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Published in: Clinical Reviews in Allergy & Immunology 3/2011

01-12-2011

Atopic Dermatitis and the Nervous System

Author: Laurent Misery

Published in: Clinical Reviews in Allergy & Immunology | Issue 3/2011

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Abstract

Due to the narrow associations between the skin, immune system, and nervous system, nerve endings are very important in the pathophysiology of inflammatory dermatoses and especially in atopic dermatitis. Many neurotransmitters and nerve growth factors that are released in blood or skin are involved in neurogenic inflammation, which dramatically enhance the inflammation induced by immune cells. During times of stress, their release is highly enhanced. In atopic dermatitis lesions, there are many specific changes in skin neurobiology and neurophysiology. These interesting data suggest that novel therapeutic possibilities can be imagined.
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Metadata
Title
Atopic Dermatitis and the Nervous System
Author
Laurent Misery
Publication date
01-12-2011
Publisher
Humana Press Inc
Published in
Clinical Reviews in Allergy & Immunology / Issue 3/2011
Print ISSN: 1080-0549
Electronic ISSN: 1559-0267
DOI
https://doi.org/10.1007/s12016-010-8225-z

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