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Published in: BMC Geriatrics 1/2024

Open Access 01-12-2024 | Research

Association of two geriatric treatment systems with anti-osteoporotic drug treatment and second hip fracture in patients with an index hip fracture: retrospective cohort study

Authors: Kilian Rapp, Patrick Roigk, Clemens Becker, Chris Todd, Martin Rehm, Dietrich Rothenbacher, Claudia Konnopka, Hans-Helmut König, Thomas Friess, Gisela Büchele

Published in: BMC Geriatrics | Issue 1/2024

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Abstract

Background

In Germany, geriatricians deliver acute geriatric care during acute hospital stay and post-acute rehabilitation after transfer to a rehabilitation clinic. The rate patients receive acute geriatric care (AGC) or are transferred to post-acute rehabilitation (TPR) differs between hospitals. This study analyses the association between the two geriatric treatment systems (AGC, TPR) and second hip fracture in patients following an index hip fracture.

Methods

Nationwide health insurance data are used to identify the rate of AGC and TPR per hospital following hip fracture surgery in patients aged ≥ 80 years. Outcomes are a second hip fracture after surgery or after discharge within 180 or 360 days and new specific anti-osteoporotic drugs. Cox proportional hazard models and generalised linear models are applied.

Results

Data from 29,096 hip fracture patients from 652 hospitals were analysed. AGC and TPR are not associated with second hip fracture when follow-up started after surgery. However, during the first months after discharge patients from hospitals with no AGC or low rates of TPR have higher rates of second hip fracture than patients from hospitals with high rates of AGC or high rates of TPR (Hazard Ratio (95% CI) 1.35 (1.01–1.80) or 1.35 (1.03–1.79), respectively). Lower rates of AGC are associated with lower probabilities of new prescriptions of specific anti-osteoporotic drugs.

Conclusions

Our study suggests beneficial relationships of geriatric treatment after hip fracture with a) the risk of second hip fractures during the first months after discharge and b) an improvement of anti-osteoporotic drug treatment.
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Literature
1.
go back to reference Johansson H, Siggeirsdóttir K, Harvey NC, Odén A, Gudnason V, McCloskey E, et al. Imminent risk of fracture after fracture. Osteoporos Int J Establ Result Coop Eur Found Osteoporos Natl Osteoporos Found USA. 2017;28:775–80.CrossRef Johansson H, Siggeirsdóttir K, Harvey NC, Odén A, Gudnason V, McCloskey E, et al. Imminent risk of fracture after fracture. Osteoporos Int J Establ Result Coop Eur Found Osteoporos Natl Osteoporos Found USA. 2017;28:775–80.CrossRef
2.
go back to reference Wong RMY, Wong PY, Liu C, Wong HW, Chung YL, Chow SKH, et al. The imminent risk of a fracture-existing worldwide data: a systematic review and meta-analysis. Osteoporos Int J Establ Result Coop Eur Found Osteoporos Natl Osteoporos Found USA. 2022;33:2453–66.CrossRef Wong RMY, Wong PY, Liu C, Wong HW, Chung YL, Chow SKH, et al. The imminent risk of a fracture-existing worldwide data: a systematic review and meta-analysis. Osteoporos Int J Establ Result Coop Eur Found Osteoporos Natl Osteoporos Found USA. 2022;33:2453–66.CrossRef
3.
go back to reference Pisani P, Renna MD, Conversano F, Casciaro E, Di Paola M, Quarta E, et al. Major osteoporotic fragility fractures: Risk factor updates and societal impact. World J Orthop. 2016;7:171–81.CrossRefPubMedPubMedCentral Pisani P, Renna MD, Conversano F, Casciaro E, Di Paola M, Quarta E, et al. Major osteoporotic fragility fractures: Risk factor updates and societal impact. World J Orthop. 2016;7:171–81.CrossRefPubMedPubMedCentral
4.
go back to reference Rapp K, Lamb SE, Klenk J, Kleiner A, Heinrich S, König H-H, et al. Fractures after nursing home admission: incidence and potential consequences. Osteoporos Int J Establ Result Coop Eur Found Osteoporos Natl Osteoporos Found USA. 2009;20:1775–83.CrossRef Rapp K, Lamb SE, Klenk J, Kleiner A, Heinrich S, König H-H, et al. Fractures after nursing home admission: incidence and potential consequences. Osteoporos Int J Establ Result Coop Eur Found Osteoporos Natl Osteoporos Found USA. 2009;20:1775–83.CrossRef
5.
go back to reference Rapp K, Cameron ID, Becker C, Kleiner A, Eckardt M, König H-H, et al. Femoral fracture rates after discharge from the hospital to the community. J Bone Miner Res Off J Am Soc Bone Miner Res. 2013;28:821–7.CrossRef Rapp K, Cameron ID, Becker C, Kleiner A, Eckardt M, König H-H, et al. Femoral fracture rates after discharge from the hospital to the community. J Bone Miner Res Off J Am Soc Bone Miner Res. 2013;28:821–7.CrossRef
6.
go back to reference Blain H, Masud T, Dargent-Molina P, Martin FC, Rosendahl E, van der Velde N, et al. A comprehensive fracture prevention strategy in older adults: the European Union Geriatric Medicine Society (EUGMS) statement. Aging Clin Exp Res. 2016;28:797–803.CrossRefPubMed Blain H, Masud T, Dargent-Molina P, Martin FC, Rosendahl E, van der Velde N, et al. A comprehensive fracture prevention strategy in older adults: the European Union Geriatric Medicine Society (EUGMS) statement. Aging Clin Exp Res. 2016;28:797–803.CrossRefPubMed
7.
go back to reference Ranhoff AH, Saltvedt I, Frihagen F, Raeder J, Maini S, Sletvold O. Interdisciplinary care of hip fractures: Orthogeriatric models, alternative models, interdisciplinary teamwork. Best Pract Res Clin Rheumatol. 2019;33:205–26.CrossRefPubMed Ranhoff AH, Saltvedt I, Frihagen F, Raeder J, Maini S, Sletvold O. Interdisciplinary care of hip fractures: Orthogeriatric models, alternative models, interdisciplinary teamwork. Best Pract Res Clin Rheumatol. 2019;33:205–26.CrossRefPubMed
8.
go back to reference Hawley S, Javaid MK, Prieto-Alhambra D, Lippett J, Sheard S, Arden NK, et al. Clinical effectiveness of orthogeriatric and fracture liaison service models of care for hip fracture patients: population-based longitudinal study. Age Ageing. 2016;45:236–42.CrossRefPubMedPubMedCentral Hawley S, Javaid MK, Prieto-Alhambra D, Lippett J, Sheard S, Arden NK, et al. Clinical effectiveness of orthogeriatric and fracture liaison service models of care for hip fracture patients: population-based longitudinal study. Age Ageing. 2016;45:236–42.CrossRefPubMedPubMedCentral
9.
go back to reference Moyet J, Deschasse G, Marquant B, Mertl P, Bloch F. Which is the optimal orthogeriatric care model to prevent mortality of elderly subjects post hip fractures? A systematic review and meta-analysis based on current clinical practice. Int Orthop. 2019;43:1449–54.CrossRefPubMed Moyet J, Deschasse G, Marquant B, Mertl P, Bloch F. Which is the optimal orthogeriatric care model to prevent mortality of elderly subjects post hip fractures? A systematic review and meta-analysis based on current clinical practice. Int Orthop. 2019;43:1449–54.CrossRefPubMed
10.
go back to reference Grigoryan KV, Javedan H, Rudolph JL. Orthogeriatric care models and outcomes in hip fracture patients: a systematic review and meta-analysis. J Orthop Trauma. 2014;28:e49-55.CrossRefPubMedPubMedCentral Grigoryan KV, Javedan H, Rudolph JL. Orthogeriatric care models and outcomes in hip fracture patients: a systematic review and meta-analysis. J Orthop Trauma. 2014;28:e49-55.CrossRefPubMedPubMedCentral
11.
go back to reference Van Heghe A, Mordant G, Dupont J, Dejaeger M, Laurent MR, Gielen E. Effects of Orthogeriatric Care Models on Outcomes of Hip Fracture Patients: A Systematic Review and Meta-Analysis. Calcif Tissue Int. 2022;110:162–84.CrossRefPubMed Van Heghe A, Mordant G, Dupont J, Dejaeger M, Laurent MR, Gielen E. Effects of Orthogeriatric Care Models on Outcomes of Hip Fracture Patients: A Systematic Review and Meta-Analysis. Calcif Tissue Int. 2022;110:162–84.CrossRefPubMed
12.
go back to reference Patel JN, Klein DS, Sreekumar S, Liporace FA, Yoon RS. Outcomes in Multidisciplinary Team-based Approach in Geriatric Hip Fracture Care: A Systematic Review. J Am Acad Orthop Surg. 2020;28:128–33.CrossRefPubMed Patel JN, Klein DS, Sreekumar S, Liporace FA, Yoon RS. Outcomes in Multidisciplinary Team-based Approach in Geriatric Hip Fracture Care: A Systematic Review. J Am Acad Orthop Surg. 2020;28:128–33.CrossRefPubMed
13.
go back to reference Wang Y, Tang J, Zhou F, Yang L, Wu J. Comprehensive geriatric care reduces acute perioperative delirium in elderly patients with hip fractures: A meta-analysis. Medicine (Baltimore). 2017;96: e7361.CrossRefPubMed Wang Y, Tang J, Zhou F, Yang L, Wu J. Comprehensive geriatric care reduces acute perioperative delirium in elderly patients with hip fractures: A meta-analysis. Medicine (Baltimore). 2017;96: e7361.CrossRefPubMed
14.
go back to reference Van Camp L, Dejaeger M, Tournoy J, Gielen E, Laurent MR. Association of orthogeriatric care models with evaluation and treatment of osteoporosis: a systematic review and meta-analysis. Osteoporos Int J Establ Result Coop Eur Found Osteoporos Natl Osteoporos Found USA. 2020;31:2083–92.CrossRef Van Camp L, Dejaeger M, Tournoy J, Gielen E, Laurent MR. Association of orthogeriatric care models with evaluation and treatment of osteoporosis: a systematic review and meta-analysis. Osteoporos Int J Establ Result Coop Eur Found Osteoporos Natl Osteoporos Found USA. 2020;31:2083–92.CrossRef
15.
go back to reference Gregersen M, Mørch MM, Hougaard K, Damsgaard EM. Geriatric intervention in elderly patients with hip fracture in an orthopedic ward. J Inj Violence Res. 2012;4:45–51.CrossRefPubMedPubMedCentral Gregersen M, Mørch MM, Hougaard K, Damsgaard EM. Geriatric intervention in elderly patients with hip fracture in an orthopedic ward. J Inj Violence Res. 2012;4:45–51.CrossRefPubMedPubMedCentral
16.
go back to reference Duaso E, Formiga F, Marimón P, Sandiumenge M, Salgado MT, Murga V, et al. Advantages of care for patients with hip fractures in the acute geriatric unit: Hip study Anoia. Geriatr Gerontol Int. 2018;18:407–14.CrossRefPubMed Duaso E, Formiga F, Marimón P, Sandiumenge M, Salgado MT, Murga V, et al. Advantages of care for patients with hip fractures in the acute geriatric unit: Hip study Anoia. Geriatr Gerontol Int. 2018;18:407–14.CrossRefPubMed
17.
go back to reference Becker C, Rapp K, Rothenbacher D, Schulz C, König H-H, Büchele G. Acute care models for hip fracture treatment vs post-acute rehabilitation services in older adults after hip fracture: A comparative claims data analysis from Germany. J Rehabil Med. 2020;52:jrm00024.PubMed Becker C, Rapp K, Rothenbacher D, Schulz C, König H-H, Büchele G. Acute care models for hip fracture treatment vs post-acute rehabilitation services in older adults after hip fracture: A comparative claims data analysis from Germany. J Rehabil Med. 2020;52:jrm00024.PubMed
18.
go back to reference Bundesverband Geriatrie e. V. Weißbuch Geriatrie, Zukunftssicherheit der Geriatrie - Konzept und Bedarfszahlen. 4th edition. Kohlhammer; 2023. Bundesverband Geriatrie e. V. Weißbuch Geriatrie, Zukunftssicherheit der Geriatrie - Konzept und Bedarfszahlen. 4th edition. Kohlhammer; 2023.
19.
go back to reference Sieber CC. The elderly patient–who is that? Internist. 2007;48(1190):1192–4. Sieber CC. The elderly patient–who is that? Internist. 2007;48(1190):1192–4.
20.
22.
go back to reference Becker C, Leistner K, Nikolaus T. Introducing a statutory insurance system for long-term care (Pflegeversicherung) in Germany. Michel JP, Rubenstein LZ, Vellas BJ, Albarede JL: Geriatric Programs and departments around the world. Paris-New York: Serdi-Springer; 1998; p. 55–64. Becker C, Leistner K, Nikolaus T. Introducing a statutory insurance system for long-term care (Pflegeversicherung) in Germany. Michel JP, Rubenstein LZ, Vellas BJ, Albarede JL: Geriatric Programs and departments around the world. Paris-New York: Serdi-Springer; 1998; p. 55–64.
23.
go back to reference Moja L, Piatti A, Pecoraro V, Ricci C, Virgili G, Salanti G, et al. Timing matters in hip fracture surgery: patients operated within 48 hours have better outcomes. A meta-analysis and meta-regression of over 190,000 patients. PloS One. 2012;7:46175.CrossRef Moja L, Piatti A, Pecoraro V, Ricci C, Virgili G, Salanti G, et al. Timing matters in hip fracture surgery: patients operated within 48 hours have better outcomes. A meta-analysis and meta-regression of over 190,000 patients. PloS One. 2012;7:46175.CrossRef
24.
go back to reference Huber CA, Szucs TD, Rapold R, Reich O. Identifying patients with chronic conditions using pharmacy data in Switzerland: an updated mapping approach to the classification of medications. BMC Public Health. 2013;13:1030.CrossRefPubMedPubMedCentral Huber CA, Szucs TD, Rapold R, Reich O. Identifying patients with chronic conditions using pharmacy data in Switzerland: an updated mapping approach to the classification of medications. BMC Public Health. 2013;13:1030.CrossRefPubMedPubMedCentral
25.
go back to reference Prestmo A, Hagen G, Sletvold O, Helbostad JL, Thingstad P, Taraldsen K, et al. Comprehensive geriatric care for patients with hip fractures: a prospective, randomised, controlled trial. Lancet Lond Engl. 2015;385:1623–33.CrossRef Prestmo A, Hagen G, Sletvold O, Helbostad JL, Thingstad P, Taraldsen K, et al. Comprehensive geriatric care for patients with hip fractures: a prospective, randomised, controlled trial. Lancet Lond Engl. 2015;385:1623–33.CrossRef
26.
go back to reference Schoeneberg C, Pass B, Volland R, Knobe M, Eschbach D, Ketter V, et al. Four-month outcome after proximal femur fractures and influence of early geriatric rehabilitation: data from the German Centres of Geriatric Trauma DGU. Arch Osteoporos. 2021;16:68.CrossRefPubMed Schoeneberg C, Pass B, Volland R, Knobe M, Eschbach D, Ketter V, et al. Four-month outcome after proximal femur fractures and influence of early geriatric rehabilitation: data from the German Centres of Geriatric Trauma DGU. Arch Osteoporos. 2021;16:68.CrossRefPubMed
27.
go back to reference Montero-Odasso M, van der Velde N, Martin FC, Petrovic M, Tan MP, Ryg J, et al. World guidelines for falls prevention and management for older adults: a global initiative. Age Ageing. 2022;51:afac205.CrossRefPubMedPubMedCentral Montero-Odasso M, van der Velde N, Martin FC, Petrovic M, Tan MP, Ryg J, et al. World guidelines for falls prevention and management for older adults: a global initiative. Age Ageing. 2022;51:afac205.CrossRefPubMedPubMedCentral
Metadata
Title
Association of two geriatric treatment systems with anti-osteoporotic drug treatment and second hip fracture in patients with an index hip fracture: retrospective cohort study
Authors
Kilian Rapp
Patrick Roigk
Clemens Becker
Chris Todd
Martin Rehm
Dietrich Rothenbacher
Claudia Konnopka
Hans-Helmut König
Thomas Friess
Gisela Büchele
Publication date
01-12-2024
Publisher
BioMed Central
Published in
BMC Geriatrics / Issue 1/2024
Electronic ISSN: 1471-2318
DOI
https://doi.org/10.1186/s12877-024-04989-0

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