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01-06-2016 | Editorial

Application of a Small Molecule Radiopharmaceutical Concept to Improve Kinetics

Author: Jae Min Jeong

Published in: Nuclear Medicine and Molecular Imaging | Issue 2/2016

Abstract

Recently, large molecules or nanoparticles are actively studied as radiopharmaceuticals. However, their kinetics is problematic because of a slow penetration through the capillaries and slow distribution to the target. To improve the kinetics, a two-step targeting method can be applied by using small molecules and very rapid copper-free click reaction. Although this method might have limitations such as internalization of the first targeted conjugate, it will provide high target-to-non-target ratio imaging of radiopharmaceuticals.

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Title: Application of a Small Molecule Radiopharmaceutical Concept to Improve Kinetics
Author: Jae Min Jeong
Publication date: 01-06-2016
Publisher: Springer Berlin Heidelberg
Published in: Nuclear Medicine and Molecular Imaging / Issue 2/2016
Print ISSN: 1869-3474
Electronic ISSN: 1869-3482
DOI: https://doi.org/10.1007/s13139-015-0369-6

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Application of a Small Molecule Radiopharmaceutical Concept to Improve Kinetics

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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