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European Archives of Oto-Rhino-Laryngology

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10-11-2023 | Breast Cancer | Miscellaneous

The impact of tamoxifen treatment on voice parameters in premenopausal women with breast cancer

Authors: Serdar Ata, Nur Yücel Ekici, Mahmut Büyükşimşek, Timuçin Çil, Berna Bozkurt Duman

Published in: European Archives of Oto-Rhino-Laryngology | Issue 2/2024

Abstract

Objective

The study aims to investigate the estrogen-agonistic effects of tamoxifen on voice parameters in premenopausal women diagnosed with breast cancer.

Methods

A total of 108 premenopausal women were included, segmented into distinct treatment groups and a control group. Objective sound analysis was conducted using robust statistical methods, employing SPSS 25.0 for data analysis.

Results

The study identified a statistically significant reduction in Jitter values across all treatment groups compared to the control group. No significant changes were observed in other voice quality parameters such as F0, Shimmer, NHR, and HNR.

Conclusions

The findings suggest that tamoxifen may have an estrogen-agonistic effect on voice quality, thereby potentially influencing future treatment protocols. This research fills a critical void in existing literature and sets the stage for more comprehensive studies that consider affects of hormonal therapies to voice.

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Title: The impact of tamoxifen treatment on voice parameters in premenopausal women with breast cancer
Authors: Serdar Ata
Nur Yücel Ekici
Mahmut Büyükşimşek
Timuçin Çil
Berna Bozkurt Duman
Publication date: 10-11-2023
Publisher: Springer Berlin Heidelberg
Keywords: Breast Cancer
Breast Cancer
Tamoxifen
Estrogens
Published in: European Archives of Oto-Rhino-Laryngology / Issue 2/2024
Print ISSN: 0937-4477
Electronic ISSN: 1434-4726
DOI: https://doi.org/10.1007/s00405-023-08328-8

Keynote webinar | Spotlight on medication adherence

Springer Medicine

The impact of tamoxifen treatment on voice parameters in premenopausal women with breast cancer

Abstract

Objective

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objective

Methods

Results

Conclusions

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