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Published in: Basic Research in Cardiology 4/2016

01-07-2016 | Invited Editorial

Anaesthetics and remote ischaemic preconditioning: do not stop the music, despite a (yet) unhappy marriage

Author: Jürgen Peters

Published in: Basic Research in Cardiology | Issue 4/2016

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Excerpt

Remote ischaemic preconditiong (RIPC), at least in the context of cardioprotection during heart surgery, has arrived at an apparent deadlock. …
Literature
1.
go back to reference Andreadou I, Iliodromitis EK, Rassaf T, Schulz R, Papapetropoulos A, Ferdinandy P (2015) The role of gasotransmitters NO, H2S and CO in myocardial ischaemia/reperfusion injury and cardioprotection by preconditioning, postconditioning and remote conditioning. Br J Pharmacol 172:1587–1606. doi:10.1111/bph.12811 CrossRefPubMed Andreadou I, Iliodromitis EK, Rassaf T, Schulz R, Papapetropoulos A, Ferdinandy P (2015) The role of gasotransmitters NO, H2S and CO in myocardial ischaemia/reperfusion injury and cardioprotection by preconditioning, postconditioning and remote conditioning. Br J Pharmacol 172:1587–1606. doi:10.​1111/​bph.​12811 CrossRefPubMed
3.
go back to reference Hausenloy D, Mwamure PK, Venugopal V, Harris J, Barnard M, Grundy E, Ashley E, Vichare S, Di Salvo C, Kolvekar S, Hayward M, Keogh B, MacAllister RJ, Yellon DM (2007) Effect of remote ischaemic preconditioning on myocardial injury in patients undergoing coronary artery bypass graft surgery: a randomised controlled trial. Lancet 370:575–579. doi:10.1016/S0140-6736(07)61296-3 CrossRefPubMed Hausenloy D, Mwamure PK, Venugopal V, Harris J, Barnard M, Grundy E, Ashley E, Vichare S, Di Salvo C, Kolvekar S, Hayward M, Keogh B, MacAllister RJ, Yellon DM (2007) Effect of remote ischaemic preconditioning on myocardial injury in patients undergoing coronary artery bypass graft surgery: a randomised controlled trial. Lancet 370:575–579. doi:10.​1016/​S0140-6736(07)61296-3 CrossRefPubMed
4.
go back to reference Hausenloy D, Candilio L, Evans R, Ariti C, Jenkins D, Kolvekar S, Knight R, Kunst G, Laing C, Nicholas J, Pepper J, Robertson S, Xenou M, Clayton T, Yellon D, The ERRICA Trial Investigators (2015) Effect of remote ischemic preconditioning on clinical outcomes in patients undergoing coronary artery bypass graft surgery. N Engl J Med 373:1408–1417. doi:10.1056/NEJMoa1413534 CrossRefPubMed Hausenloy D, Candilio L, Evans R, Ariti C, Jenkins D, Kolvekar S, Knight R, Kunst G, Laing C, Nicholas J, Pepper J, Robertson S, Xenou M, Clayton T, Yellon D, The ERRICA Trial Investigators (2015) Effect of remote ischemic preconditioning on clinical outcomes in patients undergoing coronary artery bypass graft surgery. N Engl J Med 373:1408–1417. doi:10.​1056/​NEJMoa1413534 CrossRefPubMed
5.
9.
go back to reference Janes RD, Johnstone DE, Brandys JC, Armour JA (1986) Functional and anatomical variability of canine cardiac sympathetic efferent pathways: implications for regional denervation of the left ventricle. Can J Physiol Pharmacol 64:958–969. doi:10.1139/y86-165 CrossRefPubMed Janes RD, Johnstone DE, Brandys JC, Armour JA (1986) Functional and anatomical variability of canine cardiac sympathetic efferent pathways: implications for regional denervation of the left ventricle. Can J Physiol Pharmacol 64:958–969. doi:10.​1139/​y86-165 CrossRefPubMed
10.
go back to reference Kleinbongard P, Neuhäuser M, Thielmann M, Kottenberg E, Peters J, Jakob H, Heusch G (2016) Confounders of cardioprotection by remote ischemic preconditioning in patients undergoing coronary artery bypass grafting. Cardiology 133:128–133. doi:10.1159/000441216 CrossRefPubMed Kleinbongard P, Neuhäuser M, Thielmann M, Kottenberg E, Peters J, Jakob H, Heusch G (2016) Confounders of cardioprotection by remote ischemic preconditioning in patients undergoing coronary artery bypass grafting. Cardiology 133:128–133. doi:10.​1159/​000441216 CrossRefPubMed
12.
go back to reference Kottenberg E, Musiolik J, Thielmann M, Jakob H, Peters J, Heusch G (2014) Interference of propofol with signal transducer and activator of transcription 5 activation and cardioprotection by remote ischemic preconditioning during coronary artery bypass grafting. J Thorac Cardiovasc Surg 147:376–382. doi:10.1016/j.jtcvs.2013.01.005 CrossRefPubMed Kottenberg E, Musiolik J, Thielmann M, Jakob H, Peters J, Heusch G (2014) Interference of propofol with signal transducer and activator of transcription 5 activation and cardioprotection by remote ischemic preconditioning during coronary artery bypass grafting. J Thorac Cardiovasc Surg 147:376–382. doi:10.​1016/​j.​jtcvs.​2013.​01.​005 CrossRefPubMed
13.
go back to reference Kottenberg E, Thielmann M, Kleinbongard P, Frey UH, Heine T, Jakob H, Heusch G, Peters J (2014) Myocardial protection by remote ischaemic pre-conditioning is abolished in sulphonylurea-treated diabetics undergoing coronary revascularisation. Acta Anaesthesiol Scand 58:453–462. doi:10.1111/aas.12278 CrossRefPubMed Kottenberg E, Thielmann M, Kleinbongard P, Frey UH, Heine T, Jakob H, Heusch G, Peters J (2014) Myocardial protection by remote ischaemic pre-conditioning is abolished in sulphonylurea-treated diabetics undergoing coronary revascularisation. Acta Anaesthesiol Scand 58:453–462. doi:10.​1111/​aas.​12278 CrossRefPubMed
14.
go back to reference Landoni G, Greco T, Biondi-Zoccai G, Neto CN, Febres D, Pintaudi M, Pasin L, Cabrini L, Finco G, Zangrillo A (2013) Anaesthetic drugs and survival: a Bayesian network meta-analysis of randomized trials in cardiac surgery. Br J Anaesth 111:886–896. doi:10.1093/bja/aet231 CrossRefPubMed Landoni G, Greco T, Biondi-Zoccai G, Neto CN, Febres D, Pintaudi M, Pasin L, Cabrini L, Finco G, Zangrillo A (2013) Anaesthetic drugs and survival: a Bayesian network meta-analysis of randomized trials in cardiac surgery. Br J Anaesth 111:886–896. doi:10.​1093/​bja/​aet231 CrossRefPubMed
15.
go back to reference Li J, Rohailla S, Gelber N, Rutka J, Sabah N, Gladstone RA, Wei C, Hu P, Kharbanda RK, Redington AN (2014) MicroRNA-144 is a circulating effector of remote ischemic preconditioning. Basic Res Cardiol 109:423–429. doi:10.1007/s00395-014-0423-z CrossRefPubMed Li J, Rohailla S, Gelber N, Rutka J, Sabah N, Gladstone RA, Wei C, Hu P, Kharbanda RK, Redington AN (2014) MicroRNA-144 is a circulating effector of remote ischemic preconditioning. Basic Res Cardiol 109:423–429. doi:10.​1007/​s00395-014-0423-z CrossRefPubMed
16.
go back to reference Meybohm P, Bein B, Brosteanu O, Cremer J, Gruenewald M, Stoppe C, Coburn M, Schaelte G, Böning A, Niemann B, Roesner J, Kletzin F, Strouhal U, Reyher C, Laufenberg-Feldmann R, Ferner M, Brandes IF, Bauer M, Stehr SN, Kortgen A, Wittmann M, Baumgarten G, Meyer-Treschan T, Kienbaum P, Heringlake M, Schön J, Sander M, Treskatsch Smul T, Wolwender E, Schilling T, Fuernau G, Hasenclever D, Zacharowski K, The RIPHeart Study Collaborators (2015) A multicenter trial of remote ischemic preconditioning for heart surgery. N Engl J Med 373:1397–1407. doi:10.1056/NEJMoa1413579 CrossRefPubMed Meybohm P, Bein B, Brosteanu O, Cremer J, Gruenewald M, Stoppe C, Coburn M, Schaelte G, Böning A, Niemann B, Roesner J, Kletzin F, Strouhal U, Reyher C, Laufenberg-Feldmann R, Ferner M, Brandes IF, Bauer M, Stehr SN, Kortgen A, Wittmann M, Baumgarten G, Meyer-Treschan T, Kienbaum P, Heringlake M, Schön J, Sander M, Treskatsch Smul T, Wolwender E, Schilling T, Fuernau G, Hasenclever D, Zacharowski K, The RIPHeart Study Collaborators (2015) A multicenter trial of remote ischemic preconditioning for heart surgery. N Engl J Med 373:1397–1407. doi:10.​1056/​NEJMoa1413579 CrossRefPubMed
17.
go back to reference Minisi AJ, Thames MD (1991) Activation of cardiac sympathetic afferents during coronary occlusion. Evidence for reflex activation of sympathetic nervous system during transmural myocardial ischemia in the dog. Circulation 84:357–367. doi:10.1161/01.CIR.84.1.357 CrossRefPubMed Minisi AJ, Thames MD (1991) Activation of cardiac sympathetic afferents during coronary occlusion. Evidence for reflex activation of sympathetic nervous system during transmural myocardial ischemia in the dog. Circulation 84:357–367. doi:10.​1161/​01.​CIR.​84.​1.​357 CrossRefPubMed
22.
23.
go back to reference Thielmann M, Kottenberg E, Kleinbongard P, Wendt D, Gedik N, Pasa S, Price V, Tsagakis K, Neuhäuser M, Peters J, Jakob H, Heusch G (2013) Cardioprotective and prognostic effects of remote ischaemic preconditioning in patients undergoing coronary artery bypass surgery: a single-centre randomised, double blind, controlled trial. Lancet 382:597–604. doi:10.1016/S0140-6736(13)61450-6 CrossRefPubMed Thielmann M, Kottenberg E, Kleinbongard P, Wendt D, Gedik N, Pasa S, Price V, Tsagakis K, Neuhäuser M, Peters J, Jakob H, Heusch G (2013) Cardioprotective and prognostic effects of remote ischaemic preconditioning in patients undergoing coronary artery bypass surgery: a single-centre randomised, double blind, controlled trial. Lancet 382:597–604. doi:10.​1016/​S0140-6736(13)61450-6 CrossRefPubMed
24.
go back to reference Zangrillo A, Musu M, Greco T, Di Prima AL, Matteazzi A, Testa V, Nardelli P, Febres D, Monaco F, Calabro MG, Ma J, Finco G, Landoni G (2015) Additive effect on survival of anaesthetic cardiac protection and remote ischemic preconditioning in cardiac surgery: a Bayesian network meta-analysis of randomized trials. PLoS One 10:e0134264. doi:10.1371/journal.pone.0134264 CrossRefPubMedPubMedCentral Zangrillo A, Musu M, Greco T, Di Prima AL, Matteazzi A, Testa V, Nardelli P, Febres D, Monaco F, Calabro MG, Ma J, Finco G, Landoni G (2015) Additive effect on survival of anaesthetic cardiac protection and remote ischemic preconditioning in cardiac surgery: a Bayesian network meta-analysis of randomized trials. PLoS One 10:e0134264. doi:10.​1371/​journal.​pone.​0134264 CrossRefPubMedPubMedCentral
25.
go back to reference Uhlig C, Bluth T, Schwarz K, Deckert S, Heinrich L, De Hert SD, Landoni G, Neto SN, Schultz MJ, Pelosi P, Schmitt J, de Abreu Gama (2016) Effects of volatile anesthetics on mortality and postoperative pulmonary and other complications in patients undergoing surgery: a systematic review and meta-analysis. Anesthesiology 124:1230–1245. doi:10.1097/ALN.0000000000001120 CrossRefPubMed Uhlig C, Bluth T, Schwarz K, Deckert S, Heinrich L, De Hert SD, Landoni G, Neto SN, Schultz MJ, Pelosi P, Schmitt J, de Abreu Gama (2016) Effects of volatile anesthetics on mortality and postoperative pulmonary and other complications in patients undergoing surgery: a systematic review and meta-analysis. Anesthesiology 124:1230–1245. doi:10.​1097/​ALN.​0000000000001120​ CrossRefPubMed
Metadata
Title
Anaesthetics and remote ischaemic preconditioning: do not stop the music, despite a (yet) unhappy marriage
Author
Jürgen Peters
Publication date
01-07-2016
Publisher
Springer Berlin Heidelberg
Published in
Basic Research in Cardiology / Issue 4/2016
Print ISSN: 0300-8428
Electronic ISSN: 1435-1803
DOI
https://doi.org/10.1007/s00395-016-0564-3

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