Skip to main content
Top
Published in: BMC Infectious Diseases 1/2022

Open Access 01-12-2022 | Aortic Aneurysm | Case report

Brucellosis relapse causing thoracic aortic ulcers and aneurysm formation: a case report

Authors: Shuai Li, Qiang Wang

Published in: BMC Infectious Diseases | Issue 1/2022

Login to get access

Abstract

Background

Brucellosis is an infectious disease caused by Brucella spp, which can involve the cardiovascular, digestive, and respiratory systems. Cardiovascular involvement is a rare occurrence, it has an extremely high mortality rate.

Case presentation

A 67-year-old Chinese man presented with thoracic aortic multiple ulcers and partial aneurysm formation that caused symptoms of left waist and left buttock pain. The man was admitted to our hospital due to abdominal aorta pseudoaneurysms 5 years ago. The diagnosis was made by thoracic computed tomography angiography (CTA), previous history, and positive culture of Brucella, and the patient was successfully treated by thoracic aortic covered stent-graft implantation and specific medical treatment.

Conclusions

People who have a history of contact with cattle and sheep, should beware of the possibility of Brucella infection. If chest and abdominal pain occur, timely medical treatment is recommended, aortic aneurysm, the disease with a high risk of death, can be identified or excluded by CTA. Early treatment and prevention of disease progression are more beneficial to patients.
Literature
1.
go back to reference Colmenero JD, Reguera JM, Martos F, Sánchez-De-Mora D, Delgado M, Causse M, Martín-Farfán A, C J. Complications associated with Brucella melitensis infection: a study of 530 cases. Medicine. 1996;75(4):195–211.CrossRef Colmenero JD, Reguera JM, Martos F, Sánchez-De-Mora D, Delgado M, Causse M, Martín-Farfán A, C J. Complications associated with Brucella melitensis infection: a study of 530 cases. Medicine. 1996;75(4):195–211.CrossRef
2.
go back to reference Cakalagaoglu C, Keser N. Brucella-mediated prosthetic valve endocarditis with brachial artery mycotic aneurysm. J Heart Valve Dis. 1999;8(5):586–90.PubMed Cakalagaoglu C, Keser N. Brucella-mediated prosthetic valve endocarditis with brachial artery mycotic aneurysm. J Heart Valve Dis. 1999;8(5):586–90.PubMed
3.
go back to reference Reguera JM, Alarcón A, Miralles F, Pachón J, Juárez C. Brucella endocarditis: clinical, diagnostic, and therapeutic approach. Eur J Clin Microbiol Infect Dis. 2003;22(11):647–50.CrossRef Reguera JM, Alarcón A, Miralles F, Pachón J, Juárez C. Brucella endocarditis: clinical, diagnostic, and therapeutic approach. Eur J Clin Microbiol Infect Dis. 2003;22(11):647–50.CrossRef
4.
go back to reference Pappas G, Akritidis N, Bosilkovski M. Brucellosis. Engl J med. 2005;352(22):2325–36.CrossRef Pappas G, Akritidis N, Bosilkovski M. Brucellosis. Engl J med. 2005;352(22):2325–36.CrossRef
5.
go back to reference Wen-hong Z, Zhang Y-X. Brucella diagnosis and treatment expert consensus. Chin J Infect Dis. 2017;35(12):705–10. Wen-hong Z, Zhang Y-X. Brucella diagnosis and treatment expert consensus. Chin J Infect Dis. 2017;35(12):705–10.
6.
go back to reference Kakkos SK, Papadoulas S, Lampropoulos G, Marangos M, Kalogeropoulou C, IA T. Aorto-iliac aneurysm infected by Brucella: distinctive presentation patterns of a rare entity. Vascular. 2013;21(5):307–15.CrossRef Kakkos SK, Papadoulas S, Lampropoulos G, Marangos M, Kalogeropoulou C, IA T. Aorto-iliac aneurysm infected by Brucella: distinctive presentation patterns of a rare entity. Vascular. 2013;21(5):307–15.CrossRef
7.
go back to reference Wang S, Wang Q, Liu H, Sun S, Sun X, Zhang Y, Wang Z. Endovascular treatment of thoracic aortic pseudoaneurysm due to brucellosis: a rare case report. BMC Infect Dis. 2017;17(1):387.CrossRef Wang S, Wang Q, Liu H, Sun S, Sun X, Zhang Y, Wang Z. Endovascular treatment of thoracic aortic pseudoaneurysm due to brucellosis: a rare case report. BMC Infect Dis. 2017;17(1):387.CrossRef
8.
go back to reference Alsheef M, Alsaleh S, Alanezi N, Bakhsh N, AlDosary R, AlSharif L, Mian A, Ahsan A. Descending thoracic aortic aneurysm due to brucella melitensis. Hindawi. 2019;2019:4939452. Alsheef M, Alsaleh S, Alanezi N, Bakhsh N, AlDosary R, AlSharif L, Mian A, Ahsan A. Descending thoracic aortic aneurysm due to brucella melitensis. Hindawi. 2019;2019:4939452.
9.
go back to reference Zhang T, Ji D. Endovascular treatment of Brucella-infected abdominal aortic aneurysm: A case report. Medicine. 2017;96(42):e7666.CrossRef Zhang T, Ji D. Endovascular treatment of Brucella-infected abdominal aortic aneurysm: A case report. Medicine. 2017;96(42):e7666.CrossRef
10.
go back to reference Alhaizaey A, Alassiri M, Alghamdi M. Mycotic aortic aneurysm due to brucellosis. J Vasc Surg Cases Innov Tech. 2016;2(2):50–2.CrossRef Alhaizaey A, Alassiri M, Alghamdi M. Mycotic aortic aneurysm due to brucellosis. J Vasc Surg Cases Innov Tech. 2016;2(2):50–2.CrossRef
11.
go back to reference Fuchs I, Taylor J, Malev A. Definitive endovascular repair of a brucellar descending thoracic aortic aneurysm. Isr Med Assoc J. 2017;19(5):325–7.PubMed Fuchs I, Taylor J, Malev A. Definitive endovascular repair of a brucellar descending thoracic aortic aneurysm. Isr Med Assoc J. 2017;19(5):325–7.PubMed
12.
go back to reference Li H-L, Chan YC, Cui D-Z, Li N, Cheng SW. Successful endovascular aneurysm repair for brucella mycotic aneurysm acquired from ingestion of sheep placenta. Ann Vasc Surg. 2019;57:274–274.CrossRef Li H-L, Chan YC, Cui D-Z, Li N, Cheng SW. Successful endovascular aneurysm repair for brucella mycotic aneurysm acquired from ingestion of sheep placenta. Ann Vasc Surg. 2019;57:274–274.CrossRef
13.
go back to reference Amirghofran AA, Karimi A, Emaminia A, Sharifkazemi MB. Brucellosis relapse causing prosthetic valve endocarditis and aortic root infective pseudoaneurysm. Ann Thorac Surg. 2011;92(4):e77-9.CrossRef Amirghofran AA, Karimi A, Emaminia A, Sharifkazemi MB. Brucellosis relapse causing prosthetic valve endocarditis and aortic root infective pseudoaneurysm. Ann Thorac Surg. 2011;92(4):e77-9.CrossRef
14.
go back to reference Cascio A, De Caridi G, Lentini S, Benedetto F, Stilo F, Passari G, Iaria C, Spinelli F. Involvement of the aorta in brucellosis: the forgotten, life-threatening complication. A systematic review. Vector Borne Zoonotic Dis. 2012;12(10):827–40.CrossRef Cascio A, De Caridi G, Lentini S, Benedetto F, Stilo F, Passari G, Iaria C, Spinelli F. Involvement of the aorta in brucellosis: the forgotten, life-threatening complication. A systematic review. Vector Borne Zoonotic Dis. 2012;12(10):827–40.CrossRef
15.
go back to reference Ferrero MC, Bregante J, Delpino MV, Barrionuevo P, Fossati CA, Giambartolomei GH, PC B. Proinflammatory response of human endothelial cells to Brucella infection. Microbes Infect. 2011;13(10):852–61.CrossRef Ferrero MC, Bregante J, Delpino MV, Barrionuevo P, Fossati CA, Giambartolomei GH, PC B. Proinflammatory response of human endothelial cells to Brucella infection. Microbes Infect. 2011;13(10):852–61.CrossRef
16.
go back to reference Buzgan T, Karahocagil MK, Irmak H, Baran AI, Karsen H, Evirgen O, Akdeniz H. Clinical manifestations and complications in 1028 cases of brucellosis: a retrospective evaluation and review of the literature. Int J Infect Dis. 2010;14(6):e469-78.CrossRef Buzgan T, Karahocagil MK, Irmak H, Baran AI, Karsen H, Evirgen O, Akdeniz H. Clinical manifestations and complications in 1028 cases of brucellosis: a retrospective evaluation and review of the literature. Int J Infect Dis. 2010;14(6):e469-78.CrossRef
Metadata
Title
Brucellosis relapse causing thoracic aortic ulcers and aneurysm formation: a case report
Authors
Shuai Li
Qiang Wang
Publication date
01-12-2022
Publisher
BioMed Central
Published in
BMC Infectious Diseases / Issue 1/2022
Electronic ISSN: 1471-2334
DOI
https://doi.org/10.1186/s12879-021-07005-7

Other articles of this Issue 1/2022

BMC Infectious Diseases 1/2022 Go to the issue
Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.