Top

Archives of Gynecology and Obstetrics

Published in:

01-05-2019 | Breast Cancer | Gynecologic Oncology

Treatment anxiety in breast cancer patients

Authors: Julian Frederik Wagner, Dörte Lüdders, Friederike Hoellen, Achim Rody, Constanze Banz-Jansen

Published in: Archives of Gynecology and Obstetrics | Issue 5/2019

Abstract

Introduction

The aim of the present study was to determine and evaluate the levels of anxiety of breast cancer patients according to the state of treatment, age and education level, as well as the anxiety potential of certain procedures during breast cancer treatment.

Method

148 breast cancer patients participated in this prospective cohort study and filled out the questionnaires including the Spielberger state-trait-anxiety-inventory, as well as questions based to stress triggering procedures during breast cancer therapy. The testing was accomplished with the Mann–Whitney U test, the significance level was set to 0.05.

Results

Patients who appeared for tumor board decision showed the highest state-anxiety levels (55.79 SD ± 18.73) followed by patients undergoing surgery (50.24 SD ± 13.84). Patients already undergoing chemotherapy had lower state-anxiety levels than the group of all other patients (p = 0.012). Women undergoing chemotherapy showed lower anxiety levels relating to many procedures of breast cancer treatment. The 25% quartile of patients with the highest levels in the trait score showed a significant poorer education level (p = 0.009). Age showed no statistical influence on the anxiety level of breast cancer patients.

Conclusion

Patients with probably high anxiety levels (younger age, low education level, and those appearing for frightening procedures) should receive extra careful clarification and treatment support such as a psycho-oncologist.

American Cancer Society (2013) Cancer facts and figures 2013. American Cancer Society, Atlanta; 036845.pdf, Seite 4,10,11. http://www.cancer.org//groups/content/@epidemiologysurveilance/documents/document/acspc. Accessed 27 Jan 2014

American Cancer Society (2008) Study quantifies risk of breast cancer recurrence. http://www.cancer.org/cancer/news/news/study-quantifies-risk-of-breast-cancer-recurrence. Accessed 03 March 2015

Azim HA, de Azambuja E, Colozza M, Bines J, Piccart MJ (2011) Long-term toxic effects of adjuvant chemotherapy in breast cancer. Ann Oncol 22(9):1939–1947. https://doi.org/10.1093/annonc/mdq683 CrossRefPubMed

Badger TA, Braden CJ, Mishel MH (2001) Depression burden, self-help interventions, and side effect experience in women receiving treatment for breast cancer. Oncol Nurs Forum 28(3):567–574PubMed

Belleau FP, Hagan L, Mâsse B (2001) Effects of an educational intervention on the anxiety of women awaiting mastectomies. Can Oncol Nurs J 11(4):172–180CrossRefPubMed

Burgess C, Cornelius V, Love S, Graham J, Richards M, Ramirez A (2005) Depression and anxiety in women with early breast cancer: five year observational cohort study. BMJ 330(7493):702. https://doi.org/10.1136/bmj.38343.670868.D3 CrossRefPubMedPubMedCentral

Galloway SK, Baker M, Giglio P, Chin S, Madan A, Malcolm R, Borckardt J et al (2012) Depression and anxiety symptoms relate to distinct components of pain experience among patients with breast cancer. Pain Res Treat. https://doi.org/10.1155/2012/851276 CrossRefPubMedPubMedCentral

Herschbach P, Berg P, Dankert A, Duran G, Engst-Hastreiter U, Waadt S, Henrich G et al (2005) Fear of progression in chronic diseases: psychometric properties of the Fear of Progression Questionnaire. J Psychosom Res 58(6):505–511. https://doi.org/10.1016/j.jpsychores.2005.02.007 CrossRefPubMed

Jansen SJT, Otten W, Baas-Thijssen MCM, van de Velde CJH, Nortier JWR, Stiggelbout AM (2005) Explaining differences in attitude toward adjuvant chemotherapy between experienced and inexperienced breast cancer patients. J Clin Oncol 23(27):6623–6630. https://doi.org/10.1200/JCO.2005.07.171 CrossRefPubMed

10.

Julian LJ (2011) Measures of anxiety: State-Trait Anxiety Inventory (STAI), Beck Anxiety Inventory (BAI), and Hospital Anxiety and Depression Scale-Anxiety (HADS-A). Arthritis Care Res 63(Suppl 11):S467–472. https://doi.org/10.1002/acr.20561 CrossRef

11.

Klafta JM, Roizen MF (1996) Current understanding of patients’ attitudes toward and preparation for anesthesia: a review. Anesth Analg 83(6):1314–1321PubMed

12.

Laux L, Glanzmann P, Schaffner P, Spielberger CD (1981) Das State-Trait-Angstinventar. Theoretische Grundlagen und Handanweisung. Beltz Test GmbH, Weinheim

13.

Lim CC, Devi MK, Ang E (2011) Anxiety in women with breast cancer undergoing treatment: a systematic review. Int J Evid-Based Healthc 9(3):215–235. https://doi.org/10.1111/j.1744-1609.2011.00221.x CrossRefPubMed

14.

Liu D-G, Wang S-S, Peng R-J, Qin T, Shi Y-X, Teng X-Y, Yuan Z-Y et al (2011) Interaction of social support and psychological stress on anxiety and depressive symptoms in breast cancer patients. Asian Pac J Cancer Prev 12(10):2523–2529PubMed

15.

Matthey P, Finucane BT, Finegan BA (2001) The attitude of the general public towards preoperative assessment and risks associated with general anesthesia. Can J Anaesth 48(4):333–339. https://doi.org/10.1007/BF03014959 CrossRefPubMed

16.

Miller M, Kearney N (2004) Chemotherapy-related nausea and vomiting—past reflections, present practice and future management. Eur J Cancer Care 13(1):71–81CrossRef

17.

Molassiotis A, Yung HP, Yam BMC, Chan FYS, Mok TSK (2002) The effectiveness of progressive muscle relaxation training in managing chemotherapy-induced nausea and vomiting in Chinese breast cancer patients: a randomised controlled trial. Supportive Care Cancer 10(3):237–246. https://doi.org/10.1007/s00520-001-0329-9 CrossRef

18.

Ortiz J, Wang S, Elayda MA, Tolpin DA (2015) Preoperative patient education: can we improve satisfaction and reduce anxiety? Braz J Anesthesiol 65(1):7–13. https://doi.org/10.1016/j.bjane.2013.07.009 CrossRef

19.

Osborne RH, Elsworth GR, Hopper JL (2003) Age-specific norms and determinants of anxiety and depression in 731 women with breast cancer recruited through a population-based cancer registry. Eur J Cancer (Oxford, England: 1990) 39(6):755–762CrossRef

20.

Robert Koch Institut, Institut für Krebsregisterdaten, 2014/2015 (2017) https://www.krebsdaten.de/Krebs/DE/Content/Krebsarten/Brustkrebs/brustkrebs_node.html

21.

Shannon C, Smith IE (2003) Breast cancer in adolescents and young women. Eur J Cancer (Oxford, England: 1990) 39(18):2632–2642CrossRef

22.

Spielberger CD, Gorsuch RL, Lushene RE (1970) STAI. Manual for the state-trait-anxiety-inventory, Palo Alto

23.

Spielberger CD (1983) Manual for the State-Trait Anxiety Scale. Consulting Psychologists, Palo Alto

24.

Van Esch L, Roukema JA, Van der Steeg AFW, De Vries J (2011) Trait anxiety predicts disease-specific health status in early-stage breast cancer patients. Qual Life Res 20(6):865–873. https://doi.org/10.1007/s11136-010-9830-2 CrossRefPubMedPubMedCentral

25.

Wong CA, Bramwell L (1992) Uncertainty and anxiety after mastectomy for breast cancer. Cancer Nurs 15(5):363–371CrossRefPubMed

Title: Treatment anxiety in breast cancer patients
Authors: Julian Frederik Wagner
Dörte Lüdders
Friederike Hoellen
Achim Rody
Constanze Banz-Jansen
Publication date: 01-05-2019
Publisher: Springer Berlin Heidelberg
Keywords: Breast Cancer
Breast Cancer
Anxiety
Cytostatic Therapy
Published in: Archives of Gynecology and Obstetrics / Issue 5/2019
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI: https://doi.org/10.1007/s00404-018-05038-z

At a glance: The STEP trials

Springer Medicine

Treatment anxiety in breast cancer patients

Abstract

Introduction

Method

Results

Conclusion

At a glance: The STEP trials

Springer Medicine

Abstract

Introduction

Method

Results

Conclusion

Please log in to get access to this content

Other articles of this Issue 5/2019

Compare two different usages of FRD for detecting high-grade cervical lesions and invasive cancer

Splenic artery blood flow as a potential marker for materno-fetal transmission of a primary CMV infection

Effectiveness of the cervical pessary for the prevention of preterm birth in singleton pregnancies with a short cervix: a meta-analysis of randomized trials

The impact of EndoPredict ® on decision making with increasing oncological work experience: can overtreatment be avoided?

Downregulation of miR-4443 and miR-5195-3p in ovarian cancer tissue contributes to metastasis and tumorigenesis

Tumor cell-specific Serpin A1 expression in vulvar squamous cell carcinoma