Skip to main content
Top
Published in: Virchows Archiv 5/2019

Open Access 01-11-2019 | Autopsy | Original Article

Performance of the minimally invasive autopsy tool for cause of death determination in adult deaths from the Brazilian Amazon: an observational study

Authors: Antonio E. M. Palhares, Luiz Ferreira, Monique Freire, Paola Castillo, Miguel J Martínez, Juan Carlos Hurtado, Natalia Rakislova, Rosauro Varo, Mireia Navarro, Isaac Casas, Jordi Vila, Wuelton M. Monteiro, Ariadna Sanz, Llorenç Quintó, Fabiola Fernandes, Carla Carrilho, Clara Menéndez, Jaume Ordi, Quique Bassat, Marcus Lacerda

Published in: Virchows Archiv | Issue 5/2019

Login to get access

Abstract

The uncertainty about the real burden of causes of death (CoD) is increasingly recognized by the international health community as a critical limitation for prioritizing effective public health measures. The minimally invasive autopsy (MIA) has shown to be a satisfactory substitute of the complete diagnostic autopsy (CDA), the gold standard for CoD determination in low- and middle-income countries. However, more studies are needed to confirm its adequate performance in settings with different epidemiology. In this observational study, the CoD obtained with the MIA were compared with the clinical diagnosis and the results of the CDA in 61 deaths that occurred in an infectious diseases referral hospital in Manaus, Brazilian Amazon. Concordance between the categories of diseases obtained by the three methods was evaluated by the Kappa statistic. Additionally, we evaluated discrepancies between clinical and complete diagnostic autopsy diagnoses. The MIA showed a substantial concordance with the CDA (Kappa = 0.777, 95% CI 0.608–0.946), and a perfect or almost perfect coincidence in specific diagnosis (ICD-10 code) between MIA and CDA was observed in 85% of the cases. In contrast, the clinical diagnosis showed a fair concordance with the CDA (Kappa = 0.311, 95% CI 0.071–0.552). Major clinico-pathological discrepancies were identified in 49% of cases. In conclusion, the MIA showed a substantial performance for CoD identification. Clinico-pathological discrepancies remain high and justify the need for post-mortem studies, even in referral hospitals. The MIA is a robust substitute of the CDA for CoD surveillance and quality improvement of clinical practice in low- and middle-income settings.
Appendix
Available only for authorised users
Literature
1.
go back to reference Wang H, Abajobir AA, Abate KH, Abbafati C, Abbas KM, Abd-Allah F, Abera SF, Abraha HN, Abu-Raddad LJ, Abu-Rmeileh NME, Adedeji IA, Adedoyin RA, Adetifa IMO, Adetokunboh O, Afshin A, Aggarwal R, Agrawal A, Agrawal S, Ahmad Kiadaliri A, Ahmed MB, Aichour MTE, Aichour AN, Aichour I, Aiyar S, Akanda AS, Akinyemiju TF, Akseer N, al Lami FH, Alabed S, Alahdab F, al-Aly Z, Alam K, Alam N, Alasfoor D, Aldridge RW, Alene KA, al-Eyadhy A, Alhabib S, Ali R, Alizadeh-Navaei R, Aljunid SM, Alkaabi JM, Alkerwi A’, Alla F, Allam SD, Allebeck P, al-Raddadi R, Alsharif U, Altirkawi KA, Alvis-Guzman N, Amare AT, Ameh EA, Amini E, Ammar W, Amoako YA, Anber N, Andrei CL, Androudi S, Ansari H, Ansha MG, Antonio CAT, Anwari P, Ärnlöv J, Arora M, Artaman A, Aryal KK, Asayesh H, Asgedom SW, Asghar RJ, Assadi R, Assaye AM, Atey TM, Atre SR, Avila-Burgos L, Avokpaho EFGA, Awasthi A, Babalola TK, Bacha U, Badawi A, Balakrishnan K, Balalla S, Barac A, Barber RM, Barboza MA, Barker-Collo SL, Bärnighausen T, Barquera S, Barregard L, Barrero LH, Baune BT, Bazargan-Hejazi S, Bedi N, Beghi E, Béjot Y, Bekele BB, Bell ML, Bello AK, Bennett DA, Bennett JR, Bensenor IM, Benson J, Berhane A, Berhe DF, Bernabé E, Beuran M, Beyene AS, Bhala N, Bhansali A, Bhaumik S, Bhutta ZA, Bicer BK, Bidgoli HH, Bikbov B, Birungi C, Biryukov S, Bisanzio D, Bizuayehu HM, Bjerregaard P, Blosser CD, Boneya DJ, Boufous S, Bourne RRA, Brazinova A, Breitborde NJK, Brenner H, Brugha TS, Bukhman G, Bulto LNB, Bumgarner BR, Burch M, Butt ZA, Cahill LE, Cahuana-Hurtado L, Campos-Nonato IR, Car J, Car M, Cárdenas R, Carpenter DO, Carrero JJ, Carter A, Castañeda-Orjuela CA, Castro FF, Castro RE, Catalá-López F, Chen H, Chiang PPC, Chibalabala M, Chisumpa VH, Chitheer AA, Choi JYJ, Christensen H, Christopher DJ, Ciobanu LG, Cirillo M, Cohen AJ, Colquhoun SM, Coresh J, Criqui MH, Cromwell EA, Crump JA, Dandona L, Dandona R, Dargan PI, das Neves J, Davey G, Davitoiu DV, Davletov K, de Courten B, de Leo D, Degenhardt L, Deiparine S, Dellavalle RP, Deribe K, Deribew A, Des Jarlais DC, Dey S, Dharmaratne SD, Dherani MK, Diaz-Torné C, Ding EL, Dixit P, Djalalinia S, Do HP, Doku DT, Donnelly CA, dos Santos KPB, Douwes-Schultz D, Driscoll TR, Duan L, Dubey M, Duncan BB, Dwivedi LK, Ebrahimi H, el Bcheraoui C, Ellingsen CL, Enayati A, Endries AY, Ermakov SP, Eshetie S, Eshrati B, Eskandarieh S, Esteghamati A, Estep K, Fanuel FBB, Faro A, Farvid MS, Farzadfar F, Feigin VL, Fereshtehnejad SM, Fernandes JG, Fernandes JC, Feyissa TR, Filip I, Fischer F, Foigt N, Foreman KJ, Frank T, Franklin RC, Fraser M, Friedman J, Frostad JJ, Fullman N, Fürst T, Furtado JM, Futran ND, Gakidou E, Gambashidze K, Gamkrelidze A, Gankpé FG, Garcia-Basteiro AL, Gebregergs GB, Gebrehiwot TT, Gebrekidan KG, Gebremichael MW, Gelaye AA, Geleijnse JM, Gemechu BL, Gemechu KS, Genova-Maleras R, Gesesew HA, Gething PW, Gibney KB, Gill PS, Gillum RF, Giref AZ, Girma BW, Giussani G, Goenka S, Gomez B, Gona PN, Gopalani SV, Goulart AC, Graetz N, Gugnani HC, Gupta PC, Gupta R, Gupta R, Gupta T, Gupta V, Haagsma JA, Hafezi-Nejad N, Hakuzimana A, Halasa YA, Hamadeh RR, Hambisa MT, Hamidi S, Hammami M, Hancock J, Handal AJ, Hankey GJ, Hao Y, Harb HL, Hareri HA, Harikrishnan S, Haro JM, Hassanvand MS, Havmoeller R, Hay RJ, Hay SI, He F, Heredia-Pi IB, Herteliu C, Hilawe EH, Hoek HW, Horita N, Hosgood HD, Hostiuc S, Hotez PJ, Hoy DG, Hsairi M, Htet AS, Hu G, Huang JJ, Huang H, Iburg KM, Igumbor EU, Ileanu BV, Inoue M, Irenso AA, Irvine CMS, Islam SMS, Islam N, Jacobsen KH, Jaenisch T, Jahanmehr N, Jakovljevic MB, Javanbakht M, Jayatilleke AU, Jeemon P, Jensen PN, Jha V, Jin Y, John D, John O, Johnson SC, Jonas JB, Jürisson M, Kabir Z, Kadel R, Kahsay A, Kalkonde Y, Kamal R, Kan H, Karch A, Karema CK, Karimi SM, Karthikeyan G, Kasaeian A, Kassaw NA, Kassebaum NJ, Kastor A, Katikireddi SV, Kaul A, Kawakami N, Kazanjan K, Keiyoro PN, Kelbore SG, Kemp AH, Kengne AP, Keren A, Kereselidze M, Kesavachandran CN, Ketema EB, Khader YS, Khalil IA, Khan EA, Khan G, Khang YH, Khera S, Khoja ATA, Khosravi MH, Kibret GD, Kieling C, Kim YJ, Kim CI, Kim D, Kim P, Kim S, Kimokoti RW, Kinfu Y, Kishawi S, Kissoon N, Kivimaki M, Knudsen AK, Kokubo Y, Kopec JA, Kosen S, Koul PA, Koyanagi A, Kravchenko M, Krohn KJ, Kuate Defo B, Kuipers EJ, Kulikoff XR, Kulkarni VS, Kumar GA, Kumar P, Kumsa FA, Kutz M, Lachat C, Lagat AK, Lager ACJ, Lal DK, Lalloo R, Lambert N, Lan Q, Lansingh VC, Larson HJ, Larsson A, Laryea DO, Lavados PM, Laxmaiah A, Lee PH, Leigh J, Leung J, Leung R, Levi M, Li Y, Liao Y, Liben ML, Lim SS, Linn S, Lipshultz SE, Liu S, Lodha R, Logroscino G, Lorch SA, Lorkowski S, Lotufo PA, Lozano R, Lunevicius R, Lyons RA, Ma S, Macarayan ERK, Machado IE, Mackay MT, Magdy Abd el Razek M, Magis-Rodriguez C, Mahdavi M, Majdan M, Majdzadeh R, Majeed A, Malekzadeh R, Malhotra R, Malta DC, Mantovani LG, Manyazewal T, Mapoma CC, Marczak LB, Marks GB, Martin EA, Martinez-Raga J, Martins-Melo FR, Massano J, Maulik PK, Mayosi BM, Mazidi M, McAlinden C, McGarvey ST, McGrath JJ, McKee M, Mehata S, Mehndiratta MM, Mehta KM, Meier T, Mekonnen TC, Meles KG, Memiah P, Memish ZA, Mendoza W, Mengesha MM, Mengistie MA, Mengistu DT, Menon GR, Menota BG, Mensah GA, Meretoja TJ, Meretoja A, Mezgebe HB, Micha R, Mikesell J, Miller TR, Mills EJ, Minnig S, Mirarefin M, Mirrakhimov EM, Misganaw A, Mishra SR, Mohammad KA, Mohammadi A, Mohammed KE, Mohammed S, Mohan MBV, Mohanty SK, Mokdad AH, Mollenkopf SK, Molokhia M, Monasta L, Montañez Hernandez JC, Montico M, Mooney MD, Moore AR, Moradi-Lakeh M, Moraga P, Morawska L, Mori R, Morrison SD, Mruts KB, Mueller UO, Mullany E, Muller K, Murthy GVS, Murthy S, Musa KI, Nachega JB, Nagata C, Nagel G, Naghavi M, Naidoo KS, Nanda L, Nangia V, Nascimento BR, Natarajan G, Negoi I, Nguyen CT, Nguyen QL, Nguyen TH, Nguyen G, Ningrum DNA, Nisar MI, Nomura M, Nong VM, Norheim OF, Norrving B, Noubiap JJN, Nyakarahuka L, O’Donnell MJ, Obermeyer CM, Ogbo FA, Oh IH, Okoro A, Oladimeji O, Olagunju AT, Olusanya BO, Olusanya JO, Oren E, Ortiz A, Osgood-Zimmerman A, Ota E, Owolabi MO, Oyekale AS, PA M, Pacella RE, Pakhale S, Pana A, Panda BK, Panda-Jonas S, Park EK, Parsaeian M, Patel T, Patten SB, Patton GC, Paudel D, Pereira DM, Perez-Padilla R, Perez-Ruiz F, Perico N, Pervaiz A, Pesudovs K, Peterson CB, Petri WA, Petzold M, Phillips MR, Piel FB, Pigott DM, Pishgar F, Plass D, Polinder S, Popova S, Postma MJ, Poulton RG, Pourmalek F, Prasad N, Purwar M, Qorbani M, Quintanilla BPA, Rabiee RHS, Radfar A, Rafay A, Rahimi-Movaghar A, Rahimi-Movaghar V, Rahman MHU, Rahman SU, Rahman M, Rai RK, Rajsic S, Ram U, Rana SM, Ranabhat CL, Rao PV, Rawaf S, Ray SE, Rego MAS, Rehm J, Reiner RC, Remuzzi G, Renzaho AMN, Resnikoff S, Rezaei S, Rezai MS, Ribeiro AL, Rivas JC, Rokni MB, Ronfani L, Roshandel G, Roth GA, Rothenbacher D, Roy A, Rubagotti E, Ruhago GM, Saadat S, Sabde YD, Sachdev PS, Sadat N, Safdarian M, Safi S, Safiri S, Sagar R, Sahathevan R, Sahebkar A, Sahraian MA, Salama J, Salamati P, Salomon JA, Salvi SS, Samy AM, Sanabria JR, Sanchez-Niño MD, Santos IS, Santric Milicevic MM, Sarmiento-Suarez R, Sartorius B, Satpathy M, Sawhney M, Saxena S, Saylan MI, Schmidt MI, Schneider IJC, Schulhofer-Wohl S, Schutte AE, Schwebel DC, Schwendicke F, Seedat S, Seid AM, Sepanlou SG, Servan-Mori EE, Shackelford KA, Shaheen A, Shahraz S, Shaikh MA, Shamsipour M, Shamsizadeh M, Sharma J, Sharma R, She J, Shen J, Shetty BP, Shi P, Shibuya K, Shifa GT, Shigematsu M, Shiri R, Shiue I, Shrime MG, Sigfusdottir ID, Silberberg DH, Silpakit N, Silva DAS, Silva JP, Silveira DGA, Sindi S, Singh JA, Singh PK, Singh A, Singh V, Sinha DN, Skarbek KAK, Skiadaresi E, Sligar A, Smith DL, Sobaih BHA, Sobngwi E, Soneji S, Soriano JB, Sreeramareddy CT, Srinivasan V, Stathopoulou V, Steel N, Stein DJ, Steiner C, Stöckl H, Stokes MA, Strong M, Sufiyan MB, Suliankatchi RA, Sunguya BF, Sur PJ, Swaminathan S, Sykes BL, Szoeke CEI, Tabarés-Seisdedos R, Tadakamadla SK, Tadese F, Tandon N, Tanne D, Tarajia M, Tavakkoli M, Taveira N, Tehrani-Banihashemi A, Tekelab T, Tekle DY, Temsah MH, Terkawi AS, Tesema CL, Tesssema B, Theis A, Thomas N, Thompson AH, Thomson AJ, Thrift AG, Tiruye TY, Tobe-Gai R, Tonelli M, Topor-Madry R, Topouzis F, Tortajada M, Tran BX, Truelsen T, Trujillo U, Tsilimparis N, Tuem KB, Tuzcu EM, Tyrovolas S, Ukwaja KN, Undurraga EA, Uthman OA, Uzochukwu BSC, van Boven JFM, Varakin YY, Varughese S, Vasankari T, Vasconcelos AMN, Velasquez IM, Venketasubramanian N, Vidavalur R, Violante FS, Vishnu A, Vladimirov SK, Vlassov VV, Vollset SE, Vos T, Waid JL, Wakayo T, Wang YP, Weichenthal S, Weiderpass E, Weintraub RG, Werdecker A, Wesana J, Wijeratne T, Wilkinson JD, Wiysonge CS, Woldeyes BG, Wolfe CDA, Workicho A, Workie SB, Xavier D, Xu G, Yaghoubi M, Yakob B, Yalew AZ, Yan LL, Yano Y, Yaseri M, Ye P, Yimam HH, Yip P, Yirsaw BD, Yonemoto N, Yoon SJ, Yotebieng M, Younis MZ, Zaidi Z, Zaki MES, Zeeb H, Zenebe ZM, Zerfu TA, Zhang AL, Zhang X, Zodpey S, Zuhlke LJ, Lopez AD, Murray CJL (2017) Global, regional, and national under-5 mortality, adult mortality, age-specific mortality, and life expectancy, 1970–2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet 390:1084–1150CrossRef Wang H, Abajobir AA, Abate KH, Abbafati C, Abbas KM, Abd-Allah F, Abera SF, Abraha HN, Abu-Raddad LJ, Abu-Rmeileh NME, Adedeji IA, Adedoyin RA, Adetifa IMO, Adetokunboh O, Afshin A, Aggarwal R, Agrawal A, Agrawal S, Ahmad Kiadaliri A, Ahmed MB, Aichour MTE, Aichour AN, Aichour I, Aiyar S, Akanda AS, Akinyemiju TF, Akseer N, al Lami FH, Alabed S, Alahdab F, al-Aly Z, Alam K, Alam N, Alasfoor D, Aldridge RW, Alene KA, al-Eyadhy A, Alhabib S, Ali R, Alizadeh-Navaei R, Aljunid SM, Alkaabi JM, Alkerwi A’, Alla F, Allam SD, Allebeck P, al-Raddadi R, Alsharif U, Altirkawi KA, Alvis-Guzman N, Amare AT, Ameh EA, Amini E, Ammar W, Amoako YA, Anber N, Andrei CL, Androudi S, Ansari H, Ansha MG, Antonio CAT, Anwari P, Ärnlöv J, Arora M, Artaman A, Aryal KK, Asayesh H, Asgedom SW, Asghar RJ, Assadi R, Assaye AM, Atey TM, Atre SR, Avila-Burgos L, Avokpaho EFGA, Awasthi A, Babalola TK, Bacha U, Badawi A, Balakrishnan K, Balalla S, Barac A, Barber RM, Barboza MA, Barker-Collo SL, Bärnighausen T, Barquera S, Barregard L, Barrero LH, Baune BT, Bazargan-Hejazi S, Bedi N, Beghi E, Béjot Y, Bekele BB, Bell ML, Bello AK, Bennett DA, Bennett JR, Bensenor IM, Benson J, Berhane A, Berhe DF, Bernabé E, Beuran M, Beyene AS, Bhala N, Bhansali A, Bhaumik S, Bhutta ZA, Bicer BK, Bidgoli HH, Bikbov B, Birungi C, Biryukov S, Bisanzio D, Bizuayehu HM, Bjerregaard P, Blosser CD, Boneya DJ, Boufous S, Bourne RRA, Brazinova A, Breitborde NJK, Brenner H, Brugha TS, Bukhman G, Bulto LNB, Bumgarner BR, Burch M, Butt ZA, Cahill LE, Cahuana-Hurtado L, Campos-Nonato IR, Car J, Car M, Cárdenas R, Carpenter DO, Carrero JJ, Carter A, Castañeda-Orjuela CA, Castro FF, Castro RE, Catalá-López F, Chen H, Chiang PPC, Chibalabala M, Chisumpa VH, Chitheer AA, Choi JYJ, Christensen H, Christopher DJ, Ciobanu LG, Cirillo M, Cohen AJ, Colquhoun SM, Coresh J, Criqui MH, Cromwell EA, Crump JA, Dandona L, Dandona R, Dargan PI, das Neves J, Davey G, Davitoiu DV, Davletov K, de Courten B, de Leo D, Degenhardt L, Deiparine S, Dellavalle RP, Deribe K, Deribew A, Des Jarlais DC, Dey S, Dharmaratne SD, Dherani MK, Diaz-Torné C, Ding EL, Dixit P, Djalalinia S, Do HP, Doku DT, Donnelly CA, dos Santos KPB, Douwes-Schultz D, Driscoll TR, Duan L, Dubey M, Duncan BB, Dwivedi LK, Ebrahimi H, el Bcheraoui C, Ellingsen CL, Enayati A, Endries AY, Ermakov SP, Eshetie S, Eshrati B, Eskandarieh S, Esteghamati A, Estep K, Fanuel FBB, Faro A, Farvid MS, Farzadfar F, Feigin VL, Fereshtehnejad SM, Fernandes JG, Fernandes JC, Feyissa TR, Filip I, Fischer F, Foigt N, Foreman KJ, Frank T, Franklin RC, Fraser M, Friedman J, Frostad JJ, Fullman N, Fürst T, Furtado JM, Futran ND, Gakidou E, Gambashidze K, Gamkrelidze A, Gankpé FG, Garcia-Basteiro AL, Gebregergs GB, Gebrehiwot TT, Gebrekidan KG, Gebremichael MW, Gelaye AA, Geleijnse JM, Gemechu BL, Gemechu KS, Genova-Maleras R, Gesesew HA, Gething PW, Gibney KB, Gill PS, Gillum RF, Giref AZ, Girma BW, Giussani G, Goenka S, Gomez B, Gona PN, Gopalani SV, Goulart AC, Graetz N, Gugnani HC, Gupta PC, Gupta R, Gupta R, Gupta T, Gupta V, Haagsma JA, Hafezi-Nejad N, Hakuzimana A, Halasa YA, Hamadeh RR, Hambisa MT, Hamidi S, Hammami M, Hancock J, Handal AJ, Hankey GJ, Hao Y, Harb HL, Hareri HA, Harikrishnan S, Haro JM, Hassanvand MS, Havmoeller R, Hay RJ, Hay SI, He F, Heredia-Pi IB, Herteliu C, Hilawe EH, Hoek HW, Horita N, Hosgood HD, Hostiuc S, Hotez PJ, Hoy DG, Hsairi M, Htet AS, Hu G, Huang JJ, Huang H, Iburg KM, Igumbor EU, Ileanu BV, Inoue M, Irenso AA, Irvine CMS, Islam SMS, Islam N, Jacobsen KH, Jaenisch T, Jahanmehr N, Jakovljevic MB, Javanbakht M, Jayatilleke AU, Jeemon P, Jensen PN, Jha V, Jin Y, John D, John O, Johnson SC, Jonas JB, Jürisson M, Kabir Z, Kadel R, Kahsay A, Kalkonde Y, Kamal R, Kan H, Karch A, Karema CK, Karimi SM, Karthikeyan G, Kasaeian A, Kassaw NA, Kassebaum NJ, Kastor A, Katikireddi SV, Kaul A, Kawakami N, Kazanjan K, Keiyoro PN, Kelbore SG, Kemp AH, Kengne AP, Keren A, Kereselidze M, Kesavachandran CN, Ketema EB, Khader YS, Khalil IA, Khan EA, Khan G, Khang YH, Khera S, Khoja ATA, Khosravi MH, Kibret GD, Kieling C, Kim YJ, Kim CI, Kim D, Kim P, Kim S, Kimokoti RW, Kinfu Y, Kishawi S, Kissoon N, Kivimaki M, Knudsen AK, Kokubo Y, Kopec JA, Kosen S, Koul PA, Koyanagi A, Kravchenko M, Krohn KJ, Kuate Defo B, Kuipers EJ, Kulikoff XR, Kulkarni VS, Kumar GA, Kumar P, Kumsa FA, Kutz M, Lachat C, Lagat AK, Lager ACJ, Lal DK, Lalloo R, Lambert N, Lan Q, Lansingh VC, Larson HJ, Larsson A, Laryea DO, Lavados PM, Laxmaiah A, Lee PH, Leigh J, Leung J, Leung R, Levi M, Li Y, Liao Y, Liben ML, Lim SS, Linn S, Lipshultz SE, Liu S, Lodha R, Logroscino G, Lorch SA, Lorkowski S, Lotufo PA, Lozano R, Lunevicius R, Lyons RA, Ma S, Macarayan ERK, Machado IE, Mackay MT, Magdy Abd el Razek M, Magis-Rodriguez C, Mahdavi M, Majdan M, Majdzadeh R, Majeed A, Malekzadeh R, Malhotra R, Malta DC, Mantovani LG, Manyazewal T, Mapoma CC, Marczak LB, Marks GB, Martin EA, Martinez-Raga J, Martins-Melo FR, Massano J, Maulik PK, Mayosi BM, Mazidi M, McAlinden C, McGarvey ST, McGrath JJ, McKee M, Mehata S, Mehndiratta MM, Mehta KM, Meier T, Mekonnen TC, Meles KG, Memiah P, Memish ZA, Mendoza W, Mengesha MM, Mengistie MA, Mengistu DT, Menon GR, Menota BG, Mensah GA, Meretoja TJ, Meretoja A, Mezgebe HB, Micha R, Mikesell J, Miller TR, Mills EJ, Minnig S, Mirarefin M, Mirrakhimov EM, Misganaw A, Mishra SR, Mohammad KA, Mohammadi A, Mohammed KE, Mohammed S, Mohan MBV, Mohanty SK, Mokdad AH, Mollenkopf SK, Molokhia M, Monasta L, Montañez Hernandez JC, Montico M, Mooney MD, Moore AR, Moradi-Lakeh M, Moraga P, Morawska L, Mori R, Morrison SD, Mruts KB, Mueller UO, Mullany E, Muller K, Murthy GVS, Murthy S, Musa KI, Nachega JB, Nagata C, Nagel G, Naghavi M, Naidoo KS, Nanda L, Nangia V, Nascimento BR, Natarajan G, Negoi I, Nguyen CT, Nguyen QL, Nguyen TH, Nguyen G, Ningrum DNA, Nisar MI, Nomura M, Nong VM, Norheim OF, Norrving B, Noubiap JJN, Nyakarahuka L, O’Donnell MJ, Obermeyer CM, Ogbo FA, Oh IH, Okoro A, Oladimeji O, Olagunju AT, Olusanya BO, Olusanya JO, Oren E, Ortiz A, Osgood-Zimmerman A, Ota E, Owolabi MO, Oyekale AS, PA M, Pacella RE, Pakhale S, Pana A, Panda BK, Panda-Jonas S, Park EK, Parsaeian M, Patel T, Patten SB, Patton GC, Paudel D, Pereira DM, Perez-Padilla R, Perez-Ruiz F, Perico N, Pervaiz A, Pesudovs K, Peterson CB, Petri WA, Petzold M, Phillips MR, Piel FB, Pigott DM, Pishgar F, Plass D, Polinder S, Popova S, Postma MJ, Poulton RG, Pourmalek F, Prasad N, Purwar M, Qorbani M, Quintanilla BPA, Rabiee RHS, Radfar A, Rafay A, Rahimi-Movaghar A, Rahimi-Movaghar V, Rahman MHU, Rahman SU, Rahman M, Rai RK, Rajsic S, Ram U, Rana SM, Ranabhat CL, Rao PV, Rawaf S, Ray SE, Rego MAS, Rehm J, Reiner RC, Remuzzi G, Renzaho AMN, Resnikoff S, Rezaei S, Rezai MS, Ribeiro AL, Rivas JC, Rokni MB, Ronfani L, Roshandel G, Roth GA, Rothenbacher D, Roy A, Rubagotti E, Ruhago GM, Saadat S, Sabde YD, Sachdev PS, Sadat N, Safdarian M, Safi S, Safiri S, Sagar R, Sahathevan R, Sahebkar A, Sahraian MA, Salama J, Salamati P, Salomon JA, Salvi SS, Samy AM, Sanabria JR, Sanchez-Niño MD, Santos IS, Santric Milicevic MM, Sarmiento-Suarez R, Sartorius B, Satpathy M, Sawhney M, Saxena S, Saylan MI, Schmidt MI, Schneider IJC, Schulhofer-Wohl S, Schutte AE, Schwebel DC, Schwendicke F, Seedat S, Seid AM, Sepanlou SG, Servan-Mori EE, Shackelford KA, Shaheen A, Shahraz S, Shaikh MA, Shamsipour M, Shamsizadeh M, Sharma J, Sharma R, She J, Shen J, Shetty BP, Shi P, Shibuya K, Shifa GT, Shigematsu M, Shiri R, Shiue I, Shrime MG, Sigfusdottir ID, Silberberg DH, Silpakit N, Silva DAS, Silva JP, Silveira DGA, Sindi S, Singh JA, Singh PK, Singh A, Singh V, Sinha DN, Skarbek KAK, Skiadaresi E, Sligar A, Smith DL, Sobaih BHA, Sobngwi E, Soneji S, Soriano JB, Sreeramareddy CT, Srinivasan V, Stathopoulou V, Steel N, Stein DJ, Steiner C, Stöckl H, Stokes MA, Strong M, Sufiyan MB, Suliankatchi RA, Sunguya BF, Sur PJ, Swaminathan S, Sykes BL, Szoeke CEI, Tabarés-Seisdedos R, Tadakamadla SK, Tadese F, Tandon N, Tanne D, Tarajia M, Tavakkoli M, Taveira N, Tehrani-Banihashemi A, Tekelab T, Tekle DY, Temsah MH, Terkawi AS, Tesema CL, Tesssema B, Theis A, Thomas N, Thompson AH, Thomson AJ, Thrift AG, Tiruye TY, Tobe-Gai R, Tonelli M, Topor-Madry R, Topouzis F, Tortajada M, Tran BX, Truelsen T, Trujillo U, Tsilimparis N, Tuem KB, Tuzcu EM, Tyrovolas S, Ukwaja KN, Undurraga EA, Uthman OA, Uzochukwu BSC, van Boven JFM, Varakin YY, Varughese S, Vasankari T, Vasconcelos AMN, Velasquez IM, Venketasubramanian N, Vidavalur R, Violante FS, Vishnu A, Vladimirov SK, Vlassov VV, Vollset SE, Vos T, Waid JL, Wakayo T, Wang YP, Weichenthal S, Weiderpass E, Weintraub RG, Werdecker A, Wesana J, Wijeratne T, Wilkinson JD, Wiysonge CS, Woldeyes BG, Wolfe CDA, Workicho A, Workie SB, Xavier D, Xu G, Yaghoubi M, Yakob B, Yalew AZ, Yan LL, Yano Y, Yaseri M, Ye P, Yimam HH, Yip P, Yirsaw BD, Yonemoto N, Yoon SJ, Yotebieng M, Younis MZ, Zaidi Z, Zaki MES, Zeeb H, Zenebe ZM, Zerfu TA, Zhang AL, Zhang X, Zodpey S, Zuhlke LJ, Lopez AD, Murray CJL (2017) Global, regional, and national under-5 mortality, adult mortality, age-specific mortality, and life expectancy, 1970–2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet 390:1084–1150CrossRef
2.
go back to reference Blokker BM, Weustink AC, Hunink MGM, Oosterhuis JW (2017) Autopsy rates in the Netherlands: 35 years of decline. PLoS One 12:e0178200CrossRef Blokker BM, Weustink AC, Hunink MGM, Oosterhuis JW (2017) Autopsy rates in the Netherlands: 35 years of decline. PLoS One 12:e0178200CrossRef
3.
go back to reference Shojania KG, Burton EC, McDonald KM et al (2003) Changes in rates of autopsy-detected diagnostic errors over time: a systematic review. JAMA 289:2849–2856CrossRef Shojania KG, Burton EC, McDonald KM et al (2003) Changes in rates of autopsy-detected diagnostic errors over time: a systematic review. JAMA 289:2849–2856CrossRef
4.
go back to reference Burton JL, Underwood J (2007) Clinical, educational, and epidemiological value of autopsy. Lancet 369:1471–1480CrossRef Burton JL, Underwood J (2007) Clinical, educational, and epidemiological value of autopsy. Lancet 369:1471–1480CrossRef
5.
go back to reference Turnbull A, Osborn M, Nicholas N (2015) Hospital autopsy: endangered or extinct? J Clin Pathol 68:601–604CrossRef Turnbull A, Osborn M, Nicholas N (2015) Hospital autopsy: endangered or extinct? J Clin Pathol 68:601–604CrossRef
6.
go back to reference Loughrey MB, McCluggage WG, Toner PG (2000) The declining autopsy rate and clinicians’ attitudes. Ulster Med J 69:83–89PubMedPubMedCentral Loughrey MB, McCluggage WG, Toner PG (2000) The declining autopsy rate and clinicians’ attitudes. Ulster Med J 69:83–89PubMedPubMedCentral
7.
go back to reference Oluwasola OA, Fawole OI, Otegbayo AJ, Ogun GO, Adebamowo CA, Bamigboye AE (2009) The autopsy knowledge, attitude, and perceptions of doctors and relatives of the deceased. Arch Pathol Lab Med 133:78–82PubMed Oluwasola OA, Fawole OI, Otegbayo AJ, Ogun GO, Adebamowo CA, Bamigboye AE (2009) The autopsy knowledge, attitude, and perceptions of doctors and relatives of the deceased. Arch Pathol Lab Med 133:78–82PubMed
8.
go back to reference Ordi J, Ismail MR, Carrilho C et al (2009) Clinico-pathological discrepancies in the diagnosis of causes of maternal death in sub-Saharan Africa: retrospective analysis. PLoSMed 6:e1000036 Ordi J, Ismail MR, Carrilho C et al (2009) Clinico-pathological discrepancies in the diagnosis of causes of maternal death in sub-Saharan Africa: retrospective analysis. PLoSMed 6:e1000036
9.
go back to reference Kuijpers CC, Fronczek J, Van De Goot FR et al (2014) The value of autopsies in the era of high-tech medicine: discrepant findings persist. J Clin Pathol 67:512–519CrossRef Kuijpers CC, Fronczek J, Van De Goot FR et al (2014) The value of autopsies in the era of high-tech medicine: discrepant findings persist. J Clin Pathol 67:512–519CrossRef
10.
go back to reference Sonnemans LJP, Kubat B, Prokop M, Klein WM (2018) Can virtual autopsy with postmortem CT improve clinical diagnosis of cause of death? A retrospective observational cohort study in a Dutch tertiary referral centre. BMJ Open 8:e018834CrossRef Sonnemans LJP, Kubat B, Prokop M, Klein WM (2018) Can virtual autopsy with postmortem CT improve clinical diagnosis of cause of death? A retrospective observational cohort study in a Dutch tertiary referral centre. BMJ Open 8:e018834CrossRef
11.
go back to reference Castillo P, Martinez MJ, Ussene E et al (2016) Validity of a minimally invasive autopsy for cause of death determination in adults in Mozambique: an observational study. PLoS Med 13:e1002171CrossRef Castillo P, Martinez MJ, Ussene E et al (2016) Validity of a minimally invasive autopsy for cause of death determination in adults in Mozambique: an observational study. PLoS Med 13:e1002171CrossRef
12.
go back to reference Menendez C, Castillo P, Martínez MJ, Jordao D, Lovane L, Ismail MR, Carrilho C, Lorenzoni C, Fernandes F, Nhampossa T, Hurtado JC, Navarro M, Casas I, Santos Ritchie P, Bandeira S, Mocumbi S, Jaze Z, Mabota F, Munguambe K, Maixenchs M, Sanz A, Mandomando I, Nadal A, Goncé A, Muñoz-Almagro C, Quintó L, Vila J, Macete E, Alonso P, Ordi J, Bassat Q (2017) Validity of a minimally invasive autopsy for cause of death determination in stillborn babies and neonates in Mozambique: an observational study. PLoS Med 14:e1002318CrossRef Menendez C, Castillo P, Martínez MJ, Jordao D, Lovane L, Ismail MR, Carrilho C, Lorenzoni C, Fernandes F, Nhampossa T, Hurtado JC, Navarro M, Casas I, Santos Ritchie P, Bandeira S, Mocumbi S, Jaze Z, Mabota F, Munguambe K, Maixenchs M, Sanz A, Mandomando I, Nadal A, Goncé A, Muñoz-Almagro C, Quintó L, Vila J, Macete E, Alonso P, Ordi J, Bassat Q (2017) Validity of a minimally invasive autopsy for cause of death determination in stillborn babies and neonates in Mozambique: an observational study. PLoS Med 14:e1002318CrossRef
13.
go back to reference Castillo P, Hurtado JC, Martínez MJ, Jordao D, Lovane L, Ismail MR, Carrilho C, Lorenzoni C, Fernandes F, Mocumbi S, Jaze ZO, Mabota F, Cossa A, Mandomando I, Cisteró P, Mayor A, Navarro M, Casas I, Vila J, Maixenchs M, Munguambe K, Sanz A, Quintó L, Macete E, Alonso P, Bassat Q, Ordi J, Menéndez C (2017) Validity of a minimally invasive autopsy for cause of death determination in maternal deaths in Mozambique: an observational study. PLoS Med 14:e1002431CrossRef Castillo P, Hurtado JC, Martínez MJ, Jordao D, Lovane L, Ismail MR, Carrilho C, Lorenzoni C, Fernandes F, Mocumbi S, Jaze ZO, Mabota F, Cossa A, Mandomando I, Cisteró P, Mayor A, Navarro M, Casas I, Vila J, Maixenchs M, Munguambe K, Sanz A, Quintó L, Macete E, Alonso P, Bassat Q, Ordi J, Menéndez C (2017) Validity of a minimally invasive autopsy for cause of death determination in maternal deaths in Mozambique: an observational study. PLoS Med 14:e1002431CrossRef
14.
go back to reference Bassat Q, Castillo P, Martínez MJ, Jordao D, Lovane L, Hurtado JC, Nhampossa T, Santos Ritchie P, Bandeira S, Sambo C, Chicamba V, Ismail MR, Carrilho C, Lorenzoni C, Fernandes F, Cisteró P, Mayor A, Cossa A, Mandomando I, Navarro M, Casas I, Vila J, Munguambe K, Maixenchs M, Sanz A, Quintó L, Macete E, Alonso P, Menéndez C, Ordi J (2017) Validity of a minimally invasive autopsy tool for cause of death determination in pediatric deaths in Mozambique: an observational study. PLoS Med 14:e1002317CrossRef Bassat Q, Castillo P, Martínez MJ, Jordao D, Lovane L, Hurtado JC, Nhampossa T, Santos Ritchie P, Bandeira S, Sambo C, Chicamba V, Ismail MR, Carrilho C, Lorenzoni C, Fernandes F, Cisteró P, Mayor A, Cossa A, Mandomando I, Navarro M, Casas I, Vila J, Munguambe K, Maixenchs M, Sanz A, Quintó L, Macete E, Alonso P, Menéndez C, Ordi J (2017) Validity of a minimally invasive autopsy tool for cause of death determination in pediatric deaths in Mozambique: an observational study. PLoS Med 14:e1002317CrossRef
16.
go back to reference Castillo P, Ussene E, Ismail MR, Jordao D, Lovane L, Carrilho C, Lorenzoni C, Lacerda MV, Palhares A, Rodríguez-Carunchio L, Martínez MJ, Vila J, Bassat Q, Menéndez C, Ordi J (2015) Pathological methods applied to the investigation of causes of death in developing countries: minimally invasive autopsy approach. PLoSOne 10:e0132057CrossRef Castillo P, Ussene E, Ismail MR, Jordao D, Lovane L, Carrilho C, Lorenzoni C, Lacerda MV, Palhares A, Rodríguez-Carunchio L, Martínez MJ, Vila J, Bassat Q, Menéndez C, Ordi J (2015) Pathological methods applied to the investigation of causes of death in developing countries: minimally invasive autopsy approach. PLoSOne 10:e0132057CrossRef
17.
go back to reference Hutchins GM (1994) Practice guidelines for autopsy pathology. Autopsy performance. Autopsy Committee of the College of American Pathologists. Arch Pathol Lab Med 118:19–25PubMed Hutchins GM (1994) Practice guidelines for autopsy pathology. Autopsy performance. Autopsy Committee of the College of American Pathologists. Arch Pathol Lab Med 118:19–25PubMed
18.
go back to reference Martinez MJ, Massora S, Mandomando I et al (2016) Infectious cause of death determination using minimally invasive autopsies in developing countries. Diagn Microbiol Infect Dis 84:80–86CrossRef Martinez MJ, Massora S, Mandomando I et al (2016) Infectious cause of death determination using minimally invasive autopsies in developing countries. Diagn Microbiol Infect Dis 84:80–86CrossRef
19.
go back to reference Da Silva RM, Da Silva Neto JR, Santos CS et al (2015) Fluorescent in situ hybridization of pre-incubated blood culture material for the rapid diagnosis of histoplasmosis. Med Mycol 53:160–164CrossRef Da Silva RM, Da Silva Neto JR, Santos CS et al (2015) Fluorescent in situ hybridization of pre-incubated blood culture material for the rapid diagnosis of histoplasmosis. Med Mycol 53:160–164CrossRef
20.
go back to reference Koepsell SA, Hinrichs SH, Iwen PC (2012) Applying a real-time PCR assay for Histoplasma capsulatum to clinically relevant formalin-fixed paraffin-embedded human tissue. J Clin Microbiol 50:3395–3397CrossRef Koepsell SA, Hinrichs SH, Iwen PC (2012) Applying a real-time PCR assay for Histoplasma capsulatum to clinically relevant formalin-fixed paraffin-embedded human tissue. J Clin Microbiol 50:3395–3397CrossRef
22.
go back to reference World Health Organization. International classification of diseases (ICD-10): international statistica classification of diseases and related health problems. 10th revision. 5th ed. Geneva: World Health Organization, http://apps.who.int/classifications/icd10/browse/2016/en (2016, accessed 15 May 2018) World Health Organization. International classification of diseases (ICD-10): international statistica classification of diseases and related health problems. 10th revision. 5th ed. Geneva: World Health Organization, http://​apps.​who.​int/​classifications/​icd10/​browse/​2016/​en (2016, accessed 15 May 2018)
23.
go back to reference Goldman L, Sayson R, Robbins S, Cohn LH, Bettmann M, Weisberg M (1983) The value of the autopsy in three medical eras. NEnglJMed 308:1000–1005CrossRef Goldman L, Sayson R, Robbins S, Cohn LH, Bettmann M, Weisberg M (1983) The value of the autopsy in three medical eras. NEnglJMed 308:1000–1005CrossRef
24.
go back to reference Battle RM, Pathak D, Humble CG, Key CR, Vanatta PR, Hill RB, Anderson RE (1987) Factors influencing discrepancies between premortem and postmortem diagnoses. JAMA 258:339–344CrossRef Battle RM, Pathak D, Humble CG, Key CR, Vanatta PR, Hill RB, Anderson RE (1987) Factors influencing discrepancies between premortem and postmortem diagnoses. JAMA 258:339–344CrossRef
25.
go back to reference Grinberg LT, Ferraz da Silva LF, Galtarossa Xavier AC, Nascimento Saldiva PH, Mauad T (2008) Clinico-pathological discrepancies in the diagnoses of solid malignancies. Pathol Res Pract 204:867–873CrossRef Grinberg LT, Ferraz da Silva LF, Galtarossa Xavier AC, Nascimento Saldiva PH, Mauad T (2008) Clinico-pathological discrepancies in the diagnoses of solid malignancies. Pathol Res Pract 204:867–873CrossRef
26.
go back to reference Landis JR, Koch GG (1977) The measurement of observer agreement for categorical data. Biometrics 33:159–174CrossRef Landis JR, Koch GG (1977) The measurement of observer agreement for categorical data. Biometrics 33:159–174CrossRef
27.
go back to reference Békondi C, Bernede C, Passone N, Minssart P, Kamalo C, Mbolidi D, Germani Y (2006) Primary and opportunistic pathogens associated with meningitis in adults in Bangui, Central African Republic, in relation to human immunodeficiency virus serostatus. Int J Infect Dis 10:387–395CrossRef Békondi C, Bernede C, Passone N, Minssart P, Kamalo C, Mbolidi D, Germani Y (2006) Primary and opportunistic pathogens associated with meningitis in adults in Bangui, Central African Republic, in relation to human immunodeficiency virus serostatus. Int J Infect Dis 10:387–395CrossRef
28.
go back to reference Adenis A, Nacher M, Hanf M, Vantilcke V, Boukhari R, Blachet D, Demar M, Aznar C, Carme B, Couppie P (2014) HIV-associated histoplasmosis early mortality and incidence trends: from neglect to priority. PLoS Negl Trop Dis 8:e3100CrossRef Adenis A, Nacher M, Hanf M, Vantilcke V, Boukhari R, Blachet D, Demar M, Aznar C, Carme B, Couppie P (2014) HIV-associated histoplasmosis early mortality and incidence trends: from neglect to priority. PLoS Negl Trop Dis 8:e3100CrossRef
29.
go back to reference de Souza SLS, Feitoza PVS, de Araújo JR et al Causes of death among patients with acquired immunodeficiency syndrome autopsied at the Tropical Medicine Foundation of Amazonas. Rev Soc Bras Med Trop 41:247–251 de Souza SLS, Feitoza PVS, de Araújo JR et al Causes of death among patients with acquired immunodeficiency syndrome autopsied at the Tropical Medicine Foundation of Amazonas. Rev Soc Bras Med Trop 41:247–251
30.
go back to reference da Silva Ferreira B, de Araújo Filho JA, Matos Pereira N, de Miranda Godoy L, Borges Lamounier B, Dias Nunes E, Espíndola Rosa L (2017) Disseminated histoplasmosis in AIDS patients: an urban disease. Experience in a metropolis in the middle east of Brasil. Infez Med 25:258–262PubMed da Silva Ferreira B, de Araújo Filho JA, Matos Pereira N, de Miranda Godoy L, Borges Lamounier B, Dias Nunes E, Espíndola Rosa L (2017) Disseminated histoplasmosis in AIDS patients: an urban disease. Experience in a metropolis in the middle east of Brasil. Infez Med 25:258–262PubMed
31.
go back to reference Adenis AA, Valdes A, Cropet C, McCotter OZ, Derado G, Couppie P, Chiller T, Nacher M (2018) Burden of HIV-associated histoplasmosis compared with tuberculosis in Latin America: a modelling study. Lancet Infect Dis 18:1150–1159CrossRef Adenis AA, Valdes A, Cropet C, McCotter OZ, Derado G, Couppie P, Chiller T, Nacher M (2018) Burden of HIV-associated histoplasmosis compared with tuberculosis in Latin America: a modelling study. Lancet Infect Dis 18:1150–1159CrossRef
32.
go back to reference Pasqualotto AC, Quieroz-Telles F (2018) Histoplasmosis dethrones tuberculosis in Latin America. Lancet Infect Dis 18:1058–1060CrossRef Pasqualotto AC, Quieroz-Telles F (2018) Histoplasmosis dethrones tuberculosis in Latin America. Lancet Infect Dis 18:1058–1060CrossRef
33.
go back to reference Lanjewar DN (2011) The spectrum of clinical and pathological manifestations of AIDS in a consecutive series of 236 autopsied cases in Mumbai, India. Pathol Res Int 2011:547618CrossRef Lanjewar DN (2011) The spectrum of clinical and pathological manifestations of AIDS in a consecutive series of 236 autopsied cases in Mumbai, India. Pathol Res Int 2011:547618CrossRef
34.
go back to reference de Martel C, Maucort-Boulch D, Plummer M, Franceschi S (2015) World-wide relative contribution of hepatitis B and C viruses in hepatocellular carcinoma. Hepatology 62:1190–1200CrossRef de Martel C, Maucort-Boulch D, Plummer M, Franceschi S (2015) World-wide relative contribution of hepatitis B and C viruses in hepatocellular carcinoma. Hepatology 62:1190–1200CrossRef
35.
go back to reference Debes JD, Chan AJ, Balderramo D, Kikuchi L, Gonzalez Ballerga E, Prieto JE, Tapias M, Idrovo V, Davalos MB, Cairo F, Barreyro FJ, Paredes S, Hernandez N, Avendaño K, Diaz Ferrer J, Yang JD, Carrera E, Garcia JA, Mattos AZ, Hirsch BS, Gonçalves PT, Carrilho FJ, Roberts LR (2018) Hepatocellular carcinoma in South America: evaluation of risk factors, demographics and therapy. Liver Int 38:136–143CrossRef Debes JD, Chan AJ, Balderramo D, Kikuchi L, Gonzalez Ballerga E, Prieto JE, Tapias M, Idrovo V, Davalos MB, Cairo F, Barreyro FJ, Paredes S, Hernandez N, Avendaño K, Diaz Ferrer J, Yang JD, Carrera E, Garcia JA, Mattos AZ, Hirsch BS, Gonçalves PT, Carrilho FJ, Roberts LR (2018) Hepatocellular carcinoma in South America: evaluation of risk factors, demographics and therapy. Liver Int 38:136–143CrossRef
Metadata
Title
Performance of the minimally invasive autopsy tool for cause of death determination in adult deaths from the Brazilian Amazon: an observational study
Authors
Antonio E. M. Palhares
Luiz Ferreira
Monique Freire
Paola Castillo
Miguel J Martínez
Juan Carlos Hurtado
Natalia Rakislova
Rosauro Varo
Mireia Navarro
Isaac Casas
Jordi Vila
Wuelton M. Monteiro
Ariadna Sanz
Llorenç Quintó
Fabiola Fernandes
Carla Carrilho
Clara Menéndez
Jaume Ordi
Quique Bassat
Marcus Lacerda
Publication date
01-11-2019
Publisher
Springer Berlin Heidelberg
Published in
Virchows Archiv / Issue 5/2019
Print ISSN: 0945-6317
Electronic ISSN: 1432-2307
DOI
https://doi.org/10.1007/s00428-019-02602-z

Other articles of this Issue 5/2019

Virchows Archiv 5/2019 Go to the issue