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Published in: BMC Infectious Diseases 1/2021

Open Access 01-12-2021 | Bone Defect | Case report

First case of periprosthetic joint infection due to Clostridioides difficile in China

Authors: Yang Song, Hong Yi Shao, Xiang Cheng, Yu Guo

Published in: BMC Infectious Diseases | Issue 1/2021

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Abstract

Background

Clostridioides difficile usually causes intestinal infections. However, a 75-year-old lady had a periprosthetic joint infection due to this microorganism. We report a C. difficile infection of a prosthetic hip joint. Such an infection is rarely reported around the world.

Case presentation

The elder female patient presented with a 2-year history of right hip pain with movement restriction. Her right leg was shorter than another. The skin around the right hip joint was red and swollen without sinus. Her lab test result showed elevator ESR and CRP. Her X-ray film showed a massive bone defect. The patient had a total hip arthroplasty 16 years ago and had a revision 5 years ago. During this hospitalization, her cultures of the synovial fluid and tissue repeatedly grew C. difficile. She improved following two-stage revision surgery and antibiotic treatment. The patient has no recurrence of infection after a one-year follow-up.

Conclusion

A rapid and accurate sample collection is significant for culture results, making an outstanding contribution to the successful treatment.
Literature
7.
go back to reference McCarthy J, Stingemore N. Clostridium difficile infection of a prosthetic joint presenting 12 months after antibiotic-associated diarrhea. J Inf Secur. 1999;39(1):94–6. McCarthy J, Stingemore N. Clostridium difficile infection of a prosthetic joint presenting 12 months after antibiotic-associated diarrhea. J Inf Secur. 1999;39(1):94–6.
15.
go back to reference Jorgensen JH, Pfaller MA. Manual of Clinical Microbiology (M). ASM Press. 2015;1:950–2. Jorgensen JH, Pfaller MA. Manual of Clinical Microbiology (M). ASM Press. 2015;1:950–2.
18.
go back to reference McDonald LC, Gerding DN, Johnson S, Bakken JS, Carroll KC, Coffin SE, et al. Clinical practice guidelines for Clostridium difficile infection in adults and children: 2017 update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA). Clin Infect Dis. 2018;66(7):e1–e48. https://doi.org/10.1093/cid/cix1085.CrossRefPubMedPubMedCentral McDonald LC, Gerding DN, Johnson S, Bakken JS, Carroll KC, Coffin SE, et al. Clinical practice guidelines for Clostridium difficile infection in adults and children: 2017 update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA). Clin Infect Dis. 2018;66(7):e1–e48. https://​doi.​org/​10.​1093/​cid/​cix1085.CrossRefPubMedPubMedCentral
Metadata
Title
First case of periprosthetic joint infection due to Clostridioides difficile in China
Authors
Yang Song
Hong Yi Shao
Xiang Cheng
Yu Guo
Publication date
01-12-2021
Publisher
BioMed Central
Published in
BMC Infectious Diseases / Issue 1/2021
Electronic ISSN: 1471-2334
DOI
https://doi.org/10.1186/s12879-021-06171-y

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