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Child and Adolescent Psychiatry and Mental Health

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Open Access 01-12-2023 | Anxiety | Research

Randomized controlled trial for selective preventive transdiagnostic intervention for adolescents at risk for emotional disorders

Authors: Manuel Vivas-Fernandez, Luis-Joaquin Garcia-Lopez, Jose A. Piqueras, Jose-Antonio Muela-Martinez, Josefa Canals-Sans, Lourdes Espinosa-Fernandez, David Jimenez-Vazquez, Maria del Mar Diaz-Castela, Paula Morales-Hidalgo, Maria Rivera, Jill Ehrenreich-May

Published in: Child and Adolescent Psychiatry and Mental Health | Issue 1/2023

Abstract

Significant evidence does exist on the effectiveness of transdiagnostic interventions to improve emotional problems in clinical populations, and their application as universal and indicated prevention programs. However, no randomized controlled trials (RCT) studying selective transdiagnostic prevention intervention have been published. This is the first known RCT to evaluate the efficacy/effectiveness of an evidence-based selective prevention transdiagnostic program for emotional problems in adolescents. The impact of three different interventions was evaluated: (1) PROCARE (Preventive transdiagnostic intervention for Adolescents at Risk for Emotional disorders), which is a group-based, abbreviated version of the Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Adolescents (UP-A), along with adding a booster session to reduce risk of onset of anxiety and depression, (2) PROCARE + , which includes the PROCARE protocol along with personalized add-on modules tailored to match adolescents’ risk factors, and (3) an active control condition (ACC) based on emotional psychoeducation. In total, 208 adolescents (48.5% girls) evidencing high risk and low protective factors were randomized and allocated to PROCARE, PROCARE + or ACC. Data from 153 adolescents who completed all assessments in the different phases of the study were analyzed. Self- and parent-reported measures were taken at baseline, as well as after the intervention, a 6 month follow-up was carried out, together with a 1 month follow-up after the booster session. Differences between conditions were significant on most of the outcome measures, with superior effect sizes for PROCARE + in the short and long term. Interventions were acceptable in terms of acceptability, with good satisfaction rates. Tailored targeted selective transdiagnostic interventions focused on mitigating risk factors and promoting protective factors in vulnerable adolescents are promising.

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Title: Randomized controlled trial for selective preventive transdiagnostic intervention for adolescents at risk for emotional disorders
Authors: Manuel Vivas-Fernandez
Luis-Joaquin Garcia-Lopez
Jose A. Piqueras
Jose-Antonio Muela-Martinez
Josefa Canals-Sans
Lourdes Espinosa-Fernandez
David Jimenez-Vazquez
Maria del Mar Diaz-Castela
Paula Morales-Hidalgo
Maria Rivera
Jill Ehrenreich-May
Publication date: 01-12-2023
Publisher: BioMed Central
Keywords: Anxiety
Mood Disorders
Affective Disorder
Published in: Child and Adolescent Psychiatry and Mental Health / Issue 1/2023
Electronic ISSN: 1753-2000
DOI: https://doi.org/10.1186/s13034-023-00616-9

2024 ASCO Annual Meeting

Springer Medicine

Randomized controlled trial for selective preventive transdiagnostic intervention for adolescents at risk for emotional disorders

Abstract

2024 ASCO Annual Meeting

Springer Medicine

Abstract

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