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01-11-2009 | Ultrasound

Assessment of parathyroid glands in hemodialysis patients by using color Doppler sonography

Authors: Umit Aksoy Ozcan, Ilay Oktay

Published in: European Radiology | Issue 11/2009

Abstract

The aim of this study was to assess the role of color and spectral Doppler ultrasound (CDU) in the evaluation of enlarged parathyroid glands in hemodialysis patients with secondary hyperparathyroidism. Fourteen hemodialysis patients with elevated intact parathyroid hormone (iPTH) levels were evaluated prospectively with CDU. The volume of each observed parathyroid gland and the spectral CDU data (velocities, resistance and pulsatility indices, systolic to diastolic ratio, and flow volume output (FVO)) were noted. The biochemical data (iPTH, calcium, phosphate levels), and CDU results were analyzed with the Spearman correlation test. Two patients were excluded, and 27 enlarged parathyroid glands were observed in 12 patients. The mean total volume of enlarged parathyroid glands per patient was 1.95 cm³ (0.06–5.5 cm³). Arterial supply was demonstrated in 78% (21/27) of enlarged parathyroid glands. Mean total FVO of enlarged glands per patient was 238.5 ml/min (620–0 ml/min) and mean iPTH level was 1,477 pg/ml (643–3,132 pg/ml). The positive correlations of total volume (p = 0.022), iPTH (p = 0.024), and FVO (p = 0.022) were statistically significant. In secondary hyperparathyroidism, total volume of the visualized enlarged parathyroid glands and the total of FVOs per patient are positively correlated with iPTH levels which may help clinical management and follow-up of end-stage renal disease patients.

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Title: Assessment of parathyroid glands in hemodialysis patients by using color Doppler sonography
Authors: Umit Aksoy Ozcan
Ilay Oktay
Publication date: 01-11-2009
Publisher: Springer-Verlag
Published in: European Radiology / Issue 11/2009
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-009-1462-y

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Assessment of parathyroid glands in hemodialysis patients by using color Doppler sonography

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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