Issue Special Issue 1/2014
Lupus 2014: New Targets, New Approaches
Content (53 Articles)
Moving lupus epidemiology forward: returning to the basics
Julia F Simard
Is prevention of systemic lupus erythematosus a goal?
Nancy J Olsen, David R Karp
Are patient ratings of interactions with providers and health plans associated with technical quality of care in systemic lupus erythematosus?
Edward Yelin, Laura Trupin, Jinoos Yazdany
Targeted delivery of PGE2 ameliorates autoimmune nephritis
Nino Kvirkvelia, Maggie McMenaminn, Michael P Madaio
Modeling the stochastic behavior of lupus
Derry C Roopenian, Elisabeth B Adkins, Giljun Park, Herbert C Morse III, Gregory W Carter
DNA repair in lupus
Jiadi Xu, Zubin Patel, Leah Kottyan, Richard A Gatti, Deborah K McCurdy, Kenneth M Kaufman, John B Harley
Impact of genetic variants on B-cell development and function in systemic lupus erythematosus
Karen Cerosaletti, Tania Habib, Richard James, Janice Chen, Melissa Pickett, Andrew Funk, Shan Wei, Jane H Buckner
Differential methylation of interferon-related genes is associated with autoantibody production in systemic lupus erythematosus
Sharon A Chung, Joanne Nititham, Emon Elboudwarej, Hong L Quach, Kimberly E Taylor, Lisa F Barcellos, Lindsey A Criswell
Subphenotype mapping in systemic lupus erythematosus identifies multiple novel loci associated with circulating interferon alpha
Silvia N Kariuki, Yogita Ghodke-Puranik, Jessica M Dorschner, Beverly S Chrabot, Jennifer A Kelly, Betty P Tsao, Robert P Kimberly, Marta E Alarcón-Riquelme, Chaim O Jacob, Lindsey A Criswell, Kathy L Sivils, Carl D Langefeld, John B Harley, Andrew D Skol, Timothy B Niewold
Fine mapping and functional study of the systemic lupus erythematosus-associated NMNAT2/SMG7 locus
Jian Zhao, Yun Deng, Jennifer M Grossman, Betty P Tsao
Impact of provider specialty on the diagnosis and management of systemic lupus erythematosus in the American Indian/Alaska Native population
John A McDougall, Charles G Helmick, S Sam Lim, Caroline Gordon, Elizabeth D Ferucci
Racial discrimination and disease damage among African American women with systemic lupus erythematosus
David H Chae, Christina M Drenkard, Tené T Lewis, S Sam Lim
The Scleroderma Patient-centered Intervention Network for conducting large-scale international trials of nonpharmacological interventions in scleroderma: a way ahead for lupus?
Brett D Thombs
Linking anti-Ro antibodies to fibrosis in congenital heart block: translation to a clinical trial
Jill P Buyon, Peter Izmirly, Deborah Friedman, Joshua Copel
Targeting IRF5 inhibition in human B cells: identification of new functional roles that implicate IRF5 in systemic lupus erythematosus B-cell pathology
Saurav De, Di Feng, Alisha Valdez, Amy Pitler, Betsy J Barnes
Platelet-derived microparticles serve as an important source of autoantigens and discriminate between levels of disease activity in systemic lupus erythematosus
Eric Boilard, Vincent Bissonnette, Valérie Garceau, Ellie Aghdassi, Nathalie Cloutier, Claudia Beaudoin, Davy Eng, Stacey Morrison, Paul R Fortin
Vimentin is a dominant target of in situ humoral immunity in human lupus tubulointerstitial nephritis
Marcus R Clark, Anthony Chang, Kichul Ko, Carole J Henry Dunand, Scott Henderson, Dan Brandt, Natalya Kaverina, Vladimir Liarski, Patrick C Wilson, Andrew J Kinloch
Aggregation of MAVS antiviral protein suggests a mechanism for increased type I interferon production in SLE
Wen-Hai Shao, Brendan A Hilliard, Daniel H Shu, Stephen O Priest, Philip L Cohen
Aberrant expansion of CXCR5+ memory CD4 T cells in patients with systemic lupus erythematosus
Jin-Young Choi, Sang Taek Kim, Insoo Kang, Joe Craft
Identification of stage-specific genes associated with lupus nephritis and response to remission induction in NZB/W and NZM2410 mice
Ramalingam Bethunaickan, Celine C Berthier, Weijia Zhang, Ridvan Eksi, Hong-Dong Li, Yuanfang Guan, Matthias Kretzler, Anne Davidson
Blimp-1 and systemic lupus erythematosus
Betty Diamond, Sun Jung Kim, Sebastian Schaetzle, George Georgiou
A role for cutaneous gamma delta T cells in the development of systemic lupus erythematosus
Mehran Ghoreishi, Jan P Dutz
Neutrophils - a complex story in the pathogenesis of systemic lupus erythematosus
Christian Lood, Keith Elkon
mTOR activation triggers proinflammatory expansion of IL-4-producing and necrosis-prone double-negative T cells, precedes flares, and serves as target for treatment in patients with systemic lupus erythematosus
Zhi-Wei Lai, Rebecca Borsuk, Ashwini Shadakshari, Jianghong Yu, Maha Dawood, Ricardo Garcia, Lisa Francis, Hajra Tily, Adam Bartos, Stephen V Faraone, Paul Phillips, Andras Perl
Elucidating the role of TNF-like weak inducer of apoptosis in the pathogenesis of cutaneous lupus
Jessica Doerner, Jing Wen, Yumin Xia, Adam Friedman, Jennifer Michaelson, Linda Burkly, Lan Wu, Chaim Putterman
Phenotypic consequences of TLR7-driven interferon and proinflammatory cytokine production in lupus
Westley H Reeves, Haoyang Zhuang, Yuan Xu, Shuhong Han, Hai Wang, Lijun Yang
Interferon-alpha and angiogenic dysregulation in pregnant lupus patients destined for preeclampsia
Danieli Andrade, Mimi Kim, Luz P Blanco, S Ananth Karumanchi, Gloria C Koo, Patricia Redecha, Kyriakos Kirou, Angela M Alvarez, Melissa J Mulla, Mary K Crow, Vikki M Abrahams, Mariana J Kaplan, Jane E Salmon
Protective natural autoantibodies and lupus pathogenesis
Gregg J Silverman
A serine/threonine phosphatase, PP2A, controls autoimmunity
George C Tsokos
The opportunity and imperative for point-of-care diagnostics in systemic lupus erythematosus
Marvin J Fritzler
Molecular characterization of proliferative lupus nephritis
Samir V Parikh, Huijuan Song, Jay Vance, Jianying Zing, Lianbo Yu, Ana Malvar, Brad H Rovin
Disease features and outcomes among US lupus patients of Hispanic origin and their Mestizo counterpart in Latina America
Manuel Ugarte-Gil, Guillermo J Pons-Estel, Daniel Wojdyla, Gerald McGwin Jr, Bernardo A Pons-Estel, Graciela S Alarcón
Elevated risk of chronic obstructive pulmonary disease in systemic lupus erythematosus: a population-based study
Antonio Avina-Zubieta, Mohsen Sadatsafavi, Eric C Sayre, John Esdaile
Cancer risk factors in systemic lupus erythematosus: multivariate regression analysis in 16,409 patients
Sasha Bernatsky, Rosalind Ramsey-Goldman, Jean-François Boivin, Lawrence Joseph, Michelle A Petri, Asad Zoma, Susan Manzi, Murray B Urowitz, Dafna D Gladman, Paul R Fortin, Ellen M Ginzler, Edward Yelin, Sang-Cheol Bae, Daniel J Wallace, Steven M Edworthy, Soren Jacobsen, Caroline Gordon, Mary A Dooley, Christine A Peschken, John G Hanly, Graciela S Alarcón, Ola Nived, Guillermo Ruiz-Irastorza, David Isenberg, Anisur Rahman, Torsten Witte, Cynthia Aranow, Diane L Kamen, Kristján Steinsson, Anca Askanase, Susan G Barr, Lindsey A Criswell, Gunnar Sturfelt, Neha M Patel, Jean-Luc Senécal, Michel Zummer, Janet E Pope, Stephanie Ensworth, Hani El-Gabalawy, Timothy McCarthy, Yvan St Pierre, Anne E Clarke
Serological features of systemic lupus erythematosus diagnosed after referral through a rheumatology triage system because of positive antinuclear antibodies
Marvin J Fritzler, Whitney Steber, Terri Lupton, Christie Fitch-Rogalsky, Liam Martin, Susan G Barr, Ann Clarke
Sociodemographics and epidemiology of serious infections requiring hospitalization among adults with systemic lupus erythematosus and lupus nephritis, 2000 to 2006
Candace H Feldman, Linda T Hiraki, Wolfgang Winkelmayer, Francisco M Marty, Jessica M Franklin, Daniel H Solomon, Seoyoung C Kim, Karen H Costenbader
Preliminary population-based incidence and prevalence estimates of systemic lupus erythematosus: the California Lupus Surveillance Project
Maria C Dall'Era, Kurt Snipes, Miriam Cisternas, Caroline Gordon, Charles G Helmick
Serious infection incidence rates in pediatric systemic lupus erythematosus according to medication use
Linda T Hiraki, Candace H Feldman, Mary Beth Son, Jessica M Franklin, Michael A Fischer, Daniel H Solomon, Seoyoung C Kim, Wolfgang C Winkelmayer, Karen H Costenbader
Smoking and secondhand smoke among patients with systemic lupus erythematosus and controls: associations with disease and disease damage
Samantha J Minkin, Stephanie N Slan, Gary S Gilkeson, Diane L Kamen
High mortality in North American Natives with systemic lupus erythematosus
Christine A Peschken, Ripneet Puar, Carol A Hitchon
Optimal determination of Physician Global Assessment of lupus disease activity: a pilot study
Cynthia Aranow
Outcome measures in systemic lupus erythematosus: constructing a meaningful response index from existing clinical trial data
Lindsy Forbess, Daniel Wallace, Mariko Ishimori, Michael Weisman
Significance of cerebrovascular reactivity in patients with systemic lupus erythematosus
Jason Lazar, Louis Salciciolli, Elina Malamed, Ellen M Ginzler
'Lupus headache': results from a prospective, international, inception cohort study
John G Hanly
Adverse pregnancy outcomes and subsequent risk of cardiovascular disease in women with systemic lupus erythematosus
Pin Lin, Elisa Rhew, Roberta B Ness, Alan Peaceman, Alan Dyer, David McPherson, George T Kondos, Daniel Edmundowicz, Kim Sutton-Tyrrell, Trina Thompson, Rosalind Ramsey-Goldman
Methodological quality of studies of end-stage renal disease risks in lupus nephritis
Maria Tektonidou, Abhijit Dasgupta, Michael Ward
Patient-Centered Outcomes Research Institute (PCORI) multisite project to develop treatment decision aids for racial/ethnic minorities with lupus nephritis
Jinoos Yazdany, Maria Dall'Era, Jasvinder Singh
Clinical response to belimumab in academic clinical practices
Arthi Reddy, XiaoQing Li, Jill P Buyon, Andrew G Franks, Richard A Furie, Diane L Kamen, Susan Manzi, Michelle Petri, Rosalind Ramsey-Goldman, Chung-E Tseng, Ronald F van Vollenhoven, Daniel J Wallace, Anca D Askanase
Eculizumab in recalcitrant antiphospholipid antibody syndrome
Ekaterini Zapantis, Richard Furie, Diane Horowitz
A comprehensive approach to identify approved drugs and treatments for repositioning as therapies for systemic lupus erythematosus
Amrie C Grammer, Matthew Ryals, Peter E Lipsky
Cluster analysis of longitudinal treatment patterns in patients newly diagnosed with systemic lupus erythematosus in the United States
Hong Kan, Saurabh Nagar, Jeetvan Patel, Daniel J Wallace, Charles Molta
Effects of atacicept on disease activity in patients with moderate to severe systemic lupus erythematosus: APRIL-SLE randomized trial
David Isenberg, Yong Li, Stephen Wax, David Wofsy, Caroline Gordon