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Journal of Clinical Immunology
Published in: Journal of Clinical Immunology 1/2021

01-01-2021 | Arthritis | Letter to Editor

Deforming Polyarthritis in a North Indian Family—Clinical Expansion of STING-Associated Vasculopathy with Onset in Infancy (SAVI)

Authors: Gummadi Anjani, Ankur Kumar Jindal, Ashwini Prithvi, Anit Kaur, Amit Rawat, Madhubala Sharma, Bo Yuan, Ivan K. Chinn, Surjit Singh

Published in: Journal of Clinical Immunology | Issue 1/2021

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Excerpt

To the Editor, …
Appendix
Available only for authorised users
Literature
1.
Liu Y, Jesus AA, Marrero B, Yang D, Ramsey SE, Sanchez GAM, et al. Activated STING in a vascular and pulmonary syndrome. N Engl J Med. 2014;371(6):507–18.CrossRef
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Jeremiah N, Neven B, Gentili M, Callebaut I, Maschalidi S, Stolzenberg M-C, et al. Inherited STING-activating mutation underlies a familial inflammatory syndrome with lupus-like manifestations. J Clin Invest. 2014;124(12):5516–20.CrossRef
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Tang X, Xu H, Zhou C, Peng Y, Liu H, Liu J, et al. STING-associated vasculopathy with onset in infancy in three children with new clinical aspect and unsatisfactory therapeutic responses to tofacitinib. J Clin Immunol. 2020;40(1):114–22.CrossRef
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Cao Y, Jiang L-P. The challenge of diagnosing SAVI: case studies. Pediatr Allergy Immunol Pulmonol. 2019;32(4):167–72.CrossRef
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Clarke SLN, Robertson L, Rice GI, Seabra L, Hilliard TN, Crow YJ, et al. Type 1 interferonopathy presenting as juvenile idiopathic arthritis with interstitial lung disease: report of a new phenotype. Pediatr Rheumatol Online J. 2020;18(1):37.CrossRef
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Rodero MP, Tesser A, Bartok E, Rice GI, Della Mina E, Depp M, et al. Type I interferon-mediated autoinflammation due to DNase II deficiency. Nat Commun. 2017;8:2176.CrossRef
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Omoyinmi E, Melo Gomes S, Nanthapisal S, Woo P, Standing A, Eleftheriou D, et al. Stimulator of interferon genes-associated vasculitis of infancy. Arthritis Rheumatol Hoboken NJ. 2015;67(3):808.CrossRef
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Shoman W, El Chazli Y, ElSawy I, Aróstegui JI. First Egyptian patient with STING-associated vasculopathy with onset in infancy. Scand J Rheumatol. 2019;48(4):338–9.CrossRef
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Seo J, Kang J-A, Suh DI, Park E-B, Lee C-R, Choi SA, et al. Tofacitinib relieves symptoms of stimulator of interferon genes (STING)-associated vasculopathy with onset in infancy caused by 2 de novo variants in TMEM173. J Allergy Clin Immunol. 2017;139(4):1396–1399.e12.CrossRef
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Volpi S, Insalaco A, Caorsi R, Santori E, Messia V, Sacco O, et al. Efficacy and adverse events during Janus kinase inhibitor treatment of SAVI syndrome. J Clin Immunol. 2019;39(5):476–85.CrossRef
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Balci S, Ekinci RMK, de Jesus AA, Goldbach-Mansky R, Yilmaz M. Baricitinib experience on STING-associated vasculopathy with onset in infancy: a representative case from Turkey. Clin Immunol Orlando Fla. 2020;212:108273.CrossRef
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Sanchez GAM, Reinhardt A, Ramsey S, Wittkowski H, Hashkes PJ, Berkun Y, et al. JAK1/2 inhibition with baricitinib in the treatment of autoinflammatory interferonopathies. J Clin Invest. 2018;128(7):3041–52.CrossRef
Metadata
Title
Deforming Polyarthritis in a North Indian Family—Clinical Expansion of STING-Associated Vasculopathy with Onset in Infancy (SAVI)
Authors
Gummadi Anjani
Ankur Kumar Jindal
Ashwini Prithvi
Anit Kaur
Amit Rawat
Madhubala Sharma
Bo Yuan
Ivan K. Chinn
Surjit Singh
Publication date
01-01-2021
Publisher
Springer US
Published in
Journal of Clinical Immunology / Issue 1/2021
Print ISSN: 0271-9142
Electronic ISSN: 1573-2592
DOI
https://doi.org/10.1007/s10875-020-00872-w

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