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Bulletin of Experimental Biology and Medicine

Issue 4/2023

Content (32 Articles)

PHYSIOLOGY

Association of Serotonin Receptor Gene Polymorphisms with Regulatory and Adaptive Capacities of Medical Students

Yu. V. Kashina, I. L. Cherednik, V. M. Pokrovsky, S. V. Polishchuk

GENERAL PATHOLOGY AND PATHOLOGICAL PHYSIOLOGY

Molecular Hydrogen Reduces the Degree of Endothelial Alteration under Conditions of Chronic Heart Failure

A. V. Deryugina, D. A. Danilova

Changes in Microcirculation in the Brain, Heart, and Liver in Female Rats with Translational Model of Alcoholic Cardiomyopathy

I. B. Tsorin, A. O. Efimova, M. V. Vititnova, E. O. Ionova, V. V. Barchukov, S. A. Simonenko, S. A. Kryzhanovskii

BIOPHYSICS AND BIOCHEMISTRY

The Role of NMDA Receptor Subunits in the Effect of Memantine on the Brain of Healthy Animals

V. I. Arkhipov, I. Yu. Chernomorets, N. S. Zhuikova, D. A. Fedorov, E. V. Pershina

PHARMACOLOGY AND TOXICOLOGY

Pharmacological Effects of a New Indolinone Derivative in Experimental Pneumonitis in Rats

V. V. Bykov, V. S. Motov, A. V. Bykova, V. A. Khazanov, A. I. Vengerovskii, V. V. Udut

Effect of Paclitaxel on the Hemostatic Potential of the Blood in the Experiment

M. V. Filonova, E. P. Fedorova, A. A. Churin, L. Yu. Kotlovskaya, M. Yu. Kotlovskii, P. O. Fedorova, V. V. Udut

The Effect of Polyene Antibiotic Amphotericin B on Erythrocyte Cytoarchitectonics and Osmotic Resistance

L. O. Sokolova, E. A. Kalaeva, V. G. Artyukhov, O. V. Putintseva, M. A. Nakvasina, N. V. Litvinov, L. R. Gizetdinova

IMMUNOLOGY AND MICROBIOLOGY

The Influence of the Synthetic Organoselenium Preparation 974zh on the Immunogenic Activity of Yersinia pestis EV Vaccine Strain NIIEG

V. I. Dubrovina, O. V. Yur’eva, T. P. Starovoitova, A. B. Pyatidesyatnikova, T. A. Ivanova, A. V. Grigor’evykh, R. I. Pescherova, S. V. Balakhonov

The Formation of Non-Specific Immunological Memory Phenotype in Human Monocyte-Like THP-1 and U-937 Cell Lines

A. P. Lykov, S. N. Belogorodtsev, E. K. Nemkova, A. Vetlugina, T. M. Terekhova, Y. Sh. Schwartz

ONCOLOGY

Dynamics of Soluble Forms of the Immune Checkpoint Components PD-1/PD-L1/B7-H3, CD314/ULBP1, and HLA-G in Peripheral Blood of Melanoma Patients Receiving Blockers of Programmed Cell Death Protein PD-1

E. S. Gershtein, A. S. Mochalova, E. A. Korotkova, E. V. Samoilova, O. I. Vashketova, Yu.B. Kuz’min, N. Yu. Sokolov, N. E. Kushlinskii

EXPERIMENTAL METHODS FOR CLINICAL PRACTICE

Effective Connectivity of the Bilateral Amygdala, Dorsomedial Prefrontal, and Subgenual Anterior Cingulate Cortices: Feasibility of Positive Social Emotion Regulation Models for Real-Time Functional Magnetic Resonance Imaging

D. D. Bezmaternykh, M. E. Mel’nikov, E. D. Petrovskii, K. G. Mazhirina, A. A. Savelov, K. V. Kalgin, M. B. Shtark, Y. A. Koush

PRIMATOLOGY

Individual Features of the Hypothalamic—Pituitary—Thyroid Axis Functioning during Aging in Non-Human Primates

N. D. Goncharova, A. M. Ermolaeva, O. A. Chigarova, T. E. Oganyan, L. G. Ivanova, N. V. Timoshenko

EXPERIMENTAL BIOLOGY

Assessment of Ante- and Postnatal Development of the Offspring of Male Rats Crossed in Delayed Periods after Treatment with Methotrexate in Low Doses

T. G. Borovskaya, E. A. Bokhan, A. V. Vychuzhanina, Yu.A. Shchemerova, V. E. Goldberg

MORPHOLOGY AND PATHOMORPHOLOGY

Automated Assessment of the Area of Infiltration by CD8+ Cells in Gastric Carcinoma and Areas of Normal Mucosa as a Significant Prognostic Factor

N. V. Danilova, I. A. Mikhailov, V. M. Khomyakov, A. V. Chaika, T. V. Polushkina, T. N. Sotnikova, N. A. Oleinikova, P. G. Mal’kov

METHODS

Preparation of a Single-Cell Suspension from Tumor Biopsy Samples for Single-Cell RNA Sequencing

A. A. Frolova, T. S. Gerashchenko, M. R. Patysheva, A. A. Fedorov, M. M. Tsyganov, U. A. Bokova, O. D. Bragina, M. A. Vostrikova, E. Yu. Garbukov, N. V. Cherdyntseva

CELL TECHNOLOGIES IN BIOLOGY AND MEDICINE

Modeling of Alzheimer’s Disease to Study the Efficacy of Cell Therapy (Review)

A. D. Voronova, E. K. Karsuntseva, O. V. Stepanova, A. V. Chadin, V. V. Shishkina, S. S. Andretsova, G. A. Fursa, S. V. Shport, I. V. Reshetov, V. P. Chekhonin

Alpha-Fetoprotein as a Factor of Differentiation and Functional Activity of Myeloid-Derived Suppressor Cells

K. Yu. Shardina, S. A. Zamorina, V. P. Timganova, M. S. Bochkova, S. V. Uzhviyuk, V. A. Chereshnev

Regulation of Morphogenetic Processes during Postnatal Development and Physiological Regeneration of the Adrenal Medulla

S. S. Obernikhin, N. V. Yaglova, E. P. Timokhina, S. V. Nazimova, V. V. Yaglov

Gene Expression Profile of 3D Spheroids in Comparison with 2D Cell Cultures and Tissue Strains of Diffuse High-Grade Gliomas

I. V. Arutyunyan, A. G. Soboleva, E. A. Kovtunov, A. M. Kosyreva, V. V. Kudelkina, A. I. Alekseeva, A. V. Elchaninov, E. D. Jumaniyazova, D. V. Goldshtein, G. B. Bolshakova, T. Kh. Fatkhudinov

Development of a Method for Isolation of Mature Cardiomyocytes from Human Heart Biopsy Specimens

S. G. Kovalenko, Sh. R. Frolova, V. K. Kramkova, A. K. Berezovskii, M. A. Popov, D. V. Shumakov, D. I. Zybin, E. G. Agafonov, V. V. Dontsov, K. I. Agladze

Endogenous Regeneration of Alveolar Bone by Decellularized Tooth Matrix

A. V. Latyshev, T. I. Danilova, A. V. Kuznetsova, O. P. Popova, N. N. Butorina, A. Yu. Drobyshev, A. A. Ivanov

Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.