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International Archives of Occupational and Environmental Health

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01-11-2012 | Original Article

Blood cadmium and moderate-to-severe glomerular dysfunction in Korean adults: analysis of KNHANES 2005–2008 data

Authors: Jun-Pyo Myong, Hyoung-Ryoul Kim, Dean Baker, BongKyoo Choi

Published in: International Archives of Occupational and Environmental Health | Issue 8/2012

Abstract

Purpose

The objective of this study was to evaluate the association between blood cadmium (Cd) and moderate-to-severe glomerular dysfunction in a Korean population using a representative sample.

Methods

A cross-sectional study was used to evaluate the association between blood Cd and glomerular dysfunction. Based on the Korean National Health and Nutrition Examination Survey (2005–2008), individual blood Cd was measured in 2,992 adults, aged between 20 and 65.

Results

After adjusting for survey years, age, sociodemographic factors, and health behaviors, the odds ratio for moderate-to-severe glomerular dysfunction (<60 mL/min per 1.73 m²) was 1.97 (95% CI: 1.28–3.07) when comparing the highest with the lowest blood Cd quartile in Korean women. However, in Korean men, there was no association between blood Cd and moderate-to-severe glomerular dysfunction.

Conclusions

These findings support the consideration of Cd as a risk factor for glomerular dysfunction in the female population. Furthermore, environmental heavy metal monitoring and an institutional strategy should be implemented to reduce Cd exposure in the general population.

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Title: Blood cadmium and moderate-to-severe glomerular dysfunction in Korean adults: analysis of KNHANES 2005–2008 data
Authors: Jun-Pyo Myong
Hyoung-Ryoul Kim
Dean Baker
BongKyoo Choi
Publication date: 01-11-2012
Publisher: Springer-Verlag
Published in: International Archives of Occupational and Environmental Health / Issue 8/2012
Print ISSN: 0340-0131
Electronic ISSN: 1432-1246
DOI: https://doi.org/10.1007/s00420-012-0737-9

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Blood cadmium and moderate-to-severe glomerular dysfunction in Korean adults: analysis of KNHANES 2005–2008 data

Abstract

Purpose

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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