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Indian Journal of Pediatrics
Published in: Indian Journal of Pediatrics 3/2024

13-09-2023 | Ascites | Review Article

An Approach to Investigations of Chronic Liver Disease

Authors: Aathira Ravindranath, Surender Kumar Yachha

Published in: Indian Journal of Pediatrics | Issue 3/2024

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Abstract

Chronic liver disease (CLD) in children is more diverse compared to adults with respect to the etiology, progression and response to therapy. After history and clinical examination, the first step is to confirm the presence of CLD with basic blood investigations and ultrasonography. Markers of portal hypertension are splenomegaly, increased portal vein diameter, thrombocytopenia and presence of varices on endoscopy. The next step is to evaluate the etiology of CLD which will depend on the age of the child and needs targeted investigations as metabolic and inherited causes predominate in early childhood. CLD progression ought to be monitored regularly and several non-invasive markers are available but they have to be evaluated further in children. Since CLD progresses, complications have to be detected early not only to initiate appropriate treatment but also to prognosticate.
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Metadata
Title
An Approach to Investigations of Chronic Liver Disease
Authors
Aathira Ravindranath
Surender Kumar Yachha
Publication date
13-09-2023
Publisher
Springer India
Published in
Indian Journal of Pediatrics / Issue 3/2024
Print ISSN: 0019-5456
Electronic ISSN: 0973-7693
DOI
https://doi.org/10.1007/s12098-023-04751-1

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