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Published in: Perioperative Medicine 1/2024

Open Access 01-12-2024 | Appendectomy | Research

Impact of preoperative factors and waiting time on post-appendectomy complications: a retrospective study

Authors: Shuo-Lun Lai, Chin-Hao Chang, Po-Chu Lee, Cheng-Maw Ho, Jin-Ming Wu, Hong-Shiee Lai, Been-Ren Lin

Published in: Perioperative Medicine | Issue 1/2024

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Abstract

Background

Several factors are associated with increased postoperative complications after appendectomies. However, few studies combined these potential factors for comprehensive prediction of surgical outcomes. Whether high-risk patients benefit from a shorter waiting time for surgery remains unclear. This study aimed to explore the impact of surgical waiting time and potential risk factors on postoperative complications.

Methods

A total of 1343 patients diagnosed with acute appendicitis requiring an emergent appendectomy were included from 2013 to 2018. The preoperative risk factors associated with postoperative complications were selected and the probability of postoperative complications was calculated by multivariate logistic regression model. Patients were divided into four groups based on the risk (high & low) and time to surgery (> 12 & ≤12 hours). The odds ratios for complications were evaluated between groups.

Results

The selected risk factors included age, neutrophil-lymphocyte ratio, systemic inflammatory response syndrome and abdominal pain duration. Compared with low-risk patients with time to surgery ≤12 hours, high-risk patients with time to surgery > 12 hours had significant increased overall postoperative complication rate (16.85% vs. 8.16%, p = 0.002) and a trend toward increased surgical site infection rate (10.99% vs. 6.46%, p = 0.058). When operated within 12 hours, there was no difference in outcomes between high- and low-risk patients. On the other hand, time to surgery > 12 hours did not increase complication rate in low-risk patients.

Conclusions

The surgical outcome may be affected by preoperative factors and time to surgery. It is suggested that high-risk patients receive appendectomy within 12 hours to avoid increased postoperative complications.
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Literature
Metadata
Title
Impact of preoperative factors and waiting time on post-appendectomy complications: a retrospective study
Authors
Shuo-Lun Lai
Chin-Hao Chang
Po-Chu Lee
Cheng-Maw Ho
Jin-Ming Wu
Hong-Shiee Lai
Been-Ren Lin
Publication date
01-12-2024
Publisher
BioMed Central
Published in
Perioperative Medicine / Issue 1/2024
Electronic ISSN: 2047-0525
DOI
https://doi.org/10.1186/s13741-024-00365-z

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