Published in:
Open Access
01-12-2014 | Meeting abstract
Biological therapies in monogenic autoinflammatory diseases: long-term efficacy and safety
Authors:
Maria A Pelagatti, Alessandro Cattoni, Carmelo Rizzari
Published in:
Italian Journal of Pediatrics
|
Special Issue 1/2014
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Excerpt
Autoinflammatory diseases (AIDs) represent a group of monogenic disorders, related to mutations in genes encoding proteins involved in the regulation of inflammatory responses. The aims of therapy in AIDs patients are controlling disease activity, improving patient’s quality of life and preventing long-term complications. Biological agents have recently changed the natural history and the prognosis of AIDs. According to a pathogenetic criterium, they can be classified as: …