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Published in: Current Neurology and Neuroscience Reports 1/2015

01-01-2015 | Movement Disorders (M Okun, Section Editor)

An Update and Review of the Treatment of Myoclonus

Authors: Kelly Mills, Zoltan Mari

Published in: Current Neurology and Neuroscience Reports | Issue 1/2015

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Abstract

Recent advances in medications and surgical therapy for neurological disorders may offer new therapeutic options for the treatment of myoclonus. Appropriate therapy for myoclonus depends on the etiology, and in some cases, myoclonus can improve when the provoking cause is eliminated. When the underlying cause for the movements is not immediately reversible, localization, disease pathophysiology, and etiology may each play a role in determining the most appropriate symptomatic treatment of disabling myoclonic jerks. While the use of many agents is still based on small, open-label case series and anecdotes, there is a growing body of evidence from head-to-head comparative trials in several types of myoclonus that may help guide therapy. New therapies for refractory myoclonus, including sodium oxybate and even deep brain stimulation, are also being explored with increasing enthusiasm.
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Metadata
Title
An Update and Review of the Treatment of Myoclonus
Authors
Kelly Mills
Zoltan Mari
Publication date
01-01-2015
Publisher
Springer US
Published in
Current Neurology and Neuroscience Reports / Issue 1/2015
Print ISSN: 1528-4042
Electronic ISSN: 1534-6293
DOI
https://doi.org/10.1007/s11910-014-0512-2

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