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Published in: Digestive Diseases and Sciences 4/2009

01-04-2009 | Letter to The Editor

Author’s Response to Letter to the Editor

Author: Melinda Maggard

Published in: Digestive Diseases and Sciences | Issue 4/2009

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Excerpt

While simulation methods have their strengths, they have important non-real-world limitations. Many assumptions in the analysis that Metze and Adam refer to in their letter to the editor lack some clinical face validity. The authors base their simulation models on a modest number of select cases (upper rectum and sigmoid colon), a total of 6 cases of T1 lesions and 34 cases for T2 lesions [1]. All patients were node positive and they modeled that nodes were randomly selected from 23 nodes for the T1 lesions and 17 for the T2 lesions. …
Literature
1.
go back to reference Leibl S, Tsybrovskyy O, Denk H. How many lymph nodes are necessary to stage early and advanced adenocarcinoma of the sigmoid colon and upper rectum? Virchows Arch. 2003;443(2):133–138.PubMedCrossRef Leibl S, Tsybrovskyy O, Denk H. How many lymph nodes are necessary to stage early and advanced adenocarcinoma of the sigmoid colon and upper rectum? Virchows Arch. 2003;443(2):133–138.PubMedCrossRef
Metadata
Title
Author’s Response to Letter to the Editor
Author
Melinda Maggard
Publication date
01-04-2009
Publisher
Springer US
Published in
Digestive Diseases and Sciences / Issue 4/2009
Print ISSN: 0163-2116
Electronic ISSN: 1573-2568
DOI
https://doi.org/10.1007/s10620-008-0655-6

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