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Skeletal Radiology
Published in: Skeletal Radiology 9/2012

01-09-2012 | Perspective

Ankylosing Spondylitis – the changing role of imaging

Authors: Zoe Ash, Helena Marzo-Ortega

Published in: Skeletal Radiology | Issue 9/2012

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Excerpt

Ankylosing spondylitis (AS) is the disease prototype within a heterogeneous group of inflammatory arthritides known collectively as the seronegative spondyloarthropathies (SpA). The other subtypes as originally described by Moll and Wright are psoriatic arthritis, reactive arthritis and inflammatory bowel disease associated arthritis. The pathogenic hallmark of these diseases is inflammation at the entheses; the sites of attachment of ligament, fascia or tendon insertions into bone. This process affects primarily the axial skeleton, including the spine and sacroiliac joints. Extra-articular features of the disease can include uveitis, aortitis and inflammatory bowel disease. In the majority of cases AS affects individuals in their early twenties and thirties, causing long term pain and disability and leading to work instability and decreased quality of life. Early mortality has been reported, associated mainly with an increased risk of cardiovascular morbidity. …
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Metadata
Title
Ankylosing Spondylitis – the changing role of imaging
Authors
Zoe Ash
Helena Marzo-Ortega
Publication date
01-09-2012
Publisher
Springer-Verlag
Published in
Skeletal Radiology / Issue 9/2012
Print ISSN: 0364-2348
Electronic ISSN: 1432-2161
DOI
https://doi.org/10.1007/s00256-012-1466-6

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