Skip to main content
Top
Published in: Pediatric Cardiology 7/2009

01-10-2009 | Case Report

Amiodarone for Pediatric Resuscitation: A Word of Caution

Authors: Steven B. Fishberger, Robert L. Hannan, Elizabeth M. Welch, Anthony F. Rossi

Published in: Pediatric Cardiology | Issue 7/2009

Login to get access

Abstract

Intravenous administration of amiodarone has recently been recommended for use during pediatric resuscitation of pediatric patients with ventricular fibrillation or pulseless ventricular tachycardia. We present two pediatric patients who received amiodarone for polymorphic ventricular tachycardia, although they were ultimately determined to have congenital long QT syndrome. Amiodarone is contraindicated in this setting and may have exacerbated the ventricular arrhythmia.
Literature
1.
go back to reference American Heart Association (2005) American Heart Association 2005 guidelines for cardiopulmonary resuscitation and emergency cardiovascular care of pediatric and neonatal patients: Pediatric basic life support. Circulation 112:IV1–203 American Heart Association (2005) American Heart Association 2005 guidelines for cardiopulmonary resuscitation and emergency cardiovascular care of pediatric and neonatal patients: Pediatric basic life support. Circulation 112:IV1–203
2.
go back to reference Bar-Cohen Y, Silka MJ (2006) Congenital long QT syndrome: diagnosis and management in pediatric patients. Curr Treat Options Cardiovasc Med 8:387–395PubMedCrossRef Bar-Cohen Y, Silka MJ (2006) Congenital long QT syndrome: diagnosis and management in pediatric patients. Curr Treat Options Cardiovasc Med 8:387–395PubMedCrossRef
3.
go back to reference Figa FH, Gow RM, Hamilton RM, Freedom RM (1994) Clinical efficacy and safety of intravenous Amiodarone in infants and children. Am J Cardiol 74:573–577PubMedCrossRef Figa FH, Gow RM, Hamilton RM, Freedom RM (1994) Clinical efficacy and safety of intravenous Amiodarone in infants and children. Am J Cardiol 74:573–577PubMedCrossRef
4.
go back to reference Haas NA, Camphausen CK (2008) Impact of early and standardized treatment with amiodarone on therapeutic success and outcome in pediatric patients with postoperative tachyarrhythmia. J Thorac Cardiovasc Surg 136:1215–1222PubMedCrossRef Haas NA, Camphausen CK (2008) Impact of early and standardized treatment with amiodarone on therapeutic success and outcome in pediatric patients with postoperative tachyarrhythmia. J Thorac Cardiovasc Surg 136:1215–1222PubMedCrossRef
5.
go back to reference International Liaison Committee on Resuscitation (2005) International consensus on cardiopulmonary resuscitation and emergency cardiovascular care science with treatment recommendations. Part 6: Pediatric basic and advanced life support. Resuscitation 67:271–291CrossRef International Liaison Committee on Resuscitation (2005) International consensus on cardiopulmonary resuscitation and emergency cardiovascular care science with treatment recommendations. Part 6: Pediatric basic and advanced life support. Resuscitation 67:271–291CrossRef
6.
go back to reference Nkomo VT, Shen WK (2001) Amiodarone-induced long QT and polymorphic ventricular tachycardia. Am J Emerg Med 19:246–248PubMedCrossRef Nkomo VT, Shen WK (2001) Amiodarone-induced long QT and polymorphic ventricular tachycardia. Am J Emerg Med 19:246–248PubMedCrossRef
7.
go back to reference Perry JC, Fenrich AL, Hulse JE, Triedman JK, Friedman RA, Lamberti JJ (1996) Pediatric use of intravenous amiodarone: efficacy and safety in critically ill patients from a multicenter protocol. J Am Coll Cardiol 27:1246–1250PubMedCrossRef Perry JC, Fenrich AL, Hulse JE, Triedman JK, Friedman RA, Lamberti JJ (1996) Pediatric use of intravenous amiodarone: efficacy and safety in critically ill patients from a multicenter protocol. J Am Coll Cardiol 27:1246–1250PubMedCrossRef
8.
go back to reference Plumpton K, Justo R, Hass N (2005) Amiodarone for post-operative junctional ectopic tachycardia. Cardiol Young 15:13–18PubMedCrossRef Plumpton K, Justo R, Hass N (2005) Amiodarone for post-operative junctional ectopic tachycardia. Cardiol Young 15:13–18PubMedCrossRef
9.
go back to reference Saul JP, Scott WA, Brown S et al (2005) Intravenous amiodarone for incessant tachyarrhythmias in children: a randomized, double-blind, antiarrhythmic drug trial. Circulation 112:3470–3477PubMedCrossRef Saul JP, Scott WA, Brown S et al (2005) Intravenous amiodarone for incessant tachyarrhythmias in children: a randomized, double-blind, antiarrhythmic drug trial. Circulation 112:3470–3477PubMedCrossRef
Metadata
Title
Amiodarone for Pediatric Resuscitation: A Word of Caution
Authors
Steven B. Fishberger
Robert L. Hannan
Elizabeth M. Welch
Anthony F. Rossi
Publication date
01-10-2009
Publisher
Springer-Verlag
Published in
Pediatric Cardiology / Issue 7/2009
Print ISSN: 0172-0643
Electronic ISSN: 1432-1971
DOI
https://doi.org/10.1007/s00246-009-9470-x

Other articles of this Issue 7/2009

Pediatric Cardiology 7/2009 Go to the issue