Published in:
01-01-2015 | Urology - Original Paper
Bladder capacity in kidney transplant patients with end-stage renal disease
Published in: International Urology and Nephrology | Issue 1/2015
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Introduction
This study evaluated the clinical factors that influence bladder capacity and lower urinary tract dysfunction (LUTD) following kidney transplantation (KT) in end-stage renal disease (ESRD) patients.
Materials and methods
Data were analyzed in ESRD patients who underwent KT between January 2011 and January 2013. The analyzed pre-KT parameters include bladder capacity, vesicoureteral reflux (VUR), postvoid residual urine (PVR), micturition frequency, and voiding volume. Associations between pre-KT parameters, small bladder capacity (<100 cc), and parameters that influence the development of LUTD were also evaluated. LUTD after KT was defined as voiding symptoms that lasted >1 month and required specific treatment.
Results
In total, 622 ESRD patients required KT. The mean age and dialysis duration were 43.9 ± 11.2 years and 59.4 ± 60.7 months. The mean bladder capacity before KT was 300.1 ± 149.8 mL, and 14 % of patients were diagnosed with small bladder capacity. VUR and PVR were observed in 110 (17.5 %) and 83 (13.6 %) patients. Factors associated with small bladder capacity included long-term dialysis, presence of VUR, and PVR (p < 0.001, p = 0.004, p = 0.003). After KT, 31 patients (4.9 %) needed treatment due to LUTD. Factors associated with the development of LUTD included age, VUR, and PVR (p = 0.001 p = 0.034, p < 0.001). Bladder capacity did not affect LUTD after KT.
Conclusion
ESRD patients on long-term dialysis will likely have small bladder capacity and VUR; however, bladder capacity itself is not related to the occurrence of LUTD after KT.