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Calcified Tissue International
Published in: Calcified Tissue International 5/2013

01-11-2013 | Original Research

Association Between Aortic Calcification and the Risk of Osteoporosis in a Chinese Cohort: The Chongqing Osteoporosis Study

Authors: Rui Zhou, Huadong Zhou, Min Cui, Yanjiang Wang, Jun Tan, Darrell Sawmiller, Jianzhong Xu

Published in: Calcified Tissue International | Issue 5/2013

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Abstract

The aim of this study was to examine the relationship between aortic calcification (AC) and the risk of osteoporosis for a community of residents in China. We conducted a 5-year prospective study on 1,729 Chinese elderly subjects. An AC scale (ACS) was determined semiquantitatively from baseline lateral radiographs of the lumbar spine. Dual-energy X-ray absorptiometry was used to determine bone mineral density (BMD). Only subjects who completed the study were included in the final analysis; 432 subjects (25.0 %) developed osteoporosis. The BMD of vertebrae, femoral neck, and the total hip in the Q4 quartile of the ACS (ACS > 6) was lower when compared with the Q1 quartile (ACS = 0, p < 0.05). Cox proportional hazards model analysis showed that ACS (Q4), BMD, CTX, current smoking, and daily drinking were associated with increased risk of osteoporosis. A higher ACS was associated with an increased risk of osteoporosis in both women and men. The present study found that AC carried a higher risk of osteoporosis.
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Metadata
Title
Association Between Aortic Calcification and the Risk of Osteoporosis in a Chinese Cohort: The Chongqing Osteoporosis Study
Authors
Rui Zhou
Huadong Zhou
Min Cui
Yanjiang Wang
Jun Tan
Darrell Sawmiller
Jianzhong Xu
Publication date
01-11-2013
Publisher
Springer US
Published in
Calcified Tissue International / Issue 5/2013
Print ISSN: 0171-967X
Electronic ISSN: 1432-0827
DOI
https://doi.org/10.1007/s00223-013-9776-9

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