Published in:
Open Access
01-12-2013 | Research article
Association between smoking status and the parameters of vascular structure and function in adults: results from the EVIDENT study
Authors:
Jose I Recio-Rodriguez, Manuel A Gomez-Marcos, Maria C Patino Alonso, Carlos Martin-Cantera, Elisa Ibañez-Jalon, Amor Melguizo-Bejar, Luis Garcia-Ortiz
Published in:
BMC Cardiovascular Disorders
|
Issue 1/2013
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Abstract
Background
The present study analyses the relation between smoking status and the parameters used to assess vascular structure and function.
Methods
This cross-sectional, multi-centre study involved a random sample of 1553 participants from the EVIDENT study. Measurements: The smoking status, peripheral augmentation index and ankle-brachial index were measured in all participants. In a small subset of the main population (265 participants), the carotid intima-media thickness and pulse wave velocity were also measured.
Results
After controlling for the effect of age, sex and other risk factors, present smokers have higher values of carotid intima-media thickness (p = 0.011). Along the same lines, current smokers have higher values of pulse wave velocity and lower mean values of ankle-brachial index but without statistical significance in both cases.
Conclusions
Among the parameters of vascular structure and function analysed, only the IMT shows association with the smoking status, after adjusting for confounders.