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01-12-2007 | Letter

Are triple-negative tumours and basal-like breast cancer synonymous? Authors' response

Authors: Bas Kreike, Marc J van de Vijver

Published in: Breast Cancer Research | Issue 6/2007

Excerpt

We read with interest the issues raised by Rakha and colleagues [1] in their response to our recent research article [2], and we are pleased to address them. An important conclusion from our research article is that triple-negative breast cancer can be equated to basal-like breast cancer. In their letter, Rakha and colleagues [1] state that equating triple-negative phenotype (TNP) tumours with basal-like breast cancer is misleading and is not supported by the data we have presented. …

Rakha EA, Tan DSP, Foulkes WD, Ellis IO, Tutt A, Nielsen TO, Reis-Filho JS: Are triple-negative tumours and basal-like breast cancer synonymous?. Breast Cancer Res. 2007, 9: 404-10.1186/bcr1827.CrossRefPubMedPubMedCentral

Kreike B, van Kouwenhove M, Horlings H, Weigelt B, Peterse H, Bartelink H, van de Vijver MJ: Gene expression profiling and histopathological characterization of triple negative/basal-like breast carcinomas. Breast Cancer Res. 2007, 9: R65-10.1186/bcr1771.CrossRefPubMedPubMedCentral

Perou CM, Sørlie T, Eisen MB, van de Rijn M, Jeffrey SS, Rees CA, Pollack JR, Ross DT, Johnsen H, Akslen LA, et al: Molecular portraits of human breast tumours. Nature. 2000, 406: 747-752. 10.1038/35021093.CrossRefPubMed

Hu Z, Fan C, Oh DS, Marron JS, He X, Qaqish BF, Livasy C, Carey LA, Reynolds E, Dressler L, et al: The molecular portraits of breast tumors are conserved across microarray platforms. BMC Genomics. 2006, 7: 96-10.1186/1471-2164-7-96.CrossRefPubMedPubMedCentral

Sørlie T, Tibshirani R, Parker J, Hastie T, Marron JS, Nobel A, Deng S, Johnsen H, Pesich R, Geisler S, et al: Repeated observation of breast tumor subtypes in independent gene expression data sets. Proc Natl Acad Sci USA. 2003, 100: 8418-8423. 10.1073/pnas.0932692100.CrossRefPubMedPubMedCentral

Title: Are triple-negative tumours and basal-like breast cancer synonymous? Authors' response
Authors: Bas Kreike
Marc J van de Vijver
Publication date: 01-12-2007
Publisher: BioMed Central
Published in: Breast Cancer Research / Issue 6/2007
Electronic ISSN: 1465-542X
DOI: https://doi.org/10.1186/bcr1832

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