Adrenal Incidentaloma Camouflaging an Ovarian Leydig Cell Tumour: A Look Beneath the Surface

Excerpt

Hyperandrogenism is one of the most common endocrine disorder affecting around 7% of the women in their reproductive years [1]. Clinical presentation ranges from acne, hirsutism, menstrual irregularities to frank virilization. Congenital adrenal hyperplasia, ovarian hyperthecosis and androgen-secreting neoplasms are few disorders, which can lead to virilization. Androgen-secreting tumours are the least common cause of hyperandrogenism and may originate from either adrenals or ovaries [1]. Androgen-secreting leydig cell tumour in an ovary is very rare [2]. Small size of such tumours make it difficult to diagnose them by routine imaging procedures. Presence of both adrenal and ovarian tumours in a female with androgen excess is a condition which is diagnostically very challenging. Here, we report our experience in diagnosis and management of one such case. …