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AIDS Research and Therapy
Published in: AIDS Research and Therapy 1/2007

Open Access 01-12-2007 | Case report

BK virus associated meningoencephalitis in an AIDS patient treated with HAART

Authors: José E Vidal, Maria C Fink, Filiberto Cedeno-Laurent, Serena Delbue, Pasquale Ferrante, Rafi F Dauar, Francisco Bonasser Filho, Roberta Schiavon Nogueira, Eduardo E Calore, Claudio S Pannuti, J Roberto Trujillo, Augusto C Penalva de Oliveira

Published in: AIDS Research and Therapy | Issue 1/2007

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Abstract

A severely immune-suppressed AIDS patient was suspected of suffering from BK virus (BKV) meningoencephalitis, after being studied for common causes of neurological complications of co-infectious origin. Polymerase chain reaction (PCR) and sequence analysis of cerebrospinal fluid and brain samples, confirmed the presence of BKV. His clinical condition improved along with the regression of brain lesions, after modifications on his antiretroviral regime. Five months after discharge, the patient was readmitted because of frequent headaches, and a marked inflammatory reaction was evidenced by a new magnetic resonance imaging (MRI). The symptoms paralleled a rising CD4+ lymphocyte count, and immune reconstitution syndrome was suspected. This is the first non-postmortem report of BKV meningoencephalitis in an AIDS patient, showing clinical and radiographic improvement solely under HAART.
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Metadata
Title
BK virus associated meningoencephalitis in an AIDS patient treated with HAART
Authors
José E Vidal
Maria C Fink
Filiberto Cedeno-Laurent
Serena Delbue
Pasquale Ferrante
Rafi F Dauar
Francisco Bonasser Filho
Roberta Schiavon Nogueira
Eduardo E Calore
Claudio S Pannuti
J Roberto Trujillo
Augusto C Penalva de Oliveira
Publication date
01-12-2007
Publisher
BioMed Central
Published in
AIDS Research and Therapy / Issue 1/2007
Electronic ISSN: 1742-6405
DOI
https://doi.org/10.1186/1742-6405-4-13

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