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Bulletin of Experimental Biology and Medicine

Issue 4/2019

This issue is a translation of Byulleten' Eksperimental'noi Biologii i Meditsiny (Bulletin of Experimental Biology and Medicine) and Kletochnye Tekhnologii v Biologii i Meditsine (Cell Technologies in Biology and Medicine)

Content (35 Articles)

GENERAL PATHOLOGY AND PATHOPHYSIOLOGY

Peculiarities of Immediate Response of Respiratory Chain Enzymes in Rat Cerebral Cortex to Hypoxia

L. D. Luk’yanova, Yu. I. Kirova, E. L. Germanova

Blood Cytokine Profile in Rats with Different Behavioral Characteristics after Metabolic Stress

N. V. Kirbaeva, V. S. Evstratova, N. A. Riger, A. Yu. Abramova, S. S. Pertsov, A. V. Vasil’ev

Effect of Antiobiotic-Induced Disbiosis and Its Correction with Probiotics on Myocardial Tolerance to Ischemia-Reperfusion Injury in SPF Rats

Yu. Yu. Borshchev, A. V. Sinitsa, M. M. Zakharchenko, V. Yu. Borshchev, I. Yu. Burovenko, M. M. Galagudza

Effects of Natural Cytokine Complex on the Myocardial Blood Flow in Normal and under Conditions of Increased Hemodynamic Load

M. S. Tverskaya, L. V. Gankovskaya, V. V. Sukhoparova, A. O. Virganskii, R. V. Gorenkov

PHARMACOLOGY AND TOXICOLOGY

Strategy of Pharmacological Regulation of Intracellular Signal Transduction in Regeneration-Competent Cells

G. N. Zyuz’kov, V. V. Zhdanov, E. V. Udut, L. A. Miroshnichenko, T. Yu. Polyakova, L. A. Stavrova, V. V. Udut

Comparative Analysis of Bioactivity of the Russian-Made Antitumor Substances of the Nitrosourea Group

N. D. Bunyatyan, N. A. Oborotova, L. L. Nikolaeva, N. S. Saprykina, L. M. Borisova, M. P. Kiseleva, A. B. Prokof’ev

Analgesic Activity of Hexaazaisowurtzitane Derivatives

S. G. Krylova, T. N. Povet’eva, E. P. Zueva, N. I. Suslov, E. N. Amosova, T. G. Razina, K. A. Lopatina, O. Yu. Rybalkina, Yu. V. Nesterova, O. G. Afanas’eva, E. A. Kiseleva, S. V. Sysolyatin, D. A. Kulagina, V. V. Zhdanov

Drug with Neuroprotective Properties Noopept Does Not Stimulate Cell Proliferation

L. F. Zainullina, T. V. Ivanova, R. U. Ostrovskaya, T. A. Gudasheva, Yu. V. Vakhitova, S. B. Seredenin

Modulation of Structural and Functional Properties of Human Lymphocytes by Reactive Oxygen Species

M. A. Nakvasina, L. I. Popova, O. V. Lidokhova, V. G. Artyukhov

GENETICS

Association of Regulatory and Adaptive Status in Humans with Serotonergic Transmitter System Gene Polymorphism

V. M. Pokrovskii, Yu. V. Kashina, O. V. Kiek, O. V. Gumerova, V. Yu. Gorbunova, V. G. Abushkevich, A. G. Penzhoyan, N. V. Zabolotskikh

ONCOLOGY

Analysis of Anti-Glycan IgG and IgM Antibodies in Colorectal Cancer

A. A. Tikhonov, E. N. Savvateeva, M. A. Chernichenko, V. V. Maslennikov, D. V. Sidorov, A. Yu. Rubina, N. E. Kushlinskii

EXPERIMENTAL METHODS FOR CLINICAL PRACTICE

Prognostic Risk Models for the Development of Cardiovascular Dysfunction in Adolescents with Essential Hypertension

A. S. Kosovtseva, Т. А. Bairova, L. V. Rychkova, V. M. Polyakov, L. I. Kolesnikova

Application of Impedance Spectroscopy for the Control of the Integrity of In Vitro Models of Barrier Tissues

S. V. Nikulin, T. N. Gerasimenko, S. A. Shilin, G. S. Zakharova, I. N. Gazizov, A. A. Poloznikov, D. A. Sakharov

METHODS

Efficiency and Prospects of Diagnosis of the Functional State of the Dental System

E. A. Solovykh, V. K. Leont’ev, M. O. Zubrikhina, A. I. Molodchenkov

Experimental Study of the Biomechanics of Maxillary Implants under Conditions of Biomechanical Modeling

V. N. Olesova, M. A. Amkhadova, S. A. Zaslavskii, E. E. Olesov, V. R. Shashmurina

Cell Technologies in Biology and Medicine

Application of Adeno-Associated Virus Vectors for Engineering SCF-Containing Extracellular Vesicles of Mesenchymal Stromal Cells

E. S. Zubkova, I. B. Beloglazova, E. G. Evtushenko, A. T. Kopylov, E. K. Shevchenko, K. V. Dergilev, E. I. Ratner, E. V. Parfenova, M. Yu. Men’shikov

Comparative Analysis of Secretome of Human Umbilical Cord- and Bone Marrow-Derived Multipotent Mesenchymal Stromal Cells

Yu. A. Romanov, N. E. Volgina, V. V. Vtorushina, A. Yu. Romanov, T. N. Dugina, N. V. Kabaeva, G. T. Sukhikh

Translated from Kletochnye Tekhnologii v Biologii i Meditsine (Cell Technologies in Biology and Medicine)

Involvement of Actin Filaments in the Cytotoxic Effect of GD2-Specific Antibodies

I. I. Doronin, I. V. Kholodenko, A. A. Zubareva, K. N. Yarygin, S. M. Deev, R. V. Kholodenko

Translated from Kletochnye Tekhnologii v Biologii i Meditsine (Cell Technologies in Biology and Medicine)

Combination of Mesenchymal Stromal Cells and Cardiac Stem Cells in a Multilayer Cell Construct Promotes Activation of Notch Signaling and Initiation of Endothelial Differentiation

E. K. Shevchenko, K. V. Dergilev, Z. I. Tsokolaeva, I. B. Beloglazova, Yu. D. Molokotina, E. V. Parfenova, M. Yu. Men’shikov

Translated from Kletochnye Tekhnologii v Biologii i Meditsine (Cell Technologies in Biology and Medicine)

Effect of Different Regimens of Co-Transplantation of Hemopoietic and Mesenchymal Hemopoietic Stem Cells on the Rates of Hemopoietic Recovery in Laboratory Mice Treated with Cyclophosphamide in Sublethal Doses

V. V. Pavlov, L. N. Pavlova, O. F. Chibisova, V. L. Ivanov, E. I. Selivanova, A. G. Konoplyannikov, L. P. Zhavoronkov

Comparative Analysis of the Effects of Intravenous Administration of Placental Mesenchymal Stromal Cells and Neural Progenitor Cells Derived from Induced Pluripotent Cells on the Course of Acute Ischemic Stroke in Rats

E. A. Cherkashova, V. V. Burunova, T. B. Bukharova, D. D. Namestnikova, I. L. Gubskii, D. I. Salikhova, E. V. Galitsina, G. E. Leonov, V. P. Chekhonin, L. V. Gubskii, S. L. Kisevev, D. V. Goldstein, K. N. Yarygin

Cytotoxic Activity of Peripheral Blood NK Cells towards Trophoblast Cells during Pregnancy

V. A. Mikhailova, D. O. Bazhenov, L. P. Viazmina, A. O. Agnaeva, O. N. Bespalova, S. A. Sel’kov, D. I. Sokolov

Translated from Kletochnye Tekhnologii v Biologii i Meditsine (Cell Technologies in Biology and Medicine)

Effect of Extracellular Vesicles Formed by Multipotent Mesenchymal Stromal Cells on Irradiated Animals

I. B. Alchinova, M. V. Polyakova, E. N. Yakovenko, Yu. S. Medvedeva, I. N. Saburina, M. Yu. Karganov

Translated from Kletochnye Tekhnologii v Biologii i Meditsine (Cell Technologies in Biology and Medicine)

Effect of Polyethylene Terephthalate on Functional Properties of Endothelial and Mesenchymal Cells

A. P. Lykov, O. V. Poveshchenko, M. A. Surovtseva, N. A. Bondarenko, I. I. Kim, A. A. Karpenko, E. A. Pokushalov, A. M. Karaskov

Translated from Kletochnye Tekhnologii v Biologii i Meditsine (Cell Technologies in Biology and Medicine)

Cerebral Blood Flow in SHR Rats after Transplantation of Mesenchymal Stem Cells

I. B. Sokolova, G. I. Lobov

Correction

Correction to: Role of β Cell Precursors in the Regeneration of Insulin-Producing Pancreatic β Cells under the Influence of the Pegylated Form of Glucagon-Like Peptide 1

E. G. Skurikhin, A. V. Pakhomova, A. A. Epanchintsev, O. V. Stronin, N. N. Ermakova, O. V. Pershina, L. A. Ermolaeva, V. A. Krupin, A. I. Kudryashova, V. V. Zhdanov, A. M. Dygai

Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.