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Annals of Surgical Oncology
Published in: Annals of Surgical Oncology 13/2021

01-12-2021 | ASO Author Reflections

ASO Author Reflections: Prognostic Role of a Coagulation Index for Patients with Esophageal Squamous Cell Cancer

Authors: Qifeng Wang, MD, Bangrong Cao, MD, Kun Mi, PhD

Published in: Annals of Surgical Oncology | Issue 13/2021

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Excerpt

The association between tumor progression and coagulation status has long been explored.1 Researchers have reported that certain platelet parameters and fibrinogen could be used as prognosis indicators for esophageal squamous cell carcinoma (ESCC);2 however, the majority of the studies focused on independent prognostic factors, and hence the potential prognostic role of the combination of these parameters has not been fully explored. There is an urgent need to identify these biomarkers as prognostic predictors and to develop an integrated prediction model for clinicians. …
Literature
1.
Wojtukiewicz MZ, Hempel D, Sierko E, et al. Thrombin-Unique coagulation system protein with multifaceted impacts on cancer and metastasis. Cancer Metastasis Rev. 2016;35:213–33.CrossRef
2.
Zhang F, Wang Y, Sun P, et al. Fibrinogen promotes malignant biological tumor behavior involving epithelial-mesenchymal transition via the p-AKT/p-mTOR pathway in esophageal squamous cell carcinoma. J Cancer Res Clin Oncol. 2017;143:2413–24.CrossRef
3.
4.
Arce M, Pinto MP, Galleguillos M, et al. Coagulation factor Xa promotes solid tumor growth, experimental metastasis and endothelial cell activation. Cancers (Basel). 2019;11:1103.CrossRef
Metadata
Title
ASO Author Reflections: Prognostic Role of a Coagulation Index for Patients with Esophageal Squamous Cell Cancer
Authors
Qifeng Wang, MD
Bangrong Cao, MD
Kun Mi, PhD
Publication date
01-12-2021
Publisher
Springer International Publishing
Published in
Annals of Surgical Oncology / Issue 13/2021
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-021-10267-9

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