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Published in: Journal of Gastrointestinal Surgery 6/2019

01-06-2019 | Antireflux Surgery | 2018 SSAT Plenary Presentation

Does Treatment of the Hiatus Influence the Outcomes of Magnetic Sphincter Augmentation for Chronic GERD?

Authors: Matías Mihura Irribarra, Sandra Blitz, Candice L. Wilshire, Anee Sophia Jackson, Alexander S. Farivar, Ralph W. Aye, Christy M. Dunst, Brian E. Louie

Published in: Journal of Gastrointestinal Surgery | Issue 6/2019

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Abstract

Background

Hiatal dissection, restoration of esophageal intra-abdominal length, and crural closure are key components of successful antireflux surgery. The necessity of addressing these components prior to magnetic sphincter augmentation (MSA) has been questioned. We aimed to compare outcomes of MSA between groups with differing hiatal dissection and closure.

Methods

We retrospectively reviewed 259 patients who underwent MSA from 2009 to 2017. Patients were categorized based on hiatal treatment: minimal dissection (MD), crural closure (CC), formal crural repair (FC), and extensive dissection without closure (ED). The primary outcome was normalization of postoperative DeMeester score (≤ 14.72). Univariable and multivariable logistic regression was used to assess which preoperative predictors achieved normalization.

Results

Of the 197 patients, MD was used in 81 (41%); FC in 42 (22%); CC in 40 (20%); and ED in 34 (17%). Normalization occurred in 104 (53%) patients, with MD achieving normalization in 45/81 (56%); FC in 25/42 (60%); CC in 21/40 (53%); and ED 13/34 (38%). After regression, FC was most likely to normalize acid exposure. The presence of a hiatal hernia, defective LES, and higher preoperative DeMeester score were less likely to achieve normalization.

Conclusions

Hiatal dissection with restoration of esophageal length and crural closure during MSA increases the likelihood of normalizing acid exposure.
Footnotes
1
The 12-bead device is no longer available.
 
Literature
1.
go back to reference Schneider AM, Louie BE. Anatomy of the Reflux Barrier in Health, Disease, and Recinstruction. In: Aye RW, Hunter JG, editors. Fundoplication Surgery. Switzerland: Springer International Publishing; 2016. p. 1–17. Schneider AM, Louie BE. Anatomy of the Reflux Barrier in Health, Disease, and Recinstruction. In: Aye RW, Hunter JG, editors. Fundoplication Surgery. Switzerland: Springer International Publishing; 2016. p. 1–17.
2.
go back to reference Louie BE, Kapur S, Blitz M, Farivar AS, Vallières E, Aye RW. Length and Pressure of the Reconstructed Lower Esophageal Sphincter is Determined by Both Crural Closure and Nissen Fundoplication. J Gastrointest Surg. 2013;17(2):236–43.CrossRefPubMed Louie BE, Kapur S, Blitz M, Farivar AS, Vallières E, Aye RW. Length and Pressure of the Reconstructed Lower Esophageal Sphincter is Determined by Both Crural Closure and Nissen Fundoplication. J Gastrointest Surg. 2013;17(2):236–43.CrossRefPubMed
3.
go back to reference Bonavina L, Saino GI, Bona D, Lipham J, Ganz RA, Dunn D, et al. Magnetic augmentation of the lower esophageal sphincter: Results of a feasibility clinical trial. J Gastrointest Surg. 2008;12(12):2133–40.CrossRefPubMed Bonavina L, Saino GI, Bona D, Lipham J, Ganz RA, Dunn D, et al. Magnetic augmentation of the lower esophageal sphincter: Results of a feasibility clinical trial. J Gastrointest Surg. 2008;12(12):2133–40.CrossRefPubMed
4.
go back to reference Warren HF, Brown LM, Mihura M, Farivar AS, Aye RW, Louie BE, et al. Factors influencing the outcome of magnetic sphincter augmentation for chronic gastroesophageal reflux disease. Surg Endosc. 2018; 32(1):405-412.CrossRefPubMed Warren HF, Brown LM, Mihura M, Farivar AS, Aye RW, Louie BE, et al. Factors influencing the outcome of magnetic sphincter augmentation for chronic gastroesophageal reflux disease. Surg Endosc. 2018; 32(1):405-412.CrossRefPubMed
5.
go back to reference Ganz RA, Peters JH, Horgan S, Bemelman WA, Dunst CM, Edmundowicz SA, et al. Esophageal sphincter device for gastroesophageal reflux disease. N Engl J Med. 2013;368(8):719–27.CrossRefPubMed Ganz RA, Peters JH, Horgan S, Bemelman WA, Dunst CM, Edmundowicz SA, et al. Esophageal sphincter device for gastroesophageal reflux disease. N Engl J Med. 2013;368(8):719–27.CrossRefPubMed
6.
go back to reference Velanovich V. The development of the GERD-HRQL symptom severity instrument. Dis Esophagus. 2007;20(2):130–4.CrossRefPubMed Velanovich V. The development of the GERD-HRQL symptom severity instrument. Dis Esophagus. 2007;20(2):130–4.CrossRefPubMed
7.
go back to reference Ayazi S, Hagen JA, Zehetner J, Ross O, Wu C, Oezcelik A, et al. The value of high-resolution manometry in the assessment of the resting characteristics of the lower esophageal sphincter. J Gastrointest Surg. 2009;13(12):2113–20.CrossRefPubMed Ayazi S, Hagen JA, Zehetner J, Ross O, Wu C, Oezcelik A, et al. The value of high-resolution manometry in the assessment of the resting characteristics of the lower esophageal sphincter. J Gastrointest Surg. 2009;13(12):2113–20.CrossRefPubMed
8.
go back to reference Campos G, Peters JH, DeMeester TR, Obert S, Crookes PF, Tan S, et al. Multivariate analysis of factors predicting outcome after laparoscopic Nissen fundoplication. J Gastrointest Surg. 1998;4(6):650. Campos G, Peters JH, DeMeester TR, Obert S, Crookes PF, Tan S, et al. Multivariate analysis of factors predicting outcome after laparoscopic Nissen fundoplication. J Gastrointest Surg. 1998;4(6):650.
9.
go back to reference Warren HF, Louie BE, Farivar AS, Wilshire C, Aye RW. Manometric Changes to the Lower Esophageal Sphincter after Magnetic Sphincter Augmentation in Patients with Chronic Gastroesophageal Reflux Disease. Ann Surg. 2017;266(1):99–104.CrossRefPubMed Warren HF, Louie BE, Farivar AS, Wilshire C, Aye RW. Manometric Changes to the Lower Esophageal Sphincter after Magnetic Sphincter Augmentation in Patients with Chronic Gastroesophageal Reflux Disease. Ann Surg. 2017;266(1):99–104.CrossRefPubMed
10.
go back to reference Kahrilas PJ, Lin S, Manka M, Shi G, Joehl RJ. Esophagogastric junction pressure topography after fundoplication. Surgery. 2000;127(2):200–8.CrossRefPubMed Kahrilas PJ, Lin S, Manka M, Shi G, Joehl RJ. Esophagogastric junction pressure topography after fundoplication. Surgery. 2000;127(2):200–8.CrossRefPubMed
11.
go back to reference Schwameis K, Nikolic M, Castellano DGM, Steindl A, Macheck S, Riegler M, et al. Crural closure improves outcomes of magnetic sphincter augmentation in GERD patients with hiatal hernia. Sci Rep. 2018;8(1):1–7.CrossRef Schwameis K, Nikolic M, Castellano DGM, Steindl A, Macheck S, Riegler M, et al. Crural closure improves outcomes of magnetic sphincter augmentation in GERD patients with hiatal hernia. Sci Rep. 2018;8(1):1–7.CrossRef
12.
go back to reference James M Tatum, MD, Evan Alicuben, MD, Nikolai Bildzukewicz, MD, Kulmeet Sandhu, MD, Kameron Samakar, MD, Caitlin Houghton, MD, John L Lipham M. Minimal vs. Obligatory Dissection of the Diaphragmatic Hiatus During Magnetic Sphincter Augmentation Surgery: An Intention to Treat Analysis. Surg Endosc [Internet]. 2018; Available from: https://doi.org/10.1007/s00464-018-6119-y James M Tatum, MD, Evan Alicuben, MD, Nikolai Bildzukewicz, MD, Kulmeet Sandhu, MD, Kameron Samakar, MD, Caitlin Houghton, MD, John L Lipham M. Minimal vs. Obligatory Dissection of the Diaphragmatic Hiatus During Magnetic Sphincter Augmentation Surgery: An Intention to Treat Analysis. Surg Endosc [Internet]. 2018; Available from: https://​doi.​org/​10.​1007/​s00464-018-6119-y
13.
go back to reference Bonavina L, Saino G, Bona D, Sironi A, Lazzari V. One hundred consecutive patients treated with magnetic sphincter augmentation for gastroesophageal reflux disease: 6 years of clinical experience from a single center. J Am Coll Surg. 2013;217(4):577–85.CrossRefPubMed Bonavina L, Saino G, Bona D, Sironi A, Lazzari V. One hundred consecutive patients treated with magnetic sphincter augmentation for gastroesophageal reflux disease: 6 years of clinical experience from a single center. J Am Coll Surg. 2013;217(4):577–85.CrossRefPubMed
15.
go back to reference Lord RVN, Demeester SR, Peters JH, Hagen JA, Elyssnia D, Sheth CT, et al. Hiatal Hernia, lower esophageal sphincter incompetence, and effectiveness of nissen fundoplication in the spectrum of gastroesophageal reflux disease. J Gastrointest Surg. 2009;13(4):602–10.CrossRefPubMed Lord RVN, Demeester SR, Peters JH, Hagen JA, Elyssnia D, Sheth CT, et al. Hiatal Hernia, lower esophageal sphincter incompetence, and effectiveness of nissen fundoplication in the spectrum of gastroesophageal reflux disease. J Gastrointest Surg. 2009;13(4):602–10.CrossRefPubMed
16.
go back to reference Buckley FP, Bell RCW, Freeman K, Doggett S, Heidrick R. Favorable results from a prospective evaluation of 200 patients with large hiatal hernias undergoing LINX magnetic sphincter augmentation. Surg Endosc Other Interv Tech. 2018;32(4):1762–8.CrossRef Buckley FP, Bell RCW, Freeman K, Doggett S, Heidrick R. Favorable results from a prospective evaluation of 200 patients with large hiatal hernias undergoing LINX magnetic sphincter augmentation. Surg Endosc Other Interv Tech. 2018;32(4):1762–8.CrossRef
17.
go back to reference Smith CD, Ganz RA, Lipham JC, Bell RC, Rattner DW. Lower Esophageal Sphincter Augmentation for Gastroesophageal Reflux Disease: The Safety of a Modern Implant. J Laparoendosc Adv Surg Tech. 2017;27(6):lap.2017.0025. Smith CD, Ganz RA, Lipham JC, Bell RC, Rattner DW. Lower Esophageal Sphincter Augmentation for Gastroesophageal Reflux Disease: The Safety of a Modern Implant. J Laparoendosc Adv Surg Tech. 2017;27(6):lap.2017.0025.
Metadata
Title
Does Treatment of the Hiatus Influence the Outcomes of Magnetic Sphincter Augmentation for Chronic GERD?
Authors
Matías Mihura Irribarra
Sandra Blitz
Candice L. Wilshire
Anee Sophia Jackson
Alexander S. Farivar
Ralph W. Aye
Christy M. Dunst
Brian E. Louie
Publication date
01-06-2019
Publisher
Springer US
Published in
Journal of Gastrointestinal Surgery / Issue 6/2019
Print ISSN: 1091-255X
Electronic ISSN: 1873-4626
DOI
https://doi.org/10.1007/s11605-019-04180-6

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