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Open Access 01-02-2020 | Autopsy | Review and Perspectives

Diagnosis of myocardial infarction at autopsy: AECVP reappraisal in the light of the current clinical classification

Authors: Katarzyna Michaud, Cristina Basso, Giulia d’Amati, Carla Giordano, Ivana Kholová, Stephen D. Preston, Stefania Rizzo, Sara Sabatasso, Mary N. Sheppard, Aryan Vink, Allard C. van der Wal, on behalf of the Association for European Cardiovascular Pathology (AECVP)

Published in: Virchows Archiv | Issue 2/2020

Abstract

Ischemic heart disease is one of the leading causes of morbidity and death worldwide. Consequently, myocardial infarctions are often encountered in clinical and forensic autopsies, and diagnosis can be challenging, especially in the absence of an acute coronary occlusion. Precise histopathological identification and timing of myocardial infarction in humans often remains uncertain while it can be of crucial importance, especially in a forensic setting when third person involvement or medical responsibilities are in question. A proper post-mortem diagnosis requires not only up-to-date knowledge of the ischemic coronary and myocardial pathology, but also a correct interpretation of such findings in relation to the clinical scenario of the deceased. For these reasons, it is important for pathologists to be familiar with the different clinically defined types of myocardial infarction and to discriminate myocardial infarction from other forms of myocardial injury. This article reviews present knowledge and post-mortem diagnostic methods, including post-mortem imaging, to reveal the different types of myocardial injury and the clinical-pathological correlations with currently defined types of myocardial infarction.

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Title: Diagnosis of myocardial infarction at autopsy: AECVP reappraisal in the light of the current clinical classification
Authors: Katarzyna Michaud
Cristina Basso
Giulia d’Amati
Carla Giordano
Ivana Kholová
Stephen D. Preston
Stefania Rizzo
Sara Sabatasso
Mary N. Sheppard
Aryan Vink
Allard C. van der Wal
on behalf of the Association for European Cardiovascular Pathology (AECVP)
Publication date: 01-02-2020
Publisher: Springer Berlin Heidelberg
Keywords: Autopsy
Myocardial Infarction
Acute Coronary Syndrome
Published in: Virchows Archiv / Issue 2/2020
Print ISSN: 0945-6317
Electronic ISSN: 1432-2307
DOI: https://doi.org/10.1007/s00428-019-02662-1

At a glance: The STEP trials

Springer Medicine

Diagnosis of myocardial infarction at autopsy: AECVP reappraisal in the light of the current clinical classification

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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Comparison of PD-L1 expression between paired cytologic and histologic specimens from non-small cell lung cancer patients

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Non-conventional mucosal lesions (serrated epithelial change, villous hypermucinous change) are frequent in patients with inflammatory bowel disease—results of molecular and immunohistochemical single institutional study

Correction to: Abstracts

Mutational Screening of BRCA1/2 Genes as a Predictive Factor for Therapeutic Response in Epithelial Ovarian Cancer: A Consensus Guide from the Spanish Society of Pathology (SEAP-IAP) and the Spanish Society of Human Genetics (AEGH)