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BMC Neurology

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Open Access 01-12-2023 | Antiepileptic Drugs | Research article

EEG spectral power during REM sleep in patients with frontal brain tumor

Authors: Laura Victoria Ortega-Leonard, Yolanda del Río-Portilla

Published in: BMC Neurology | Issue 1/2023

Abstract

Background

The main objective of this research was to analyze the characteristics of electrical activity in the brain during REM (Rapid Eye Movements) sleep, by using an experimental model a pathology that affects the frontal lobes, such as brain tumors. In addition to determining the impact of variables such as the frontal area (dorsolateral, medial and orbital), laterality and size of the lesion; as well as the demographic and clinical characteristics of the patients evaluated.

Methods

By using polysomnographic recordings, 10 patients were evaluated. We obtained power spectra through a homemade program. For quantitative EEG (Electroencephalogram) (qEEG) analysis, the Fast Fourier Transform (FFT) algorithm was used to obtain the spectral power of each participant, channel, and frequency band.

Results

Sleep architecture and spectral power was found to be modified in patients compared to normative values. Other sociodemographic and clinical characteristics of the patients were also influenced, such as age range and antiepileptic drugs.

Conclusions

Brain tumors in the frontal lobe can modify the rhythmogenesis of REM sleep, possibly due to changes of brain plasticity as an effect of the pathology. In addition to this, through this study we were able to show the association between neuroanatomical and functional changes, on the characteristics of brain electrical activity in patients with frontal brain tumor. Finally, this qEEG analysis technique allows, on the one hand, to deepen the knowledge and relationship between psychophysiological processes and, on the other hand, to be able to guide therapeutic decisions.

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Title: EEG spectral power during REM sleep in patients with frontal brain tumor
Authors: Laura Victoria Ortega-Leonard
Yolanda del Río-Portilla
Publication date: 01-12-2023
Publisher: BioMed Central
Keywords: Antiepileptic Drugs
Brain Tumor
Antiepileptic Drugs
Published in: BMC Neurology / Issue 1/2023
Electronic ISSN: 1471-2377
DOI: https://doi.org/10.1186/s12883-023-03243-1

Keynote webinar | Spotlight on medication adherence

Springer Medicine

EEG spectral power during REM sleep in patients with frontal brain tumor

Abstract

Background

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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