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01-05-2016 | Review Article

Application of Flow Cytometry in the Evaluation of Primary Immunodeficiencies

Authors: Thomas A. Fleisher, Manisha Madkaikar, Sergio D. Rosenzweig

Published in: Indian Journal of Pediatrics | Issue 5/2016

Abstract

Primary immunodeficiency disorders (PIDDs) are a heterogeneous group of inherited disorders of the immune system. Currently more than 250 different PIDDs with a known genetic defect have been recognized. The diagnosis of many of these disorders is supported strongly by a wide variety of flow cytometry applications. Flow cytometry offers a rapid and sensitive tool for diagnosis and classification of PIDDs. It is applicable in the initial workup and subsequent management of several primary immunodeficiency diseases. As our understanding of the pathogenesis and management of these diseases increases, the majority of these tests can be easily established in the diagnostic laboratory. Thus, the focus of this article is on the application of flow cytometry in the diagnosis and/or evaluation of PIDDs.

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Title: Application of Flow Cytometry in the Evaluation of Primary Immunodeficiencies
Authors: Thomas A. Fleisher
Manisha Madkaikar
Sergio D. Rosenzweig
Publication date: 01-05-2016
Publisher: Springer India
Published in: Indian Journal of Pediatrics / Issue 5/2016
Print ISSN: 0019-5456
Electronic ISSN: 0973-7693
DOI: https://doi.org/10.1007/s12098-015-2011-0

At a glance: The STEP trials

Springer Medicine

Application of Flow Cytometry in the Evaluation of Primary Immunodeficiencies

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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