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Breast Cancer Research and Treatment

Issue 2/2013

Content (34 Articles)

Preclinical study

Clinicopathological significance of KU70/KU80, a key DNA damage repair protein in breast cancer

Alaa T. Alshareeda, Ola H. Negm, Nada Albarakati, Andrew R. Green, Christopher Nolan, Rebeka Sultana, Srinivasan Madhusudan, Ahmed benHasouna, Paddy Tighe, Ian O. Ellis, Emad A. Rakha

Preclinical study

Micro-computed tomography (Micro-CT): a novel approach for intraoperative breast cancer specimen imaging

Rong Tang, Julliette M. Buckley, Leopoldo Fernandez, Suzanne Coopey, Owen Aftreth, James Michaelson, Mansi Saksena, Lan Lei, Michelle Specht, Michele Gadd, Yukako Yagi, Elizabeth Rafferty, Elena Brachtel, Barbara L. Smith

Preclinical study

Platform comparisons for identification of breast cancers with a BRCA-like copy number profile

Philip C. Schouten, Ewald van Dyk, Linde M. Braaf, Lennart Mulder, Esther H. Lips, Jorma J. de Ronde, Laura Holtman, Jelle Wesseling, Michael Hauptmann, Lodewyk F. A. Wessels, Sabine C. Linn, Petra M. Nederlof

Preclinical study

The impact of cyclin D1 overexpression on the prognosis of ER-positive breast cancers: a meta-analysis

Xiao-Ling Xu, Shu-Zheng Chen, Wei Chen, Wei-Hui Zheng, Xiang-Hou Xia, Hong-Jian Yang, Bo Li, Wei-Min Mao

Preclinical study

DNA promoter hypermethylation profiles in breast duct fluid

Dominique Twelves, Ashutosh Nerurkar, Peter Osin, Tim Dexter, Ann Ward, Gerald P. H. Gui, Clare M. Isacke

Preclinical study

Rank-based predictors for response and prognosis of neoadjuvant taxane-anthracycline-based chemotherapy in breast cancer

Lin Zhang, Chunxiang Hao, Xiaopei Shen, Guini Hong, Hongdong Li, Xianxiao Zhou, ChunYang Liu, Zheng Guo

Preclinical study

Prognostic significance of the tumor-stroma ratio: validation study in node-negative premenopausal breast cancer patients from the EORTC perioperative chemotherapy (POP) trial (10854)

T. J. A. Dekker, C. J. H. van de Velde, G. W. van Pelt, J. R. Kroep, J-P. Julien, V. T. H. B. M. Smit, R. A. E. M. Tollenaar, W. E. Mesker

Preclinical study

FOXP3-positive regulatory T lymphocytes and epithelial FOXP3 expression in synchronous normal, ductal carcinoma in situ, and invasive cancer of the breast

Aseem Lal, Loretta Chan, Sandy DeVries, Koei Chin, Gary K. Scott, Christopher C. Benz, Yunn-Yi Chen, Frederic M. Waldman, E. Shelley Hwang

Preclinical study

Acute inflammation induced by the biopsy of mouse mammary tumors promotes the development of metastasis

Julia Hobson, Phani Gummadidala, Brian Silverstrim, Dore Grier, Janice Bunn, Ted James, Mercedes Rincon

Clinical trial

A phase II study of bevacizumab in combination with vinorelbine and trastuzumab in HER2-positive metastatic breast cancer

N. U. Lin, D. S. Seah, R. Gelman, S. Desantis, E. L. Mayer, S. Isakoff, P. DiPiro, I. E. Krop, S. E. Come, D. Weckstein, E. P. Winer, H. J. Burstein

Open Access Clinical trial

A randomized, phase II, three-arm study of two schedules of ixabepilone or paclitaxel plus bevacizumab as first-line therapy for metastatic breast cancer

Hope S. Rugo, Mario Campone, Dino Amadori, Daniela Aldrighetti, PierFranco Conte, Andrew Wardley, Cristian Villanueva, Michelle Melisko, M. Brent McHenry, David Liu, Francis Lee, Xavier Pivot

Clinical trial

Influence of ABCB1 polymorphisms and docetaxel pharmacokinetics on pathological response to neoadjuvant chemotherapy in breast cancer patients

Pierre Lévy, Joseph Gligorov, Martine Antoine, Keyvan Rezai, Eric Lévy, Frédéric Selle, Pierre Saintigny, François Lokiec, Danielle Avenin, Karine Beerblock, Jean-Pierre Lotz, Jean-François Bernaudin, Anne Fajac

Clinical trial

Shared decision-making in metastatic breast cancer: discrepancy between the expected prolongation of life and treatment efficacy between patients and physicians, and influencing factors

Michael P. Lux, Christian M. Bayer, Christian R. Loehberg, Peter A. Fasching, Michael G. Schrauder, Mayada R. Bani, Lothar Häberle, Anne Engel, Katharina Heusinger, Thorsten Tänzer, Dragan Radosavac, Anton Scharl, Ingo Bauerfeind, Judith Gesslein, Hilde Schulte, Brigitte Overbeck-Schulte, Matthias W. Beckmann, Alexander Hein

Open Access Clinical Trial

A randomized, double-blind, controlled study of exemestane versus anastrozole for the first-line treatment of postmenopausal Japanese women with hormone-receptor-positive advanced breast cancer

Hiroji Iwata, Norikazu Masuda, Shinji Ohno, Yoshiaki Rai, Yasuyuki Sato, Shozo Ohsumi, Satoshi Hashigaki, Yoshinori Nishizawa, Masahiro Hiraoka, Tadaoki Morimoto, Hironobu Sasano, Toshiaki Saeki, Shinzaburo Noguchi

Epidemiology

Risk factors for non-invasive and invasive local recurrence in patients with ductal carcinoma in situ

Laura C. Collins, Ninah Achacoso, Reina Haque, Larissa Nekhlyudov, Suzanne W. Fletcher, Charles P. Quesenberry Jr., Stuart J. Schnitt, Laurel A. Habel

Epidemiology

Adiponectin pathway polymorphisms and risk of breast cancer in African Americans and Hispanics in the Women’s Health Initiative

Virginia G. Kaklamani, Thomas J. Hoffmann, Timothy A. Thornton, Geoffrey Hayes, Rowan Chlebowski, Linda Van Horn, Christos Mantzoros

Epidemiology

Pretreatment levels of circulating Th1 and Th2 cytokines, and their ratios, are associated with ER-negative and triple negative breast cancers

Chi-Chen Hong, Song Yao, Susan E. McCann, Ree Y. Dolnick, Paul K. Wallace, Zhihong Gong, Lei Quan, Kelvin P. Lee, Sharon S. Evans, Elizabeth A. Repasky, Stephen B. Edge, Christine B. Ambrosone

Epidemiology

Time-dependent resource use and costs associated with different states of disease in patients diagnosed with HER-2-positive metastatic breast cancer

G. W. J. Frederix, J. L. Severens, A. M. Hövels, J. G. C. van Hasselt, J. A. M. Raaijmakers, J. H. M. Schellens

Epidemiology

Black race as a prognostic factor in triple-negative breast cancer patients treated with breast-conserving therapy: a large, single-institution retrospective analysis

Carmen A. Perez, Zachary S. Zumsteg, Gaorav Gupta, Monica Morrow, Brittany Arnold, Sujata M. Patil, Tiffany A. Traina, Mark E. Robson, Yong H. Wen, Beryl McCormick, Simon N. Powell, Alice Y. Ho

Epidemiology

Social networks, social support mechanisms, and quality of life after breast cancer diagnosis

Candyce H. Kroenke, Marilyn L. Kwan, Alfred I. Neugut, Isaac J. Ergas, Jaime D. Wright, Bette J. Caan, Dawn Hershman, Lawrence H. Kushi

Epidemiology

Postdiagnosis supplement use and breast cancer prognosis in the After Breast Cancer Pooling Project

Elizabeth M. Poole, XiaoOu Shu, Bette J. Caan, Shirley W. Flatt, Michelle D. Holmes, Wei Lu, Marilyn L. Kwan, Sarah J. Nechuta, John P. Pierce, Wendy Y. Chen

Open Access Epidemiology

Ki-67 is a prognostic parameter in breast cancer patients: results of a large population-based cohort of a cancer registry

E. C. Inwald, M. Klinkhammer-Schalke, F. Hofstädter, F. Zeman, M. Koller, M. Gerstenhauer, O. Ortmann

Epidemiology

Influence of CYP2D6-genotype on tamoxifen efficacy in advanced breast cancer

Jennifer Karle, Juliane Bolbrinker, Silvia Vogl, Reinhold Kreutz, Carsten Denkert, Jan Eucker, Manfred Wischnewsky, Kurt Possinger, Anne C. Regierer

Epidemiology

Simplifying clinical use of the genetic risk prediction model BRCAPRO

Swati Biswas, Philamer Atienza, Jonathan Chipman, Kevin Hughes, Angelica M. Gutierrez Barrera, Christopher I. Amos, Banu Arun, Giovanni Parmigiani

Epidemiology

Patient–physician interaction and quality of life in recently diagnosed breast cancer patients

Marilyn L. Kwan, Emily K. Tam, Isaac J. Ergas, David H. Rehkopf, Janise M. Roh, Marion M. Lee, Carol P. Somkin, Anita L. Stewart, Lawrence H. Kushi

Brief Report

Germline mutations in NF1 and BRCA1 in a family with neurofibromatosis type 1 and early-onset breast cancer

Berta Campos, Judith Balmaña, Josep Gardenyes, Irene Valenzuela, Oscar Abad, Pere Fàbregas, Víctor Volpini, Orland Díez

Brief Report

Cognitive function in older women with breast cancer treated with standard chemotherapy and capecitabine on Cancer and Leukemia Group B 49907

Rachel A. Freedman, Brandelyn Pitcher, Nancy L. Keating, Karla V. Ballman, Jeanne Mandelblatt, Alice B. Kornblith, Gretchen G. Kimmick, Arti Hurria, Eric P. Winer, Clifford A. Hudis, Harvey Jay Cohen, Hyman B. Muss

Letter to the Editor

What is the clinical significance of the volume of tissue excised in ROLL?

Muneer Ahmed, Michael Douek

Webinar | 19-02-2024 | 17:30 (CET)

Keynote webinar | Spotlight on antibody–drug conjugates in cancer

Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.

Dr. Véronique Diéras
Prof. Fabrice Barlesi
Developed by: Springer Medicine