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01-01-2017

Best options for preoperative biliary drainage in patients with Klatskin tumors

Authors: Jung Hyun Jo, Moon Jae Chung, Dai Hoon Han, Jeong Youp Park, Seungmin Bang, Seung Woo Park, Si Young Song, Jae Bock Chung

Published in: Surgical Endoscopy | Issue 1/2017

Abstract

Summary background data

Operative treatment combined with PBD has been established as a safe management strategy for Klatskin tumors. However, controversy exists regarding the preferred technique for PBD among percutaneous transhepatic biliary drainage (PTBD), endoscopic biliary stenting (EBS), and endoscopic nasobiliary drainage (ENBD). This study aimed to identify the best technique for preoperative biliary drainage (PBD) in Klatskin tumor patients.

Methods

This study evaluated 98 Klatskin tumor patients who underwent PBD prior to operation with a curative aim between 2005 and 2012. The PTBD, EBS, and ENBD groups included 43, 42, and 13 patients, respectively. Baseline characteristics, technical success rate, complications of PBD, and surgical outcomes were compared.

Results

Initial technical success rates (97.3 %, PTBD; 90.2 %, endoscopic methods, including EBS and ENBD) and mean duration until biliary decompression (31.0, PTBD; 28.7, EBS; 35.8 days, ENBD) were not significantly different between the groups. Total frequency of complications did not significantly differ between the EBS group (42.9 %) and the PTBD (27.9 %, p = 0.149) and ENBD (15.4 %, p = 0.072) groups. The ENBD group showed a significantly higher rate of conversion to other methods (76.9 %) than the PTBD (4.7 %, p < 0.0001) and EBS (35.7 %, p = 0.009) groups.

Conclusions

PTBD, EBS, and ENBD showed comparable results regarding initial technical success rates, complication rates, and surgical outcomes. As Klatskin tumor patients must undergo PBD prior to 3 weeks before surgery, PTBD and ENBD are uncomfortable and disadvantageous in terms of compliance. EBS was the most suitable method for initial PBD in terms of compliance among Klatskin tumor patients.

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Title: Best options for preoperative biliary drainage in patients with Klatskin tumors
Authors: Jung Hyun Jo
Moon Jae Chung
Dai Hoon Han
Jeong Youp Park
Seungmin Bang
Seung Woo Park
Si Young Song
Jae Bock Chung
Publication date: 01-01-2017
Publisher: Springer US
Published in: Surgical Endoscopy / Issue 1/2017
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI: https://doi.org/10.1007/s00464-016-4993-8

At a glance: The STEP trials

Springer Medicine

Best options for preoperative biliary drainage in patients with Klatskin tumors

Abstract

Summary background data

Methods

Results

Conclusions

At a glance: The STEP trials

Springer Medicine

Abstract

Summary background data

Methods

Results

Conclusions

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