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01-12-2024 | Aneurysm | Research

Dual Layer vs Single Layer Woven EndoBridge Device in the Treatment of Intracranial Aneurysms: A Propensity Score-Matched Analysis

Authors: Adam A. Dmytriw, Hamza Salim, Basel Musmar, Assala Aslan, Nicole M. Cancelliere, Rachel M. McLellan, Oktay Algin, Sherief Ghozy, Mahmoud Dibas, Sovann V. Lay, Adrien Guenego, Leonardo Renieri, Joseph Carnevale, Guillaume Saliou, Panagiotis Mastorakos, Kareem El Naamani, Eimad Shotar, Kevin Premat, Markus Möhlenbruch, Michael Kral, Omer Doron, Charlotte Chung, Mohamed M. Salem, Ivan Lylyk, Paul M. Foreman, Jay A. Vachhani, Hamza Shaikh, Vedran Župančić, Muhammad U. Hafeez, Joshua Catapano, Muhammad Waqas, Vincent M. Tutino, Mohamed K. Ibrahim, Marwa A. Mohammed, Cetin Imamoglu, Ahmet Bayrak, James D. Rabinov, Yifan Ren, Clemens M. Schirmer, Mariangela Piano, Anna L. Kühn, Caterina Michelozzi, Stéphanie Elens, Robert M. Starke, Ameer E. Hassan, Mark Ogilvie, Peter Sporns, Jesse Jones, Waleed Brinjikji, Marie T. Nawka, Marios Psychogios, Christian Ulfert, Jose Danilo Bengzon Diestro, Bryan Pukenas, Jan-Karl Burkhardt, Thien Huynh, Juan Carlos Martinez-Gutierrez, Muhammed Amir Essibayi, Sunil A. Sheth, Gary Spiegel, Rabih Tawk, Boris Lubicz, Pietro Panni, Ajit S. Puri, Guglielmo Pero, Erez Nossek, Eytan Raz, Monika Killer-Oberfalzer, Christoph J. Griessenauer, Hamed Asadi, Adnan Siddiqui, Allan L. Brook, David Altschul, Andrew F. Ducruet, Felipe C. Albuquerque, Robert W. Regenhardt, Christopher J. Stapleton, Peter Kan, Vladimir Kalousek, Pedro Lylyk, Srikanth Boddu, Jared Knopman, Mohammad A. Aziz-Sultan, Stavropoula I. Tjoumakaris, Frédéric Clarençon, Nicola Limbucci, Hugo H. Cuellar-Saenz, Pascal M. Jabbour, Vitor Mendes Pereira, Aman B. Patel, Nimer Adeeb

Published in: Neurosurgical Review | Issue 1/2024

Abstract

Background

The Woven EndoBridge (WEB) devices have been used for treating wide neck bifurcation aneurysms (WNBAs) with several generational enhancements to improve clinical outcomes. The original device dual-layer (WEB DL) was replaced by a single-layer (WEB SL) device in 2013. This study aimed to compare the effectiveness and safety of these devices in managing intracranial aneurysms.

Methods

A multicenter cohort study was conducted, and data from 1,289 patients with intracranial aneurysms treated with either the WEB SL or WEB DL devices were retrospectively analyzed. Propensity score matching was utilized to balance the baseline characteristics between the two groups. Outcomes assessed included immediate occlusion rate, complete occlusion at last follow-up, retreatment rate, device compaction, and aneurysmal rupture.

Results

Before propensity score matching, patients treated with the WEB SL had a significantly higher rate of complete occlusion at the last follow-up and a lower rate of retreatment. After matching, there was no significant difference in immediate occlusion rate, retreatment rate, or device compaction between the WEB SL and DL groups. However, the SL group maintained a higher rate of complete occlusion at the final follow-up. Regression analysis showed that SL was associated with higher rates of complete occlusion (OR: 0.19; CI: 0.04 to 0.8, p = 0.029) and lower rates of retreatment (OR: 0.12; CI: 0 to 4.12, p = 0.23).

Conclusion

The WEB SL and DL devices demonstrated similar performances in immediate occlusion rates and retreatment requirements for intracranial aneurysms. The SL device showed a higher rate of complete occlusion at the final follow-up.

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Title: Dual Layer vs Single Layer Woven EndoBridge Device in the Treatment of Intracranial Aneurysms: A Propensity Score-Matched Analysis
Authors: Adam A. Dmytriw
Hamza Salim
Basel Musmar
Assala Aslan
Nicole M. Cancelliere
Rachel M. McLellan
Oktay Algin
Sherief Ghozy
Mahmoud Dibas
Sovann V. Lay
Adrien Guenego
Leonardo Renieri
Joseph Carnevale
Guillaume Saliou
Panagiotis Mastorakos
Kareem El Naamani
Eimad Shotar
Kevin Premat
Markus Möhlenbruch
Michael Kral
Omer Doron
Charlotte Chung
Mohamed M. Salem
Ivan Lylyk
Paul M. Foreman
Jay A. Vachhani
Hamza Shaikh
Vedran Župančić
Muhammad U. Hafeez
Joshua Catapano
Muhammad Waqas
Vincent M. Tutino
Mohamed K. Ibrahim
Marwa A. Mohammed
Cetin Imamoglu
Ahmet Bayrak
James D. Rabinov
Yifan Ren
Clemens M. Schirmer
Mariangela Piano
Anna L. Kühn
Caterina Michelozzi
Stéphanie Elens
Robert M. Starke
Ameer E. Hassan
Mark Ogilvie
Peter Sporns
Jesse Jones
Waleed Brinjikji
Marie T. Nawka
Marios Psychogios
Christian Ulfert
Jose Danilo Bengzon Diestro
Bryan Pukenas
Jan-Karl Burkhardt
Thien Huynh
Juan Carlos Martinez-Gutierrez
Muhammed Amir Essibayi
Sunil A. Sheth
Gary Spiegel
Rabih Tawk
Boris Lubicz
Pietro Panni
Ajit S. Puri
Guglielmo Pero
Erez Nossek
Eytan Raz
Monika Killer-Oberfalzer
Christoph J. Griessenauer
Hamed Asadi
Adnan Siddiqui
Allan L. Brook
David Altschul
Andrew F. Ducruet
Felipe C. Albuquerque
Robert W. Regenhardt
Christopher J. Stapleton
Peter Kan
Vladimir Kalousek
Pedro Lylyk
Srikanth Boddu
Jared Knopman
Mohammad A. Aziz-Sultan
Stavropoula I. Tjoumakaris
Frédéric Clarençon
Nicola Limbucci
Hugo H. Cuellar-Saenz
Pascal M. Jabbour
Vitor Mendes Pereira
Aman B. Patel
Nimer Adeeb
Publication date: 01-12-2024
Publisher: Springer Berlin Heidelberg
Keywords: Aneurysm
Aneurysm
Intracranial Aneurysm
Published in: Neurosurgical Review / Issue 1/2024
Print ISSN: 0344-5607
Electronic ISSN: 1437-2320
DOI: https://doi.org/10.1007/s10143-024-02341-z

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Dual Layer vs Single Layer Woven EndoBridge Device in the Treatment of Intracranial Aneurysms: A Propensity Score-Matched Analysis

Abstract

Background

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusion

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