Published in:
01-04-2009 | Letter to The Editor
Author’s Response to Letter to the Editor
Author:
Melinda Maggard
Published in:
Digestive Diseases and Sciences
|
Issue 4/2009
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Excerpt
While simulation methods have their strengths, they have important non-real-world limitations. Many assumptions in the analysis that Metze and Adam refer to in their letter to the editor lack some clinical face validity. The authors base their simulation models on a modest number of select cases (upper rectum and sigmoid colon), a total of 6 cases of T1 lesions and 34 cases for T2 lesions [
1]. All patients were node positive and they modeled that nodes were randomly selected from 23 nodes for the T1 lesions and 17 for the T2 lesions. …