Published in:
Open Access
01-12-2019 | Breast Cancer | Review
Genetic and molecular biology of breast cancer among Iranian patients
Author:
Meysam Moghbeli
Published in:
Journal of Translational Medicine
|
Issue 1/2019
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Abstract
Abstract
Background, Breast cancer (BC) is one of the leading causes of cancer related deaths in Iran. This high ratio of mortality had a rising trend during the recent years which is probably associated with late diagnosis.
Main body
Therefore it is critical to define a unique panel of genetic markers for the early detection among our population. In present review we summarized all of the reported significant genetic markers among Iranian BC patients for the first time, which are categorized based on their cellular functions.
Conclusions
This review paves the way of introducing a unique ethnic specific panel of diagnostic markers among Iranian BC patients. Indeed, this review can also clarify the genetic and molecular bases of BC progression among Iranians.