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Published in: BMC Infectious Diseases 1/2016

Open Access 01-12-2016 | Case report

Breast abscess due to Salmonella Typhimurium in a patient with rheumatoid arthritis: a case report

Authors: Irmak Baran, Neriman Aksu, Altan Aksoy

Published in: BMC Infectious Diseases | Issue 1/2016

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Abstract

Background

This is the first report of breast abscess due to Salmonella enterica serotype Typhimurium. Staphylococcus aureus is known as the most common cause of breast abscess. Salmonella spp. may occasionally form localized abscesses after dissemination to various organ systems following a bacteraemia. But breast abscess related to Salmonella spp is a very rare complication.

Case presentation

A 43-year-old female patient referred to our hospital with a lump, fever and mild pain in her breast. The patient was not pregnant or lactating at that time. She had a history of rheumatoid arthritis for 5 years and was under immunosuppressive therapy. Ultrasonography of the breast revealed an abscess. The abscess was drained and sent for culture to medical microbiology laboratory. The microorganism was identified as Salmonella enterica serotype Typhimurium and found to be sensitive to all antibiotics tested. The patient was cured after surgical debridement and antibiotic therapy. The abscess did not recur again.

Conclusions

This case is presented to draw attention to non-typhoidal Salmonella as rare causes of breast abscess and submission of specimens to the microbiology laboratory for accurate diagnosis and treatment especially in patients with underlying immunosuppressive diseases.
Literature
1.
go back to reference Edelstein H. Breast abscess due to Salmonella serogroup B, serotype reading, in a young nonpuerperal woman. Clin Infect Dis. 1993;17:951–2.CrossRefPubMed Edelstein H. Breast abscess due to Salmonella serogroup B, serotype reading, in a young nonpuerperal woman. Clin Infect Dis. 1993;17:951–2.CrossRefPubMed
2.
go back to reference Sudhaharan S, Padmaja K, Solanki R, Lakshmi V, Umabala P, Aparna B. Extra-intestinal salmonellosis in a tertiary care center in South India. J Infect Dev Ctries. 2014;8:831–7.CrossRefPubMed Sudhaharan S, Padmaja K, Solanki R, Lakshmi V, Umabala P, Aparna B. Extra-intestinal salmonellosis in a tertiary care center in South India. J Infect Dev Ctries. 2014;8:831–7.CrossRefPubMed
4.
go back to reference Fernando S, Molland JG, Gottlieb T. Failure of oral antibiotic therapy, including azithromycin, in the treatment of a recurrent breast abscess caused by Salmonella enterica serotype Paratyphi A. Pathog Glob Health. 2012;106:366–9.CrossRefPubMedPubMedCentral Fernando S, Molland JG, Gottlieb T. Failure of oral antibiotic therapy, including azithromycin, in the treatment of a recurrent breast abscess caused by Salmonella enterica serotype Paratyphi A. Pathog Glob Health. 2012;106:366–9.CrossRefPubMedPubMedCentral
5.
go back to reference Jayakumar K, Appalaraju B, Govindan VK. An atypical presentation of Salmonella typhi - a casereport. Indian J Med Microbiol. 2003;21:211–2.PubMed Jayakumar K, Appalaraju B, Govindan VK. An atypical presentation of Salmonella typhi - a casereport. Indian J Med Microbiol. 2003;21:211–2.PubMed
6.
go back to reference Sood S. Breast abscess by Salmonella Paratyphi A: case report and literature review. J Clin Diagn Res. 2015;9:DD03–4.PubMedPubMedCentral Sood S. Breast abscess by Salmonella Paratyphi A: case report and literature review. J Clin Diagn Res. 2015;9:DD03–4.PubMedPubMedCentral
7.
go back to reference Brncic N, Gorup L, Strcic M, Abram M, Mustac E. Breast abscess in a man due to Salmonella enterica serotype Enteritidis. J Clin Microbiol. 2012;50:192–3.CrossRefPubMedPubMedCentral Brncic N, Gorup L, Strcic M, Abram M, Mustac E. Breast abscess in a man due to Salmonella enterica serotype Enteritidis. J Clin Microbiol. 2012;50:192–3.CrossRefPubMedPubMedCentral
8.
go back to reference Al Benwan K, Al Mulla A, Izumiya H, Albert MJ. Erythema nodosum and bilateral breast abscesses due to Salmonella enterica serotype Poona. J Clin Microbiol. 2010;48:3786–7.CrossRefPubMedPubMedCentral Al Benwan K, Al Mulla A, Izumiya H, Albert MJ. Erythema nodosum and bilateral breast abscesses due to Salmonella enterica serotype Poona. J Clin Microbiol. 2010;48:3786–7.CrossRefPubMedPubMedCentral
9.
go back to reference Pastagia M, Jenkins SG. Salmonella neck abscess as an opportunistic infection in diabetes mellitus. Case Rep Infect Dis. 2013;2013:708419.PubMedPubMedCentral Pastagia M, Jenkins SG. Salmonella neck abscess as an opportunistic infection in diabetes mellitus. Case Rep Infect Dis. 2013;2013:708419.PubMedPubMedCentral
10.
go back to reference Singh S, Pandya Y, Rathod J, Trivedi S. Bilateral breast abscess: a rare complication of enteric fever. Indian J Med Microbiol. 2009;27:69–70.PubMed Singh S, Pandya Y, Rathod J, Trivedi S. Bilateral breast abscess: a rare complication of enteric fever. Indian J Med Microbiol. 2009;27:69–70.PubMed
11.
go back to reference Banu A, Hassan MM, Anand M. Breast abscess: sole manifestation of Salmonella typhi infection. Indian J Med Microbiol. 2013;31:94–5.CrossRefPubMed Banu A, Hassan MM, Anand M. Breast abscess: sole manifestation of Salmonella typhi infection. Indian J Med Microbiol. 2013;31:94–5.CrossRefPubMed
12.
go back to reference Listing J, Gerhold K, Zink A. The risk of infections associated with rheumatoid arthritis, with its comorbidity and treatment. Rheumatology (Oxford). 2013;52:53–61.CrossRef Listing J, Gerhold K, Zink A. The risk of infections associated with rheumatoid arthritis, with its comorbidity and treatment. Rheumatology (Oxford). 2013;52:53–61.CrossRef
13.
go back to reference Koetz K, Bryl E, Spickschen K, O’Fallon WM, Goronzy JJ, Weyand CM. T cell homeostasis in patients with rheumatoid arthritis. Proc Natl Acad Sci U S A. 2000;97:9203–8.CrossRefPubMedPubMedCentral Koetz K, Bryl E, Spickschen K, O’Fallon WM, Goronzy JJ, Weyand CM. T cell homeostasis in patients with rheumatoid arthritis. Proc Natl Acad Sci U S A. 2000;97:9203–8.CrossRefPubMedPubMedCentral
14.
go back to reference Schönland SO, Lopez C, Widmann T, Zimmer J, Bryl E, Goronzy JJ, Weyand CM. Premature telomeric loss in rheumatoid arthritis is genetically determined and involves both myeloid and lymphoid cell lineages. Proc Natl Acad Sci U S A. 2003;100:13471–6.CrossRefPubMedPubMedCentral Schönland SO, Lopez C, Widmann T, Zimmer J, Bryl E, Goronzy JJ, Weyand CM. Premature telomeric loss in rheumatoid arthritis is genetically determined and involves both myeloid and lymphoid cell lineages. Proc Natl Acad Sci U S A. 2003;100:13471–6.CrossRefPubMedPubMedCentral
15.
go back to reference Schmidt D, Goronzy JJ, Weyand CM. CD4+ CD7–CD28- T cells are expanded in rheumatoid arthritis and are characterized by autoreactivity. J Clin Invest. 1996;97:2027–37.CrossRefPubMedPubMedCentral Schmidt D, Goronzy JJ, Weyand CM. CD4+ CD7–CD28- T cells are expanded in rheumatoid arthritis and are characterized by autoreactivity. J Clin Invest. 1996;97:2027–37.CrossRefPubMedPubMedCentral
16.
go back to reference Wagner UG, Koetz K, Weyand CM, Goronzy JJ. Perturbation of the T cell repertoire in rheumatoid arthritis. Proc Natl Acad Sci U S A. 1998;95:14447–52.CrossRefPubMedPubMedCentral Wagner UG, Koetz K, Weyand CM, Goronzy JJ. Perturbation of the T cell repertoire in rheumatoid arthritis. Proc Natl Acad Sci U S A. 1998;95:14447–52.CrossRefPubMedPubMedCentral
19.
go back to reference Singh G, Dasgupta M, Gautam V, Behera A, Ray P. Bilateral breast abscesses due to Salmonella Enterica Serotype Typhi. J Glob Infect Dis. 2011;3:402–4.CrossRefPubMedPubMedCentral Singh G, Dasgupta M, Gautam V, Behera A, Ray P. Bilateral breast abscesses due to Salmonella Enterica Serotype Typhi. J Glob Infect Dis. 2011;3:402–4.CrossRefPubMedPubMedCentral
20.
go back to reference Lalitha MK, John R. Unusual manifestations of salmonellosis--a surgical problem. Q J Med. 1994;87:301–9.PubMed Lalitha MK, John R. Unusual manifestations of salmonellosis--a surgical problem. Q J Med. 1994;87:301–9.PubMed
21.
go back to reference Delori M, Abgueguen P, Chennebault JM, Pichard E, Fanello S. Breast abscess with Salmonella typhi and review of the literature. J Gynecol Obstet Biol Reprod (Paris). 2007;36:709–12.CrossRef Delori M, Abgueguen P, Chennebault JM, Pichard E, Fanello S. Breast abscess with Salmonella typhi and review of the literature. J Gynecol Obstet Biol Reprod (Paris). 2007;36:709–12.CrossRef
22.
go back to reference Mahajan RK, Duggal S, Chande DS, Duggal N, Hans C, Chaudhry R. Salmonella enterica serotype Typhi from a case of breast abscess. J Commun Dis. 2007;39:201–4.PubMed Mahajan RK, Duggal S, Chande DS, Duggal N, Hans C, Chaudhry R. Salmonella enterica serotype Typhi from a case of breast abscess. J Commun Dis. 2007;39:201–4.PubMed
23.
go back to reference Vattipally V, Thatigotla B, Nagpal K, Saraiya R, Henry M, Shah AK, Cosgrove J. Salmonella typhi breast abscess: an uncommon manifestation of an uncommon disease in the United States. Am Surg. 2011;77:E133–5.PubMed Vattipally V, Thatigotla B, Nagpal K, Saraiya R, Henry M, Shah AK, Cosgrove J. Salmonella typhi breast abscess: an uncommon manifestation of an uncommon disease in the United States. Am Surg. 2011;77:E133–5.PubMed
24.
go back to reference Kumar ES, Selvam RE, Ramesh SS. Salmonella enterica serovar Typhi in breast abscess: a case report. Indian J Pathol Microbiol. 2012;55:608–9.CrossRefPubMed Kumar ES, Selvam RE, Ramesh SS. Salmonella enterica serovar Typhi in breast abscess: a case report. Indian J Pathol Microbiol. 2012;55:608–9.CrossRefPubMed
25.
go back to reference Siddesh G, Sumana MN. A case of breast abscess due to Salmonella Paratyphi A. Int J Health Allied Sci. 2012;1:109–11.CrossRef Siddesh G, Sumana MN. A case of breast abscess due to Salmonella Paratyphi A. Int J Health Allied Sci. 2012;1:109–11.CrossRef
26.
go back to reference Ghadage DP, Wankhade AB, Mali RJ, Bhore AV. Recurrent breast abscess due to Salmonella Paratyphi A: an unusual case. Int J Res Med Sci. 2014;2:1236–8.CrossRef Ghadage DP, Wankhade AB, Mali RJ, Bhore AV. Recurrent breast abscess due to Salmonella Paratyphi A: an unusual case. Int J Res Med Sci. 2014;2:1236–8.CrossRef
27.
go back to reference Elumalai S, Seetharaman S. Molecular analysis of fluoroquinolone resistance in Salmonella enterica serovar Typhi from a breast abscess case. Indian J Pathol Microbiol. 2016;59:261.CrossRefPubMed Elumalai S, Seetharaman S. Molecular analysis of fluoroquinolone resistance in Salmonella enterica serovar Typhi from a breast abscess case. Indian J Pathol Microbiol. 2016;59:261.CrossRefPubMed
28.
go back to reference Razeq JH, Glenn A, Thomas G, Sholes A. First human case of Salmonella enterica serotype Landwasser recovered from breast fluid. J Clin Microbiol. 2000;38:4300.PubMedPubMedCentral Razeq JH, Glenn A, Thomas G, Sholes A. First human case of Salmonella enterica serotype Landwasser recovered from breast fluid. J Clin Microbiol. 2000;38:4300.PubMedPubMedCentral
29.
go back to reference Mohamed M, Asnis D. A geriatric breast abscess due to Salmonella enteritidis. Clin Microbiol. 2014;3:5. Mohamed M, Asnis D. A geriatric breast abscess due to Salmonella enteritidis. Clin Microbiol. 2014;3:5.
Metadata
Title
Breast abscess due to Salmonella Typhimurium in a patient with rheumatoid arthritis: a case report
Authors
Irmak Baran
Neriman Aksu
Altan Aksoy
Publication date
01-12-2016
Publisher
BioMed Central
Published in
BMC Infectious Diseases / Issue 1/2016
Electronic ISSN: 1471-2334
DOI
https://doi.org/10.1186/s12879-016-1659-z

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