Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on medication adherence

LIVE: Thursday 27th June 2024, 18:00-19:30 (CEST)
Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.
ADVANCED SEARCH
Log in
Top
Health and Quality of Life Outcomes
Published in: Health and Quality of Life Outcomes 1/2016

Open Access 01-12-2016 | Research

“Back to the future”: Influence of beliefs regarding the future on TTO answers

Authors: F. E. van Nooten, N.J.A. van Exel, D. Eriksson, W.B.F. Brouwer

Published in: Health and Quality of Life Outcomes | Issue 1/2016

Login to get access

Abstract

Background

A common approach to obtain health state valuations is the time-tradeoff (TTO) method. Much remains unknown regarding the influence of responder characteristics on TTO answers. The objective of this study is to increase understanding of the influence that beliefs regarding future health and death, as well as desires to witness certain life events, have on respondents’ health state valuations.

Methods

An online survey was designed, including three TTO questions using a 10 year timeframe. Moreover, respondents completed demographic questions, the Health-Risk Attitude Scale (HRAS), the Expectations Regarding Aging (ERA) questionnaire, questions about beliefs regarding future health (i.e. life expectancy) and death (i.e. fear of death, belief in life after death and opinion about euthanasia), and about important life events taking place within the TTO timeframe. Regression analyses were performed in order to assess the influence of these different variables.

Results

One thousand sixty-seven respondents were included in the analyses. The following variables were significantly associated with years traded off: ERA mental health (decrease), ERA physical health (increase), HRAS (increase), support for euthanasia (increase), fear of death (decrease) and consideration of an important life event (decrease). The explained variance of the final model was low (0.08).

Conclusion

TTO responses may be influenced by considerations of future health, including life events and attitudes regarding health risks and death. Further investigation of TTO responses remains warranted.
Appendix
Available only for authorised users
Literature
1.
Torrance GW, Feeny D. Utilities and quality-adjusted life years. Int J Technol Assess Health Care. 1989;5(4):559–75.PubMedCrossRef
2.
Greiner W, Claes C, Busschbach JJ, von der Schulenburg JM. Validating the EQ-5D with time trade off for the German population. Eur J Health Econ. 2005;6(2):124–30.PubMedCrossRef
3.
Scalone L, Cortesi PA, Ciampichini R, Belisari A, D’Angiolella LS, Cesana G, et al. Italian population-based values of EQ-5D health states. Value Health. 2013;16(5):814–22.PubMedCrossRef
4.
Torrance GW. Measurements of health states utilities for economic appraisal: a review. J Health Econ. 1986;5:1–30.PubMedCrossRef
5.
Dolan P, Gudex C, Kind P, Williams A. The time trade-off method: results from a general population study. Health Econ. 1996;5(2):141–54.PubMedCrossRef
6.
Hsu PC, Krajden M, Yoshida EM, Anderson FH, Tomlinson GA, Krahn MD. Does cirrhosis affect quality of life in hepatitis C virus-infected patients? Liver Int. 2009;29(3):449–58.PubMedCrossRef
7.
Kontodimopoulos N, Niakas D. Overcoming inherent problems of preference-based techniques for measuring health benefits: an empirical study in the context of kidney transplantation. BMC Health Serv Res. 2006;6:3.PubMedPubMedCentralCrossRef
8.
Augestad LA, Rand-Hendriksen K, Stavem K, Kristiansen IS. Time trade-off and attitudes toward euthanasia: implications of using ‘death’ as an anchor in health state valuation. Qual Life Res. 2013;22(4):705–14.PubMedCrossRef
9.
Best JH, Garrison LP, Hollingworth W, Ramsey SD, Veenstra DL. Preference values associated with stage III colon cancer and adjuvant chemotherapy. Qual Life Res. 2010;19(3):391–400.PubMedCrossRef
10.
Hsu PC, Federico CA, Krajden M, Yoshida EM, Bremner KE, Anderson FH, et al. Health utilities and psychometric quality of life in patients with early- and late-stage hepatitis C virus infection. J Gastroenterol Hepatol. 2012;27(1):149–57.PubMedCrossRef
11.
Ayalon L, King-Kallimanis BL. Trading years for perfect health: results from the health and retirement study. J Aging Health. 2010;22(8):1184–97.PubMedCrossRef
12.
Shimizu F, Fujino K, Ito YM, Fukuda T, Kawachi Y, Minowada S, et al. Factors associated with variation in utility scores among patients with prostate cancer. Value Health. 2008;11(7):1190–3.PubMedCrossRef
13.
Zarate V, Kind P, Chuang LH. Hispanic valuation of the EQ-5D health states: a social value set for Latin Americans. Value Health. 2008;11(7):1170–7.PubMedCrossRef
14.
Brown MM, Brown GC, Sharma S, Landy J, Bakal J. Quality of life with visual acuity loss from diabetic retinopathy and age-related macular degeneration. Arch Ophthalmol. 2002;120(4):481–4.PubMedCrossRef
15.
Gupta V, Srinivasan G, Mei SS, Gazzard G, Sihota R, Kapoor KS. Utility values among glaucoma patients: an impact on the quality of life. Br J Ophthalmol. 2005;89(10):1241–4.PubMedPubMedCentralCrossRef
16.
Tamayama K, Kondo M, Shono A, Okubo I. Utility weights for allergic rhinitis based on a community survey with a time trade-off technique in Japan. Allergol Int. 2009;58(2):201–7.PubMedCrossRef
17.
Wells CD, Murrill WB, Arguedas MR. Comparison of health-related quality of life preferences between physicians and cirrhotic patients: implications for cost-utility analyses in chronic liver disease. Dig Dis Sci. 2004;49(3):453–8.PubMedCrossRef
18.
Rutten-van Mölken MP, Hoogendoorn M, Lamers LM. Holistic preferences for 1-year health profiles describing fluctuations in health: the case of chronic obstructive pulmonary disease. Pharmacoeconomics. 2009;27(6):465–77.PubMedCrossRef
19.
Heintz E, Krol M, Levin LÅ. The impact of patients’ subjective life expectancy on time tradeoff valuations. Med Decis Making. 2013;33(2):261–70.PubMedCrossRef
20.
van Nooten F, Brouwer W. The influence of subjective expectations about length and quality of life on time trade-off answers. Health Econ. 2004;13(8):819–23.PubMedCrossRef
21.
van Nooten FE, Koolman X, Brouwer WB. The influence of subjective life expectancy on health state valuations using a 10 year TTO. Health Econ. 2009;18(5):549–58.PubMedCrossRef
22.
van Nooten FE, Koolman X, Busschbach JJ, Brouwer WB. Thirty down, only ten to go?! Awareness and influence of a 10-year time frame in TTO. Qual Life Res. 2014;23(2):377–84.PubMedCrossRef
23.
van Nooten FE, NJA van Exel, X Koolman, WBF Brouwer. Married with children: The influence of significant others in TTO exercises. Health & Quality of Life Outcomes 2015. Health Qual Life Outcomes. 2015;13:94.
24.
25.
van Osch S.M.C., Stiggelbout A.M. The development of the Health-Risk Attitude Scale. In: Van Osch, S. M. C.. The Construction of Health State Utilities, 117–138. 2007. Leiden: Department Medical Decision Making, Medicine / Leiden University Medical Center (LUMC),Leiden University. Last accessed Oct 20, 2014, on http://​openaccess.​leidenuniv.​nl/​.
26.
Sarkisian CA, Steers WN, Hays RD, Mangione CM. Development of the 12-item Expectations Regarding Aging Survey. Gerontologist. 2005;45(2):240–8.PubMedCrossRef
27.
Attema AE, Versteegh MM, Oppe M, Brouwer WB, Stolk EA. Lead time TTO: leading to better health state valuations? Health Econ. 2013;22(4):376–92.PubMedCrossRef
28.
Attema AE, Brouwer WBF. In search of a preferred preference elicitation method. A test of the internal consistency of choice and matching tasks. J Econ Psych. 2013;39:126–40.CrossRef
Metadata
Title
“Back to the future”: Influence of beliefs regarding the future on TTO answers
Authors
F. E. van Nooten
N.J.A. van Exel
D. Eriksson
W.B.F. Brouwer
Publication date
01-12-2016
Publisher
BioMed Central
Published in
Health and Quality of Life Outcomes / Issue 1/2016
Electronic ISSN: 1477-7525
DOI
https://doi.org/10.1186/s12955-015-0402-6

Other articles of this Issue 1/2016

Health and Quality of Life Outcomes 1/2016 Go to the issue

Research

From early detection to rehabilitation in the community: reading beyond the blog testimonies of survivors’ quality of life and prostate cancer representation

Research

Well-being and associated factors among adults in the occupied Palestinian territory (oPt)

Research

Assessing quality of life in a clinical study on heart rehabilitation patients: how well do value sets based on given or experienced health states reflect patients’ valuations?

Research

Vision-related quality of life in patients receiving intravitreal ranibizumab injections in routine clinical practice: baseline data from the German OCEAN study

Research

Impact of the occurrence of a response shift on the determination of the minimal important difference in a health-related quality of life score over time

Research

Estimation of minimal clinically important change of the Japanese version of EQ-5D in patients with chronic noncancer pain: a retrospective research using real-world data