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Annals of Surgical Oncology
Published in: Annals of Surgical Oncology 3/2017

01-12-2017 | Colorectal Cancer

Antigen-Directed Cancer Surgery for Primary Colorectal Cancer: 15-Year Survival Analysis

Authors: J. P. Tiernan, MBChB, PhD, FRCS, D. G. Jayne, BSc, MB BCh, FRCS, MD

Published in: Annals of Surgical Oncology | Special Issue 3/2017

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Excerpt

We read with interest the article by Povoski et al. concerning the long-term follow-up of patients who had resections for colorectal cancer performed using antigen-directed surgery.1 The authors have been at the forefront of research into radioimmunoguided surgery (RIGS) for over 25 years and are to be congratulated on their work. This paper compared survival data for 93 patients who underwent antigen-directed surgery between 1992 and 1995 and found that those who had no detectable bound antibody remaining in the surgical field at the end of the procedure had a significant survival advantage over those who did. …
Literature
1.
Povoski S, et al. Antigen-directed cancer surgery for primary colorectal cancer: 15-year survival analysis. Ann. Surg. Oncol. 2012;19(1):131–8.CrossRefPubMed
2.
Listrom MB, et al. Immunoreactivity of tumor-associated glycoprotein (TAG-72) in normal, hyperplastic, and neoplastic colon. Human Pathol. 1989;20(10):994–1000.CrossRef
3.
Hohenberger W, et al. Standardized surgery for colonic cancer: complete mesocolic excision and central ligation—technical notes and outcome. Colorectal Dis. 2009;11(4):354–64.CrossRefPubMed
Metadata
Title
Antigen-Directed Cancer Surgery for Primary Colorectal Cancer: 15-Year Survival Analysis
Authors
J. P. Tiernan, MBChB, PhD, FRCS
D. G. Jayne, BSc, MB BCh, FRCS, MD
Publication date
01-12-2017
Publisher
Springer International Publishing
Published in
Annals of Surgical Oncology / Issue Special Issue 3/2017
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-017-6200-0

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