Lyon, France, pp 76–79
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Itzykson R, Kosmider O, Renneville A, Gelsi-Boyer V, Meggendorfer M, Morabito M, Berthon C, Adès L, Fenaux P, Beyne-Rauzy O, Vey N, Braun T, Haferlach T, Dreyfus F, Cross NC, Preudhomme C, Bernard OA, Fontenay M, Vainchenker W, Schnittger S, Birnbaum D, Droin N, Solary E (2013) Prognostic score including gene mutations in chronic myelomonocytic leukemia. J Clin Oncol 31:2428–2436CrossRefPubMed
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Klampfl T, Gisslinger H, Harutyunyan AS, Nivarthi H, Rumi E, Milosevic JD, Them NC, Berg T, Gisslinger B, Pietra D, Chen D, Vladimer GI, Bagienski K, Milanesi C, Casetti IC, Sant’Antonio E, Ferretti V, Elena C, Schischlik F, Cleary C, Six M, Schalling M, Schönegger A, Bock C, Malcovati L, Pascutto C, Superti-Furga G, Cazzola M, Kralovics R (2013) Somatic mutations of calreticulin in myeloproliferative neoplasms. N Engl J Med 369:2379–2390CrossRefPubMed
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Nangalia J, Massie CE, Baxter EJ, Nice FL, Gundem G, Wedge DC, Avezov E, Li J, Kollmann K, Kent DG, Aziz A, Godfrey AL, Hinton J, Martincorena I, Van Loo P, Jones AV, Guglielmelli P, Tarpey P, Harding HP, Fitzpatrick JD, Goudie CT, Ortmann CA, Loughran SJ, Raine K, Jones DR, Butler AP, Teague JW, O’Meara S, McLaren S, Bianchi M, Silber Y, Dimitropoulou D, Bloxham D, Mudie L, Maddison M, Robinson B, Keohane C, Maclean C, Hill K, Orchard K, Tauro S, Du MQ, Greaves M, Bowen D, Huntly BJ, Harrison CN, Cross NC, Ron D, Vannucchi AM, Papaemmanuil E, Campbell PJ, Green AR (2013) Somatic CALR mutations in myeloproliferative neoplasms with nonmutated JAK2. N Engl J Med 369:2391–2405CrossRefPubMedCentralPubMed
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Rumi E, Pietra D, Ferretti V, Klampfl T, Harutyunyan AS, Milosevic JD, Them NC, Berg T, Elena C, Casetti IC, Milanesi C, Sant’antonio E, Bellini M, Fugazza E, Renna MC, Boveri E, Astori C, Pascutto C, Kralovics R, Cazzola M, Associazione Italiana per la Ricerca sul Cancro Gruppo Italiano Malattie Mieloproliferative Investigators (2014) JAK2 or CALR mutation status defines subtypes of essential thrombocythemia with substantially different clinical course and outcomes. Blood 123:1544–1551CrossRefPubMedCentralPubMed
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Tefferi A, Lasho TL, Finke CM, Knudson RA, Ketterling R, Hanson CH, Maffioli M, Caramazza D, Passamonti F, Pardanani A (2014) CALR vs JAK2 vs MPL-mutated or triple-negative myelofibrosis: clinical, cytogenetic and molecular comparisons. Leukemia 28:1472–1477CrossRefPubMed
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Panagiota V, Thol F, Markus B, Fehse B, Alchalby H, Badbaran A, Lehmann U, Koenecke C, Shahswar R, Chaturvedi A, Stadler M, Eder M, Göhring G, Koenigsmann M, Kloos A, Trummer A, Schroeder T, Kobbe G, Thiede C, Platzbecker U, Schlegelberger B, Kreipe HH, Ganser A, Kröger N, Heuser M (2014) Prognostic effect of calreticulin mutations in patients with myelofibrosis after allogeneic hematopoietic stem cell transplantation. Leukemia 28:1552–1555CrossRefPubMed
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Hou HA, Kuo YY, Chou WC, Chen PH, Tien HF (2014) Calreticulin mutation was rarely detected in patients with myelodysplastic syndrome. Leukemia 28:1555–1557CrossRefPubMed
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Wang SA, Hasserjian RP, Fox PS, Rogers HJ, Geyer JT, Chabot-Richards D, Weinzierl E, Hatem J, Jaso J, Kanagal-Shamanna R, Stingo FC, Patel KP, Mehrotra M, Bueso-Ramos C, Young KH, Dinardo CD, Verstovsek S, Tiu RV, Bagg A, Hsi ED, Arber DA, Foucar K, Luthra R, Orazi A (2014) Atypical chronic myeloid leukemia is clinically distinct from unclassifiable myelodysplastic/myeloproliferative neoplasms. Blood 123:2645–2651CrossRefPubMed
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Heuser M, Panagiota V, Koenecke C, Fehse B, Alchalby H, Badbaran A, Shahswar R, Stadler M, Eder M, Göhring G, Trummer A, Schroeder T, Kobbe G, Thiede C, Platzbecker U, Schlegelberger B, Kroeger N, Ganser A, Thol F (2014) Low frequency of calreticulin mutations in MDS patients. Leukemia 28:1933–1934CrossRefPubMed
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Metadata
Title
Calreticulin mutations are not present in patients with myeloproliferative chronic myelomonocytic leukemia
Authors
Lurdes Zamora
Ulrich Germing
Marta Cabezón
Esther Schuler
Montserrat Arnan
Silvia Marcé
Rosa Coll
Helena Pomares
Carolin Brings
Laura Palomo
Jennifer Schmeneau
David Gallardo
Fuensanta Millá
Evarist Feliu
Blanca Xicoy
Publication date
01-05-2015
Publisher
Springer Berlin Heidelberg
Published in
Annals of Hematology / Issue 5/2015
Print ISSN: 0939-5555
Electronic ISSN: 1432-0584
DOI
https://doi.org/10.1007/s00277-014-2262-2

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