Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.
ADVANCED SEARCH
Log in
Top
Pediatric Cardiology
Published in: Pediatric Cardiology 6/2009

01-08-2009 | Case Report

Amino-Terminal Pro-B-Type Natriuretic Peptide in Refractory Kawasaki Disease

Authors: Fernando Maria de Benedictis, Massimo Colaneri, Patrizia Osimani, Maria Grazia Bettuzzi

Published in: Pediatric Cardiology | Issue 6/2009

Login to get access

Abstract

Serum concentrations of brain natriuretic peptide and its amino-terminal cleavage pro-fragment, NT-proBNP, have never been reported in refractory Kawasaki disease. Changes in NT-proBNP levels after infliximab treatment in an infant with severe cardiovascular complications are reported here. The regular evaluation of this cardiac biomarker after infliximab treatment may have clinical relevance in patients with refractory Kawasaki disease and severe heart involvement.
Literature
1.
Burns JC, Mason WH, Haugher SB et al (2005) Infliximab treatment for refractory Kawasaki syndrome. J Pediatr 146:662–667PubMedCrossRef
2.
Burns JC, Best BM, Mejas A et al (2008) Infliximab treatment of immunoglobulin-resistant Kawasaki disease. J Pediatr 153:833–838PubMedCrossRef
3.
de Benedictis FM, Lattanzi B, Colaneri M (2008) Home monitoring anticoagulation therapy in infants. Arch Dis Child 93:714PubMed
4.
Johns MC, Stephenson C (2008) Amino-terminal pro-B-type natriuretic peptide testing in neonatal and pediatric patients. Am J Cardiol 10(Suppl):76A–81ACrossRef
5.
Kawamura T, Wago M, Kawaguchi H, Tahara M, Yuge M (2000) Plasma brain natriuretic peptide concentrations in patients with Kawasaki disease. Pediatr Int 42:241–248PubMedCrossRef
6.
Kurotobi S, Kawakami N, Shimizu K et al (2005) Brain natriuretic peptide as hormonal marker of ventricular diastolic dysfunction in children with Kawasaki disease. Pediatr Cardiol 26:425–430PubMedCrossRef
7.
Ma KK, Ogawa T, deBold AJ (2004) Selective upregulation of cardiac brain natriuretic peptide as the transcriptional and translational levels by proinflammatory cytokines and by conditioned medium derived from mixed lymphocyte reactions via p38 MAP kinase. J Mol Cell Cardiol 36:505–513PubMedCrossRef
8.
Matsubara T, Furukawa S, Yabuta K (1990) Serum levels of tumor necrosis factor, interleukin 2 receptor, and interferon-gamma in Kawasaki disease involved coronary-artery lesions. Clin Immunol Immunopathol 56:29–36PubMedCrossRef
9.
McCrindle BW, Li JS, Minich LL et al (2007) Coronary artery involvement in children with Kawasaki disease: risk factors from analysis of serial normalized measurements. Circulation 116:174–179PubMedCrossRef
10.
O’Connor MJ, Saulsbury FT (2007) Incomplete and atypical Kawasaki disease in a young infant: severe, recalcitrant disease responsive to infliximab. Clin Pediatr (Phila) 46:345–348CrossRef
11.
Oishi T, Fujieda M, Shiraishi T et al (2008) Infliximab treatment for refractory Kawasaki disease with coronary artery aneurysm. Circ J 72:850–852PubMedCrossRef
12.
Williams RV, Wilke VM, Tani LY, Minch LL (2002) Does abciximab enhance regression of coronary aneurysm resulting from Kawasaki disease? Pediatrics 109(1):E4PubMedCrossRef
Metadata
Title
Amino-Terminal Pro-B-Type Natriuretic Peptide in Refractory Kawasaki Disease
Authors
Fernando Maria de Benedictis
Massimo Colaneri
Patrizia Osimani
Maria Grazia Bettuzzi
Publication date
01-08-2009
Publisher
Springer-Verlag
Published in
Pediatric Cardiology / Issue 6/2009
Print ISSN: 0172-0643
Electronic ISSN: 1432-1971
DOI
https://doi.org/10.1007/s00246-009-9416-3

Other articles of this Issue 6/2009

Pediatric Cardiology 6/2009 Go to the issue

Original Article

Femoral Vein Access by Contrast-Guided Puncture in Cardiac Catheterization in Patients Under One Year of Age

Original Article

Hypocalcemic Rickets and Dilated Cardiomyopathy: Case Reports and Review of Literature

Case Report

Acute Myocardial Infarction as the Presenting Symptom of Systemic Lupus Erythematosus

Original Article

Left Ventricular Systolic Function of Newborns with Asphyxia Evaluated by Tissue Doppler Imaging

Case Report

Right-Sided Pulmonary Venous Obstruction Between a Right Aortic Arch and an Amplatzer Septal Occlusion Device Following Closure of a Secundum Atrial Septal Defect

Original Article

Arterial Stiffness is Increased in American Adolescents Compared to Japanese Counterparts

ACC 2024 Congress Coverage

Year in Review: Heart failure and cardiomyopathies

Heart Failure Video

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.

Watch now

Semaglutide benefits people with type 2 diabetes and obesity-related heart failure

16-04-2024 Type 2 Diabetes News

Incentivised to exercise

11-04-2024 Lifestyle Modifications News

New intervention for STEMI-related cardiogenic shock

10-04-2024 Myocardial Infarction News

» View more highlights on the ACC 2024 congress hub page

Image Credits