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International Urogynecology Journal

Published in:

01-10-2012 | Original Article

Biomechanical effects of polyglecaprone fibers in a polypropylene mesh after abdominal and rectovaginal implantation in a rabbit

Authors: Yves Ozog, Edoardo Mazza, Dirk De Ridder, Jan Deprest

Published in: International Urogynecology Journal | Issue 10/2012

Abstract

Introduction and hypothesis

To investigate the biomechanical effects of polyglecaprone fibers in lightweight meshes implanted into the vaginal and abdominal wall of parous rabbits.

Methods

New Zealand White rabbits (n = 24) were implanted with polypropylene meshes (32 g/m²), with (Prolift plus M, n = 12) or without (Prolift minus M, n = 12) polyglecaprone fibers. Following implantation in the posterior vaginal and abdominal wall, local side effects were evaluated and explants underwent uniaxial tensiometry after 120 and 180 days.

Results

The vaginal extrusion rate was at least 50 %, coinciding with a minimum of 20 % of contraction. There were no measurable effects of the addition of polyglecaprone on tensiometric strength and compliance in abdominal explants.

Conclusions

The addition of polyglecaprone fibers did not compromise the biomechanical properties nor did it prevent vaginal extrusion and contraction. The latter as well as some other limitations preclude the rabbit vagina to be a suitable model for biomechanical testing.

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Title: Biomechanical effects of polyglecaprone fibers in a polypropylene mesh after abdominal and rectovaginal implantation in a rabbit
Authors: Yves Ozog
Edoardo Mazza
Dirk De Ridder
Jan Deprest
Publication date: 01-10-2012
Publisher: Springer-Verlag
Published in: International Urogynecology Journal / Issue 10/2012
Print ISSN: 0937-3462
Electronic ISSN: 1433-3023
DOI: https://doi.org/10.1007/s00192-012-1739-6

At a glance: The STEP trials

Springer Medicine

Biomechanical effects of polyglecaprone fibers in a polypropylene mesh after abdominal and rectovaginal implantation in a rabbit

Abstract

Introduction and hypothesis

Methods

Results

Conclusions

At a glance: The STEP trials

Springer Medicine

Abstract

Introduction and hypothesis

Methods

Results

Conclusions

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