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Graefe's Archive for Clinical and Experimental Ophthalmology

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01-02-2017 | Pediatrics

Apgar score and reduced vision in children aged 3 to 6 years

Authors: Chen-Wei Pan, Deng-Juan Qian, Hui Zhu, Jia-Jia Yu, Hu Liu

Published in: Graefe's Archive for Clinical and Experimental Ophthalmology | Issue 2/2017

Abstract

Purpose

We aimed to examine the association between the 5-min Apgar score and reduced vision in children 3 to 6 years of age.

Methods

A total of 5834 preschool children aged 3 to 6 years participated in this school-based eye survey. Reduced vision was defined as unaided distance vision of 6/12 or worse in the better-seeing eye. The 5-min Apgar scores of the participants were retrieved from medical records.

Results

The overall prevalence of reduced vision in this population was 6.63 % (95 % confidence interval [CI] 5.99–7.27). In multivariate analysis, the presence of reduced vision was associated with a low 5-min Apgar score at birth (<7 vs. 7–10; odds ratio [OR] = 1.66, 95 % CI 1.48–3.05) after adjusting for age, gender, parental history of myopia, maternal age, gestational age, and birth weight. In addition, both myopia and amblyopia were associated with Apgar scores of less than 7 in multivariate analyses.

Conclusions

Children with 5-min Apgar scores of less than 7 were more likely to have reduced vision at the age of 3 to 6 years.

Robaei D, Rose K, Ojaimi E, Kifley A, Huynh S, Mitchell P (2005) Visual acuity and the causes of visual loss in a population-based sample of 6-year-old Australian children. Ophthalmology 112(7):1275–1282. doi:10.1016/j.ophtha.2005.01.052 CrossRefPubMed

Sun HP, Li A, Xu Y, Pan CW (2015) Secular trends of reduced visual acuity from 1985 to 2010 and disease burden projection for 2020 and 2030 among primary and secondary school students in China. JAMA Ophthalmol 133(3):262–268. doi:10.1001/jamaophthalmol.2014.4899 CrossRefPubMed

Dirani M, Zhou B, Hornbeak D, Chang BC, Gazzard G, Chia A, Ling Y, Selvaraj P, Young TL, Varma R, Wong TY, Saw SM (2010) Prevalence and causes of decreased visual acuity in Singaporean Chinese preschoolers. Br J Ophthalmol 94(12):1561–1565. doi:10.1136/bjo.2009.173104 CrossRefPubMed

Wong HB, Machin D, Tan SB, Wong TY, Saw SM (2009) Visual impairment and its impact on health-related quality of life in adolescents. Am J Ophthalmol 147(3):505–511 e501. doi:10.1016/j.ajo.2008.09.025 CrossRefPubMed

Mueller NT, Whyatt R, Hoepner L, Oberfield S, Dominguez-Bello MG, Widen EM, Hassoun A, Perera F, Rundle A (2015) Prenatal exposure to antibiotics, cesarean section and risk of childhood obesity. Int J Obes (Lond) 39(4):665–670. doi:10.1038/ijo.2014.180 CrossRef

Nielsen JH, Haase TN, Jaksch C, Nalla A, Sostrup B, Nalla AA, Larsen L, Rasmussen M, Dalgaard LT, Gaarn LW, Thams P, Kofod H, Billestrup N (2014) Impact of fetal and neonatal environment on beta cell function and development of diabetes. Acta Obstet Gynecol Scand 93(11):1109–1122. doi:10.1111/aogs.12504 CrossRefPubMed

Yim HE, Yoo KH (2014) Early life obesity and chronic kidney disease in later life. Pediatr Nephrol. doi:10.1007/s00467-014-2922-4

Sevelsted A, Bisgaard H (2012) Neonatal size in term children is associated with asthma at age 7, but not with atopic dermatitis or allergic sensitization. Allergy 67(5):670–675. doi:10.1111/j.1398-9995.2012.02805.x CrossRefPubMed

Bird A (2007) Perceptions of epigenetics. Nature 447(7143):396–398. doi:10.1038/nature05913 CrossRefPubMed

10.

Iliodromiti S, Mackay DF, Smith GC, Pell JP, Nelson SM (2014) Apgar score and the risk of cause-specific infant mortality: a population-based cohort study. Lancet 384(9956):1749–1755. doi:10.1016/S0140-6736(14)61135-1 CrossRefPubMed

11.

Pan CW, Chen X, Gong Y, Yu J, Ding H, Bai J, Chen J, Zhu H, Fu Z, Liu H (2015) Prevalence and causes of reduced visual acuity among children aged three to six years in a metropolis in China. Ophthalmic Physiol Opt. doi:10.1111/opo.12249

12.

Apgar V (1953) A proposal for a new method of evaluation of the newborn infant. Curr Res Anesth Analg 32(4):260–267PubMed

13.

Casey BM, McIntire DD, Leveno KJ (2001) The continuing value of the Apgar score for the assessment of newborn infants. N Engl J Med 344(7):467–471. doi:10.1056/NEJM200102153440701 CrossRefPubMed

14.

Ehrenstein V (2009) Association of Apgar scores with death and neurologic disability. Clin Epidemiol 1:45–53CrossRefPubMedPubMedCentral

15.

Friedman DS, Repka MX, Katz J, Giordano L, Ibironke J, Hawes P, Burkom D, Tielsch JM (2008) Prevalence of decreased visual acuity among preschool-aged children in an American urban population: the Baltimore Pediatric Eye Disease Study, methods, and results. Ophthalmology 115(10):1786–1795. doi:10.1016/j.ophtha.2008.04.006, 1795 e1781-1784CrossRefPubMedPubMedCentral

16.

Multi-Ethnic Pediatric Eye Disease Study G (2009) Prevalence and causes of visual impairment in African-American and Hispanic preschool children: the multi-ethnic pediatric eye disease study. Ophthalmology 116(10):1990–2000 e1991. doi:10.1016/j.ophtha.2009.03.027 CrossRef

17.

Tarczy-Hornoch K, Cotter SA, Borchert M, McKean-Cowdin R, Lin J, Wen G, Kim J, Varma R, Multi-Ethnic Pediatric Eye Disease Study G (2013) Prevalence and causes of visual impairment in Asian and non-Hispanic white preschool children: Multi-ethnic Pediatric Eye Disease Study. Ophthalmology 120(6):1220–1226. doi:10.1016/j.ophtha.2012.12.029 CrossRefPubMedPubMedCentral

18.

Chen X, Fu Z, Yu J, Ding H, Bai J, Chen J, Gong Y, Zhu H, Yu R, Liu H (2016) Prevalence of amblyopia and strabismus in Eastern China: results from screening of preschool children aged 36–72 months. Br J Ophthalmol 100(4):515–519. doi:10.1136/bjophthalmol-2015-306999 CrossRefPubMed

Title: Apgar score and reduced vision in children aged 3 to 6 years
Authors: Chen-Wei Pan
Deng-Juan Qian
Hui Zhu
Jia-Jia Yu
Hu Liu
Publication date: 01-02-2017
Publisher: Springer Berlin Heidelberg
Published in: Graefe's Archive for Clinical and Experimental Ophthalmology / Issue 2/2017
Print ISSN: 0721-832X
Electronic ISSN: 1435-702X
DOI: https://doi.org/10.1007/s00417-016-3506-8

At a glance: The STEP trials

Springer Medicine

Apgar score and reduced vision in children aged 3 to 6 years

Abstract

Purpose

Methods

Results

Conclusions

At a glance: The STEP trials

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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