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Published in: Hepatology International 2/2021

Open Access 01-04-2021 | Azathioprine | Guidelines

The Asian Pacific Association for the Study of the Liver clinical practice guidance: the diagnosis and management of patients with autoimmune hepatitis

Authors: Guiqiang Wang, Atsushi Tanaka, Hong Zhao, Jidong Jia, Xiong Ma, Kenichi Harada, Fu-Sheng Wang, Lai Wei, Qixia Wang, Ying Sun, Yuan Hong, Huiying Rao, Cumali Efe, George Lau, Diana Payawal, Rino Gani, Keith Lindor, Wasim Jafri, Masao Omata, Shiv Kumar Sarin

Published in: Hepatology International | Issue 2/2021

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Excerpt

Autoimmune hepatitis (AIH) is not a common disease but with increasing incidence in Asia–Pacific area. Although the etiology and pathogenesis are not completely clear, the disease is the result of loss of autoimmune tolerance in genetically predisposed individuals. AIH is characterized by autoantibodies, hypergammaglobulinemia, and interface hepatitis. Corticosteroids and azathioprine are standard regimens for AIH, which should be started after diagnosis. Alternative therapy should be considered for those who do not respond to standard regimens. End-stage AIH patient could be saved by liver transplantation. …
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Metadata
Title
The Asian Pacific Association for the Study of the Liver clinical practice guidance: the diagnosis and management of patients with autoimmune hepatitis
Authors
Guiqiang Wang
Atsushi Tanaka
Hong Zhao
Jidong Jia
Xiong Ma
Kenichi Harada
Fu-Sheng Wang
Lai Wei
Qixia Wang
Ying Sun
Yuan Hong
Huiying Rao
Cumali Efe
George Lau
Diana Payawal
Rino Gani
Keith Lindor
Wasim Jafri
Masao Omata
Shiv Kumar Sarin
Publication date
01-04-2021
Publisher
Springer India
Published in
Hepatology International / Issue 2/2021
Print ISSN: 1936-0533
Electronic ISSN: 1936-0541
DOI
https://doi.org/10.1007/s12072-021-10170-1

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