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01-12-1999 | Paper Report

BRCA1 and estrogen receptor signaling

Author: Michael Davies

Published in: Breast Cancer Research | Issue 1/1999

Excerpt

Mutations of BRCA1 confer increased risk for breast, ovarian, and prostatic cancers, but it is unclear why the mutations are associated with these particular tumor types. Estrogen stimulation of mammary epithelial cells via estrogen receptor (ER) is thought to promote breast cancer. …

Fan S, Wang J, Yuan R, Ma Y, Meng Q, Erdos MR, Pestell RG, Yuan F, Auborn KJ, Goldberg ID, Rosen EM: BRCA1 inhibition of estrogen receptor signaling in transfected cells. Science. 1999, 284: 1354-1356.CrossRefPubMed

Title: BRCA1 and estrogen receptor signaling
Author: Michael Davies
Publication date: 01-12-1999
Publisher: BioMed Central
Published in: Breast Cancer Research / Issue 1/1999
Electronic ISSN: 1465-542X
DOI: https://doi.org/10.1186/bcr-1999-66580

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